Abstract
Renal neoplasms in childhood are usually malignant, the most common being nephroblastoma Wilms tumour (WT). The incidence varies from 10.9 per million in the United States to 2.5 per million in China. A genetic predisposition exists, and nephrogenic cell clusters, (which are premalignant lesions), are found in one third of patients with WT. Some syndromes are associated with WT:
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WAGR (WT, Aniridia, Genitourinary anomalies, mental Retardation)
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Denys-Drash (WT, disorders of sexual development, nephropathy)
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Beckwith-Wiedemann (exomphalos, macroglossia, visceromegaly)
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Hemihypertrophy is associated with an increased incidence of WT
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Suggested Reading
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Hammond, P., Carachi, R. (2019). Wilms Tumour. In: Puri, P., Höllwarth, M. (eds) Pediatric Surgery. Springer Surgery Atlas Series. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-56282-6_53
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DOI: https://doi.org/10.1007/978-3-662-56282-6_53
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