Abstract
Although primary liver tumours comprise only 5% of pediatric extracranial solid tumours, more than two-thirds are malignant. In Europe and North America, primary malignant liver tumours are the tenth most common pediatric cancer. Malignant tumours can arise from primary hepatocytes, such as in hepatoblastoma and hepatocellular carcinoma, or from the biliary tract (rhabdomyosarcoma). Leiomyosarcoma (arising from hepatic smooth muscle tissue) and angiosarcoma (arising from blood vessels) are rare primary hepatic tumours. Malignant liver tumours require complete resection for cure. Benign hepatic tumours, which account for about one third of all liver tumours in children, also occasionally will require liver resection. Hemangiomas are the most common benign liver tumour, followed by focal nodular hyperplasia. Less common benign tumours include hepatic adenoma and mesenchymal hamartoma.
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Lim, I.I.P., La Quaglia, M.P. (2019). Liver Tumours. In: Puri, P., Höllwarth, M. (eds) Pediatric Surgery. Springer Surgery Atlas Series. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-56282-6_54
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DOI: https://doi.org/10.1007/978-3-662-56282-6_54
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