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Erkrankungen peripherer Nerven

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Neurologische Pathophysiologie

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Zusammenfassung

Es werden die unterschiedlichen Pathomechanismen ausgewählter peripherer Nervenerkrankungen diskutiert und die vielfältigen Ursachen dargestellt. Neben der häufig auftretenden, diabetischen Polyneuropathie werden die akut und chronisch inflammatorischen Neuropathien besprochen. Es werden die verschiedenen Schädigungsmuster auf makroskopischer als auch histologischer Ebene dargestellt und beteiligte Stoffwechselwege, zelluläre Schädigungsmechanismen und immunologische Hintergründe beleuchtet. Insbesondere die ursächlichen Auslöser sowie die Autoimmunmechanismen des Guillain-Barré-Syndroms (GBS) als auch der chronischen inflammatorisch-demyelinisierenden Polyneuropathie werden betrachtet und Therapiemöglichkeiten kritisch diskutiert. Das Prinzip des molekularen Mimikry wird vermittelt.

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Author information

Authors and Affiliations

  1. Klinik für Neurologie, Agaplesion Bethesda Krankenhaus Wuppertal, Wuppertal, Deutschland

    Dr. med. D. Sturm

  2. St.-Josef-Hospital, Klinik für Neurologie, Ruhr-Universität Bochum, Bochum, Deutschland

    Dr. med. K. Pitarokoili

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  1. Dr. med. D. Sturm
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  2. Dr. med. K. Pitarokoili
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Corresponding authors

Correspondence to D. Sturm , K. Pitarokoili , D. Sturm or K. Pitarokoili .

Editor information

Editors and Affiliations

  1. Agaplesion Bethesda KH Wuppertal, Wuppertal, Deutschland

    Dietrich Sturm

  2. Ruhr-Universität Bochum, Bochum, Deutschland

    Anne-Sophie Biesalski  & Oliver Höffken  & 

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Sturm, D., Pitarokoili, K. (2019). Erkrankungen peripherer Nerven. In: Sturm, D., Biesalski, AS., Höffken, O. (eds) Neurologische Pathophysiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-56784-5_6

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  • DOI: https://doi.org/10.1007/978-3-662-56784-5_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-56783-8

  • Online ISBN: 978-3-662-56784-5

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