Skip to main content

Concepts in Allergy to Pectus Metal Implants

  • Chapter
  • First Online:
Chest Wall Deformities

Abstract

Allergy to pectus implants is infrequent. Cutaneous allergic reactions to stainless steel Nuss bars may take the form of skin erosions, granulomas, erythema or seromas; keloids have also been reported, posssibly as an end result of an erosion in a predisposed patient. Pleural effusions and pericarditis have also been implicated as systemic reactions to metals. Epicutaneous patch testing is a tool that can be used to identify allergy to metal implants. Although routine pre-operative patch testing is not recommended for most implants and prostheses unless the patient has a significant history of metal sensitivity or previous cutaneous or systemic reaction to an implant or device, Nuss’s group now performs metal patch testing on all patients priot to the Nuss procedure. Patients in whom a diagnosis of allergy to an implant is made have been treated with corticosteroids and antihistamines, removal of the implant, or replacement of the implant. Titanium implants are generally well tolerated in patients with nickel metal allergy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Saxena A, Willital GH. Surgical correction of funnel chest using titanium struts. Surg Childh Intern VI. 1998;4:230–2.

    Google Scholar 

  2. Kelly RE, Goretsky MJ, Obermeyer R, Kuhn MA, Redlinger R, Haney TS, Moskowitz A, Nuss D. Twenty-One years of experience with minimally invasive repair of pectus excavatum by the Nuss procedure in 1215 patients. Ann Surg. 2010;252(6):1072–81.

    Article  PubMed  Google Scholar 

  3. Vegunta RK, Pacheco PE, Wallace LJ, Pearl RH. Complications associated with the Nuss procedure: continued evolution of the learning curve. Am J Surg. 2008;195(3):313–6.

    Article  PubMed  Google Scholar 

  4. Morchuis WJ, Folgering HT, Barentsz JO, Cox AL, van Lier HJ, Lacquet LK. Exercise cardiorespiratory function before and one year after operation for pectus excavatum. J Thorac Cardiovasc Surg. 1994;107:1403–9.

    Google Scholar 

  5. Nuss D. Minimally invasive surgical repair of pectus excavatum. Semin Pediatr Surg. 2008;17(3):209–17.

    Article  PubMed  Google Scholar 

  6. Rushing GD, Goretsky MJ, Gustin T, et al. When it is not an infection: metal allergy after the Nuss procedure for repair of pectus excavatum. J Pediatr Surg. 2007;42(1):93–7.

    Article  PubMed  Google Scholar 

  7. Watanabe A, Watanabe T, Obama T, Ohsawa H, Mawatari T, Ichimiya Y, Abe T. The use of a lateral stabilizer increases the incidence of wound trouble following the Nuss procedure. Ann Thorac Surg. 2004;77:296–300.

    Article  PubMed  Google Scholar 

  8. Raff GW, Wong MS. Sternal plating to correct an unusual complication of the Nuss procedure: erosion of a pectus bar through the sternum. Ann Thorac Surg. 2008;85:1100–1.

    Article  PubMed  Google Scholar 

  9. Pilegaard HK, Licht PB. Early results following Nuss operation for pectus excavatum-a single institution experience of 383 patients. Interact Cardiovasc Thorac Surg. 2007;7:54–7.

    Article  PubMed  Google Scholar 

  10. Al-Assiri A, Kravarusic D, Wong V, Dicken B, Millbrandt K, Sigalet DL. Operative innovation to the “Nuss” procedure for pectus excavatum: operative and function effects. J Pediatr Surg. 2009;44:888–92.

    Article  PubMed  Google Scholar 

  11. Aneja S, Taylor JS, Soldes O, DiFiore J. Dermatitis in patients undergoing the Nuss procedure for correction of pectus excavatum. Contact Dermatitis. 2011;65(6):317–21.

    Article  PubMed  Google Scholar 

  12. Castellani C, Saxena AK, Zebedin D, Hoellwarth ME. Pleural and pericardial morbidity after minimal access repair of pectus excavatum. Langenbecks Arch Surg. 2009;394:717–21.

    Article  CAS  PubMed  Google Scholar 

  13. Haecker FM, Sesia SB. Intraoperative use of the vacuum bell for elevating the sternum during the Nuss procedure. J Laparoendosc Adv Surg Tech A. 2012;22(9):934–6.

    Article  PubMed  Google Scholar 

  14. Kezic S. Genetic susceptibility to occupational contact dermatitis. Int J Immunopathol Pharmacol. 2011;24(1 Suppl):73S–8.

    CAS  PubMed  Google Scholar 

  15. Schnuch A, Westphal G, Mössner R, Uter W, Reich K. Genetic factors in contact allergy – review and future goals. Contact Dermatitis. 2011;64(1):2–23.

    Article  CAS  PubMed  Google Scholar 

  16. Biomet Microfixation. Pectus Bar, Pectus Excavatum Correction. http://www.biometmicrofixation.com/downloads/PE-r45k1003.pdf.

  17. Zug KA, Warshaw EM, Fowler Jr JF, Maibach HI, Belsito DL, Pratt MD, Sasseville D, Storrs FJ, Taylor JS, Mathias CG, Deleo VA, Rietschel RL, Marks J. Patch-test results of the North American contact dermatitis group 2005–2006. Dermatitis. 2009;20(3):149–60.

    CAS  PubMed  Google Scholar 

  18. Josefson A, Farm G, Meding B. Validity of self-reported nickel allergy. Contact Dermatitis. 2010;62(5):289–93.

    Article  PubMed  Google Scholar 

  19. Thyssen JP, Menné T. Metal allergy – a review on exposures, penetration, genetics, prevalence, and clinical implications. Chem Res Toxicol. 2010;23(2):309–18.

    Article  CAS  PubMed  Google Scholar 

  20. Thyssen JP, Menne T, Schalock PC, Taylor JS, Maibach HI. Pragmatic approach to the clinical work-up of patients with putative allergic disease to metallic orthopaedic implants before and after surgery. Br J Dermatol. 2011;164(3):473–8.

    CAS  PubMed  Google Scholar 

  21. Kubba R, Taylor JS, Marks KE. Cutaneous complications of orthopedic implants. A two-year prospective study. Arch Dermatol. 1981;117:554–60.

    Article  CAS  PubMed  Google Scholar 

  22. Aneja S, Taylor JS, Billings SD, Honari G, Sood A. Post-implantation erythema in 3 patients and a review of reticular telangiectatic erythema. Contact Dermatitis. 2011;64(5):280–8.

    Article  PubMed  Google Scholar 

  23. Basko-Plluska JL, Thyssen JP, Schalock PC. Cutaneous and systemic hypersensitivity reactions to metallic implants. Dermatitis. 2011;22(2):65–79.

    PubMed  Google Scholar 

  24. Rietschel RL, Fowler JF. Fisher’s contact dermatitis. 5th ed. Baltimore: Williams & Wilkins; 2000.

    Google Scholar 

  25. Gaspari AA. The role of keratinocytes in the pathophysiology of contact dermatitis. Immunol Allergy Clin North Am. 1997;17:377.

    Article  Google Scholar 

  26. Stab Jensen C, Lisby S, Baadsgaard O, Byrialsen K, Menne T. Release of nickel ions fom stainless steel alloys used in dental braces and their patch test reactivity in nickel-sensitive individuals. Contact Dermatitis. 2003;48:300–4.

    Article  Google Scholar 

  27. Schalock PC, Menné T, Johansen JD, Taylor JS, Maibach HI, Lidén C, Bruze M, Thyssen JP. Hypersensitivity reactions to metallic implants – diagnostic algorithm and suggested patch test series for clinical use. Contact Dermatitis. 2012;66(1):4–19.

    Article  CAS  PubMed  Google Scholar 

  28. Warshaw EM, Nelsen DD, Sasseville D, et al. Positivity ratio and reaction index: patch-test quality-control metrics applied to the North American contact dermatitis group database. Dermatitis. 2010;21(2):91–7.

    CAS  PubMed  Google Scholar 

  29. Honari G, Ellis SG, Wilkoff BL, Aronica MA, Svenson LG, Taylor JS. Hypersensitivity reactions associated with endovascular devices. Contact Dermatitis. 2008;59:7–22.

    Article  PubMed  Google Scholar 

  30. Krob HA, Fleischer Jr AB, D’Agostino Jr R, et al. Prevalence and relevance of contact dermatitis allergens: a meta-analysis of 15 years of published T.R.U.E. test data. J Am Acad Dermatol. 2004;51:349.

    Article  PubMed  Google Scholar 

  31. Anon: Pectus surgery metal Pach testing guidelines. Children’s Hospital of the King’s Daughters, Revised 25 Apr 2012.

    Google Scholar 

  32. Osawa H, Mawatari T, Watannage A, Abe T. New material for Nuss procedure. Ann Thorac Cardiovasc Surg. 2004;10(5):301–3.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to James S. Taylor MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Aneja, S., Taylor, J.S., Sood, A., Honari, G., DiFiore, J.D. (2017). Concepts in Allergy to Pectus Metal Implants. In: Saxena, A. (eds) Chest Wall Deformities. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53088-7_25

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-53088-7_25

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-53086-3

  • Online ISBN: 978-3-662-53088-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics