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The Role of Platelet-Rich Plasma and Growth Factors in Rotator Cuff Repair

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Rotator Cuff Across the Life Span

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Abstract

The role of biologic therapy in augmentation of tendon to bone healing has gained significant interest in orthopedic surgery, including in rotator cuff repair. Augmentation is of particular interest in challenging revision cases after failed rotator cuff repair, chronic retracted rotator cuff tears with poor tissue quality, and rotator cuff tears in patients with compromised healing potential such as smokers, diabetics, and those with other chronic medical comorbidities. This chapter briefly reviews the available literature on different biologic therapies, including growth factors, platelet-rich plasma, bone marrow aspirate, and stem cells. The senior author’s current indications and technique of utilizing biologic augmentation in arthroscopic rotator cuff repair will also be detailed.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, UCONN Musculoskeletal Institute, University of Connecticut, Farmington, CT, USA

    Laura A. Vogel, Santiago Rodriguez, Mary Beth R. McCarthy & Augustus D. Mazzocca

  2. Department of Orthopaedic Sports Medicine, Technical University of Munich, Munich, Germany

    Andreas Voss

Authors
  1. Laura A. Vogel
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  2. Santiago Rodriguez
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  3. Mary Beth R. McCarthy
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  4. Andreas Voss
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  5. Augustus D. Mazzocca
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Correspondence to Augustus D. Mazzocca .

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Editors and Affiliations

  1. Orthopaedic Sportsmedicine, University of Munich (TUM), Orthopaedic Sportsmedicine, Munich, Bayern, Germany

    Andreas B. Imhoff

  2. Department of Orthopaedics, Tulane University School of Medicine, Department of Orthopaedics, New Orleans, LA, USA

    Felix H. Savoie III

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Vogel, L.A., Rodriguez, S., McCarthy, M.B.R., Voss, A., Mazzocca, A.D. (2019). The Role of Platelet-Rich Plasma and Growth Factors in Rotator Cuff Repair. In: Imhoff, A.B., Savoie, F.H. (eds) Rotator Cuff Across the Life Span. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58729-4_4

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  • DOI: https://doi.org/10.1007/978-3-662-58729-4_4

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