Zusammenfassung
Plazenta-induzierter Schwangerschaftserkrankungen (z.B. intrauterine Wachstumsretardierung, Präeklampsie und vorzeitige Plazentalösung) werden durch eine fehlerhafte Plazentation ausgelöst. Eine biochemische Möglichkeit zur Differentialdiagnose kann die Bestimmung des sFlt-1/PlGF-Quotienten darstellen. Durch eine fetale Wachstumsretardierung kann es zu Hypoxämie und intrauterinem Fruchttod kommen. Zur Diagnosestellung wird u.a. die Dopplersonografie verwendet.
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Literatur
Andraweera PH, Dekker GA, Roberts CT (2012) The vascular endothelial growth factor family in adverse pregnancy outcomes. Hum Reprod Update 18(4): 436–457
Baschat AA (2011) Neurodevelopment following fetal growth restriction and its relationship with antepartum parameters of placental dysfunction. Ultrasound Obstet Gynecol 37(5): 501–514
Baschat AA, Gembruch U (2003) The cerebroplacental Doppler ratio revisited. Ultrasound Obstet Gynecol 21(2): 124–127
Burton GJ, Woods AW, Jauniaux E, Kingdom JCP (2009) Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy. Placenta 30(6): 473–482
Flenady V, Frøen JF, Pinar H, Torabi R, Saastad E, Guyon G et al. (2009) An evaluation of classification systems for stillbirth. BMC Pregnancy Childbirth 9: 24
Hanna J, Goldman-Wohl D, Hamani Y, Avraham I, Greenfield C, Natanson-Yaron S et al. (2006) Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med 12(9): 1065–1074
Herraiz I, Dröge LA, Gómez-Montes E, Henrich W, Galindo A, Verlohren S (2014) Characterization of the soluble fms-like tyrosine kinase-1 to placental growth factor ratio in pregnancies complicated by fetal growth restriction. Obstet Gynecol 124(2): 265–273
Levine RJ, Maynard SE, Qian C, Lim K-H, England LJ, Yu KF et al. (2004) Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350(7): 672–683
Maynard SE, Venkatesha S, Thadhani R, Karumanchi SA (2005) Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia. Pediatr Res 57(5 Pt 2): 1R–7R
Meekins JW, Pijnenborg R, Hanssens M, McFadyen IR (1994) A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies. Br J Obs Gynaecol 101(8): 669–674
Odibo AO, Riddick C, Pare E, Stamilio DM, Macones GA (2005) Cerebroplacental Doppler ratio and adverse perinatal outcomes in intrauterine growth restriction. J Ultrasound Med 24(9): 1223–1228
Ott W (1988) The diagnosis of altered fetal growth. Obstet Gynecol Clin North Am 15(2): 237–263
Ptacek I, Sebire NJ, Man JA, Brownbill P, Heazell AEP (2014) Systematic review of placental pathology reported in association with stillbirth. Placenta 35(8): 552–562
Verlohren S, Herraiz I, Lapaire O, Schlembach D, Moertl M, Zeisler Het al. (2012) The sFlt-1/PlGF ratio in different types of hypertensive pregnancy disorders and its prognostic potential in preeclamptic patients. Am J Obstet Gynecol 206(1): 58.e1–8
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Spratte, J., Fluhr, H. (2017). Plazentationsstörungen und fetale Wachstumsretardierung. In: Toth, B. (eds) Fehlgeburten Totgeburten Frühgeburten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-50424-6_40
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DOI: https://doi.org/10.1007/978-3-662-50424-6_40
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