Skip to main content
SpringerLink
Log in

Endoskopische Detektion von frühen Läsionen im Gastrointestinaltrakt in der Allgemeinbevölkerung und in Risikokollektiven

  • Chapter
  • First Online:
Prävention gastroenterologischer Tumorerkrankungen

  • 751 Accesses

Zusammenfassung

Das Erkennen von Frühkarzinomen oder prämalignen Konditionen im Gastrointestinaltrakt ist eine diagnostische Herausforderung. Diese Veränderungen verursachen in der Regel keine Symptome. In einigen Fällen kann es zu okkulten Blutabgängen kommen. Frühkarzinome sind häufig klein und unscheinbar und können bei einer Routineendoskopie übersehen werden. Ziel jeder Endoskopie (Gastroskopie und Koloskopie) ist es daher mit voller Aufmerksamkeit zu untersuchen und alle Auffälligkeiten zu erkennen, zu charakterisieren und ggfs. endoskopisch zu entfernen. Deutsche und europäische Leitlinien geben klare Handlungsempfehlungen, die eine qualitativ hochwertige Endoskopie charakterisieren.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Banks M, Graham D, Jansen M et al (2019) British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut. https://doi.org/10.1136/gutjnl-2018-318126 pii: gutjnl-2018-318126. [Epub ahead of print]

    Article  PubMed  Google Scholar 

  • Barclay RL, Vicari JJ, Doughty AS et al (2006) Colonoscopic withdrawal times and adenoma detection during screening colonoscopy. N Engl J Med 355(24):2533–2541

    Article  CAS  PubMed  Google Scholar 

  • Brenner H, Altenhofen L, Kretschmann J et al (2015) Trends in adenoma detection rates during the first 10 years of the german screening colonoscopy program. Gastroenterology 149(2):356–366

    Article  PubMed  Google Scholar 

  • Brenner H, Chen C (2018) The colorectal cancer epidemic: challenges and opportunities for primary, secondary and tertiary prevention. Br J Cancer 119(7):785–792

    Article  PubMed  PubMed Central  Google Scholar 

  • Corley DA, Levin TR, Doubeni CA (2014) Adenoma detection rate and risk of colorectal cancer and death. N Engl J Med 370(26):2541

    CAS  PubMed  Google Scholar 

  • Dekker E, Kiesslich R (2019) Advanced imaging: the impressive success story of gastrointestinal endoscopy. Endoscopy 51(3):209–211

    Article  PubMed  Google Scholar 

  • di Pietro M, Canto MI, Fitzgerald RC (2018) Endoscopic management of early adenocarcinoma and squamous cell carcinoma of the esophagus: screening, diagnosis, and therapy. Gastroenterology 154(2):421–436

    Article  PubMed  Google Scholar 

  • Domper Arnal MJ, Ferrández Arenas Á, Lanas Arbeloa Á (2015) Esophageal cancer: risk factors, screening and endoscopic treatment in Western and Eastern countries. World J Gastroenterol 21(26):7933–7943

    Article  PubMed  PubMed Central  Google Scholar 

  • East JE, Atkin WS, Bateman AC et al (2017) British Society of Gastroenterology position statement on serrated polyps in the colon and rectum. Gut 66(7):1181–1196

    Article  CAS  PubMed  Google Scholar 

  • Facciorusso A, Del Prete V, Buccino V et al (2018a) Full-spectrum versus standard colonoscopy for improving polyp detection rate: A systematic review and meta-analysis. J Gastroenterol Hepatol 33(2):340–346. https://doi.org/10.1111/jgh.13859

    Article  PubMed  Google Scholar 

  • Facciorusso A, Triantafyllou K, Murad MH et al (2018b) Compared abilities of endoscopic techniques to increase colon adenoma detection rates: a network meta-analysis. Clin Gastroenterol Hepatol 17(12):2439–2454.e25 pii: S1542-3565(18)31335-1

    Article  PubMed  Google Scholar 

  • Gandhi J, Davidson C, Hall C et al (2017) Population-based study demonstrating an increase in colorectal cancer in young patients. Br J Surg 104(8):1063–1068

    Article  CAS  PubMed  Google Scholar 

  • Gralnek IM, Segol O, Suissa A et al (2013) A prospective cohort study evaluating a novel colonoscopy platform featuring full-spectrum endoscopy. Endoscopy 45(9):697–702

    Article  PubMed  Google Scholar 

  • Gupta N, Gaddam S, Wani SB et al (2012) Longer inspection time is associated with increased detection of high-grade dysplasia and esophageal adenocarcinoma in Barrett’s esophagus. Gastrointest Endosc 76(3):531–538

    Article  PubMed  Google Scholar 

  • Hoffman A, Manner H, Rey JW, Kiesslich R (2017) A guide to multimodal endoscopy imaging for gastrointestinal malignancy – an early indicator. Nat Rev Gastroenterol Hepatol 14(7):421–434

    Article  PubMed  Google Scholar 

  • Hooi JK, Lai WY, Ng WK et al (2017) Global prevalence of helicobacter pylori infection: systematic review and meta-analysis. Gastroenterology 153(2):420–429

    Article  PubMed  Google Scholar 

  • http://www.lebensblicke.de/darmkrebs/

  • IJspeert JE, Bastiaansen BA, van Leerdam ME et al (2016) Development and validation of the WASP classification system for optical diagnosis of adenomas, hyperplastic polyps and sessile serrated adenomas/polyps. Gut 65(6):963–970

    Article  PubMed  Google Scholar 

  • Kandiah K, Chedgy FJQ, Subramaniam S et al (2018) International development and validation of a classification system for the identification of Barrett’s neoplasia using acetic acid chromoendoscopy: the Portsmouth acetic acid classification (PREDICT). Gut 12:2085–2091

    Article  Google Scholar 

  • Kaminski MF, Regula J, Kraszewska E et al (2010) Quality indicators for colonoscopy and the risk of interval cancer. N Engl J Med 362(19):1795–1803

    Article  CAS  PubMed  Google Scholar 

  • Kiesslich R, Neurath MF (2005) Endoscopic detection of early lower gastrointestinal cancer. Best Pract Res Clin Gastroenterol 19(6):941–961

    Article  CAS  PubMed  Google Scholar 

  • Kudo S, Tamura S, Nakajima T et al (1996) Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 44(1):8–14

    Article  CAS  PubMed  Google Scholar 

  • Labenz J, Koop H, Tannapfel A, Kiesslich R, Hölscher AH (2015) The epidemiology, diagnosis, and treatment of Barrett’s carcinoma. Dtsch Arztebl Int 112(13):224–233

    PubMed  PubMed Central  Google Scholar 

  • Laine L, Kaltenbach T, Barkun A et al (2015) SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastroenterology 148(3):639–651.e28

    Article  PubMed  Google Scholar 

  • Leitlinienprogramm Onkologie (2019) S3-Leitlinie, Kolorektales Karzinom, Langversion 2.1. – Januar 2019, AWMF-Registernummer: 021/007OL, https://www.dgvs.de/wp-content/uploads/2019/01/LL_KRK_Langversion_2.1.pdf

  • Leong RW, Ooi M, Corte C et al (2017) Full-spectrum endoscopy improves surveillance for dysplasia in patients with inflammatory bowel diseases. Gastroenterology 152(6):1337–1344

    Article  PubMed  Google Scholar 

  • Li M, Ali SM, Umm-a-Omarah Gilani S et al (2014) Kudo’s pit pattern classification for colorectal neoplasms: a meta-analysis. World J Gastroenterol 20(35):12649–12656

    Article  PubMed  PubMed Central  Google Scholar 

  • Misawa M, Kudo SE, Mori Y et al (2018) Artificial intelligence-assisted polyp detection for colonoscopy: initial experience. Gastroenterology 154(8):2027–2029

    Article  PubMed  Google Scholar 

  • Moehler M et al (2011) Magenkarzinom „Diagnostik und Therapie der Adenokarzinome des Magens und ösophagogastralen Übergangs“ AWMF-Register-Nummer (032-009OL) Langversion 02.2012. Zeitschrift fur Gastroenterologie 49(4):461–531. https://www.dgvs.de/wp-content/uploads/2016/10/LL_Magenkarzinom_Langversion.pdf

  • Mori Y, Berzin TM, Kudo SE (2019) Artificial intelligence for early gastric cancer: early promise and the path ahead. Gastrointest Endosc 89(4):816–817

    Article  PubMed  Google Scholar 

  • Neumann H, Kiesslich R, Wallace MB, Neurath MF (2010) Confocal laser endomicroscopy: technical advances and clinical applications. Gastroenterology 139(2):388–392, 392.e1–2

    Article  PubMed  Google Scholar 

  • Peters Y, Al-Kaabi A, Shaheen NJ et al (2019) Barrett oesophagus. Nat Rev Dis Primers 5(1):35

    Article  PubMed  Google Scholar 

  • Porschen R et al (2018) S3-Leitlinie – Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus Langversion 2.0 – Dezember 2018 AWMF-Registernummer: 021/023OL. Zeitschrift für Gastroenterologie 57(03):e120–e120. https://www.dgvs.de/wp-content/uploads/2019/04/0708_zgastro-8335712-Leitlinie_Online-PDF.pdf

  • Rees CJ, Rajasekhar PT, Wilson A et al (2017) Narrow band imaging optical diagnosis of small colorectal polyps in routine clinical practice: the Detect Inspect Characterise Resect and Discard 2 (DISCARD 2) study. Gut 66(5):887–895

    Article  PubMed  Google Scholar 

  • Rembacken BJ, Fujii T, Cairns A, Dixon MF, Yoshida S, Chalmers DM, Axon AT (2000) Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK. Lancet 355(9211):1211–1214

    Article  CAS  PubMed  Google Scholar 

  • Repici A, Wallace MB, East JE et al (2019) Efficacy of per-oral methylene blue formulation for screening colonoscopy. Gastroenterology 156(8):2198–2207

    Article  CAS  PubMed  Google Scholar 

  • Sharma P, Dent J, Armstrong D et al (2006) The development and validation of an endoscopic grading system for Barrett’s esophagus: the Prague C & M criteria. Gastroenterology 131(5):1392–1399

    Article  PubMed  Google Scholar 

  • Shirin H, Shpak B, Epshtein J et al (2019) G-EYE colonoscopy is superior to standard colonoscopy for increasing adenoma detection rate: an international randomized controlled trial (with videos). Gastrointest Endosc 89(3):545–553

    Article  PubMed  Google Scholar 

  • Smith RA, Andrews KS, Brooks D et al (2017) Cancer screening in the United States, 2017: a review of current American Cancer Society guidelines and current issues in cancer screening. CA Cancer J Clin 67(2):100–121

    Article  PubMed  Google Scholar 

  • Song J, Zhang J, Wang J et al (2015) Meta-analysis of the effects of endoscopy with narrow band imaging in detecting dysplasia in Barrett’s esophagus. Dis Esophagus 28(6):560–566

    Article  CAS  PubMed  Google Scholar 

  • Teh JL, Tan JR, Lau L et al (2015) Longer examination time improves detection of gastric cancer during diagnostic upper gastrointestinal endoscopy. Clin Gastroenterol Hepatol 13(3):480–487.e2

    Article  PubMed  Google Scholar 

  • Triantafyllou K, Gkolfakis P, Tziatzios G et al (2019) Effect of Endocuff use on colonoscopy outcomes: a systematic review and meta-analysis. World J Gastroenterol 25(9):1158–1170

    Article  PubMed  PubMed Central  Google Scholar 

  • van de Wetering AJP, Bogie RMM, Cabbolet ACOG et al (2018) Update on the role of chromoendoscopy in colonoscopic surveillance of patients with Lynch syndrome. Eur J Gastroenterol Hepatol 30(10):1116–1124

    Article  PubMed  Google Scholar 

  • von Rahden BH, Stein HJ, Weber A et al (2008) Critical reappraisal of current surveillance strategies for Barrett’s esophagus: analysis of a large German Barrett’s database. Dis Esophagus 21(8):685–689

    Article  Google Scholar 

  • Xiong YQ, Ma SJ, Hu HY et al (2018) Comparison of narrow-band imaging and confocal laser endomicroscopy for the detection of neoplasia in Barrett’s esophagus: a meta-analysis. Clin Res Hepatol Gastroenterol 42(1):31–39

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. HELIOS Dr. Horst Schmidt Kliniken Wiesbaden, Wiesbaden, Deutschland

    Ralf Kiesslich

Authors
  1. Ralf Kiesslich
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ralf Kiesslich .

Editor information

Editors and Affiliations

  1. Chefarzt der Med. Klinik II und Ärztlicher Direktor Medizinische Klinik, Diakonissenkrankenhaus Mannheim, Mannheim, Germany

    Dieter Schilling

  2. ehem. Direktor Medizinische Klinik C am Klinikum Ludwigshafen am Rhein, Vorstandsvorsitzender der Stiftung LebensBlicke, Ludwigshafen, Germany

    Jürgen F. Riemann

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Kiesslich, R. (2020). Endoskopische Detektion von frühen Läsionen im Gastrointestinaltrakt in der Allgemeinbevölkerung und in Risikokollektiven. In: Schilling, D., F. Riemann, J. (eds) Prävention gastroenterologischer Tumorerkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58879-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-58879-6_6

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-58878-9

  • Online ISBN: 978-3-662-58879-6

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation