Zusammenfassung
Organische psychische Störungen zeichnen sich durch ein heterogenes psychopathologisches Bild mit einer gleichermaßen heterogenen Ätiologie aus. In Abhängigkeit von der Ätiopathogenese werden organische psychische Störungen im engeren Sinne (d. h. solche Störungen, deren organisches Korrelat zerebral lokalisierbar ist) von symptomatischen psychischen Störungen (d. h. solchen Störungen, denen eine allgemeine medizinische Erkrankung zugrunde liegt) unterschieden. In diesem Beitrag werden die einzelnen Störungsbilder aus dem Bereich der organischen/symptomatischen Psychosyndrome anhand ihrer Symptompräsentation vorgestellt.
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Literatur
Abbate C, Trimarchi PD, Inglese S et al (2014) Preclinical polymodal hallucinations for 13 years before dementia with Lewy bodies. Behav Neurol 27, 694296. Epub 27 Apr 2014
Ahuja N (2000) Organic catatonia: a review. Indian J Psychiatry 42:327–346
Aichner F (1984) Phänomenologie des Klüver-Bucy Syndroms beim Menschen. Fortschr Neurol Psychiatr 52:375–397
Albert MS, DeKosky ST, Dickson D et al (2011) The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement 7:270–279
American Psychiatric Association (2013) DSM-5. Philadelphia
Arciniegas DB, Silver JM (2006) Pharmacotherapy of posttraumatic cognitive impairments. Behav Neurol 17:25–42
Arendt T, Bigl V, Arendt A, Tennstedt A (1983) Loss of neurons in the nucleus basalis of Meynert in Alzheimer’s disease, paralysis agitans and Korsakoff’s disease. Acta Neuropathol 61:101–108
Arenz D (2000) Psychiatrische Doppelgängerphänomene unter besonderer Berücksichtigung des Capgras-Syndroms. Fortschr Neurol Psychiatr 68:516–522
Assal F, Mendez MF (2003) Intermetamorphosis in a patient with Alzheimer’s disease. J Neuropsychiatry Clin Neurosci 15:246–247
Baldwin R, Jeffries S, Jackson A et al (2005) Neurological findings in late-onset depressive disorder: comparison of individuals with and without depression. Br J Psychiatry 186:308–313
Bauer J, Stadtmüller G, Qualmann J, Bauer H (1995) Prämorbide psychologische Prozesse bei Patienten mit Alzheimerkrankheit und Patienten mit vaskulärer Demenz. Z Gerontol Geriatr 28:179–189
Bender M (1956) Syndrome of isolated episode of confusion with amnesia. J Hillside Hosp 5:212–215
Berli R, Hutter A, Waespe W, Bachli EB (2009) Transient global amnesia – not so rare after all. Swiss Med Wkly 16:288–292
Bhandary SK, Peter R, Bhat S (2008) Delusional parasitosis in ENT. Indian J Otolaryngol Head Neck Surg 60:387–389
Bickel H, Mosch E, Seigerschmidt E et al (2006) Prevalence and persistence of mild cognitive impairment among elderly patients in general hospitals. Dement Geriatr Cogn Disord 21:242–250
Brooks JO 3rd, Hoblyn JC (2005) Secondary mania in older adults. Am J Psychiatry 162:2033–2038
Brüning R, Schmidtke K, Strupp M, Reinhardt M (1999) Transiente globale Amnesie: Klinik und Pathophysiologie. Dtsch Ärztebl 96:A-2602–A-2606
Caplan L (1990) Transient global amnesia: characteristic features and overview. In: Markowitsch HJ (Hrsg) Transient global amnesia and related disorders. Hogrefe & Huber, Toronto, S 15–27
Carlino AR, Stinnett JL, Kim DR (2013) New onset of bipolar disorder in late life. Psychosomatics 54:94–97
Christodoulou GN, Margariti M, Kontaxakis VP, Christodoulou NG (2009) The delusional misidentification syndromes: strange, fascinating, and instructive. Curr Psychiatry Rep 11:185–189
Cicerone KD, Azulay J, Trott C (2009) Methodological quality of research on cognitive rehabilitation after traumatic brain injury. Arch Phys Med Rehabil 90(Suppl 11):52–59
Coebergh JA, Lauw RF, Bots R et al (2015) Musical hallucinations: review of treatment effects. Front Psychol 6:814–825
Cooper C, Li R, Lyketsos C, Livingston G (2013) Treatment for mild cognitive impairment: systematic review. Br J Psychiatry 203:255–264
Cornelius JR, Day NL, Fabrega H Jr et al (1991) Characterizing organic delusional syndrome. Arch Gen Psychiatry 48:749–753
Cornelius JR, Fabrega H Jr, Mezzich J et al (1993) Characterizing organic mood syndrome, depressed type. Compr Psychiatry 34:432–440
Crook T, Bartus RT, Ferris SH et al (1986) Age-associated memory impairment: proposed diagnostic criteria and measures of clinical change (NIMH-Workgroup). Dev Neuropsychol 2:261–276
Cummings JL (1997) The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology 48(Suppl 6): 10–16
Damasio H, Grabowski T, Frank R et al (1994) The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science 264(5162):1102–1105
Davison K (1983) Schizophrenia-like psychoses associated with organic cerebral disorders: a review. Psychiatr Dev 1:1–34
Day E, Bentham P, Callaghan R et al (2004) Thiamine for Wernicke-Korsakoff syndrome in people at risk from alcohol abuse. Cochrane Database Syst Rev CD004033
DeKosky ST, Williamson JD, Fitzpatrick AL et al (2008) Ginkgo biloba for prevention of dementia: a randomized controlled trial. JAMA 300:2253–2262
Devanand DP, Pradhaban G, Liu X et al (2007) Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology 68:828–836
Devanand DP, Liu X, Tabert MH et al (2008) Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer’s disease. Biol Psychiatry 15:871–879
Direkze M, Bayliss SG, Cuttings SJ (1971) Primary tumors of the frontal lobe. Br J Clin Pract 25:207–213
Drach LM, Adler L (2010) Medikamentöse Alternativen zu Antipsychotika bei Demenzkranken mit Verhaltensstörungen. Psychopharmakotherap 17:264–273
Drachman DA, Arbit J (1966) Memory and the hippocampal complex. II. Is memory a multiple process? Arch Neurol 15(1):52–61
Eisenberg DP, Aniskin DB, White L et al (2009) Structural differences within negative and depressive syndrome dimensions in schizophrenia, organic brain disease, and major depression: a confirmatory factor analysis of the positive and negative syndrome scale. Psychopathology 42:242–248
Ellison JM, Harper DG, Berlow Y, Zeranski L (2008) Beyond the „C“ in MCI: noncognitive symptoms in amnestic and non-amnestic mild cognitive impairment. CNS Spectr 13:66–72
Evers S (2006) Musical hallucinations. Curr Psychiatry Rep 8:205–210
Farlow MR (2009) Treatment of mild cognitive impairment (MCI). Curr Alzheimer Res 6:362–367
Feinstein A, Hershkop S, Ouchterlony D et al (2002) Posttraumatic amnesia and recall of a traumatic event following traumatic brain injury. J Neuropsychiatry Clin Neurosci 14:25–30
Felix MM, Castro LH, Maia AC Jr, da Rocha AJ (2005) Evidence of acute ischemic tissue change in transient global amnesia in magnetic resonance imaging: case report and literature review. J Neuroimaging 15:203–205
Fleminger S (1994) Delusional misidentification: an exemplary symptom illustrating an interaction between organic brain disease and psychological processes. Psychopathology 27:161–167
Förstl H, Besthorn C, Burns A et al (1994) Delusional misidentification in Alzheimer’s disease: a summary of clinical and biological aspects. Psychopathology 27:194–199
Förstl H, Bickel H, Frölich L et al (2008) Leichte kognitive Beeinträchtigungen mit Vorzeichen rascher Verschlechterung. Dtsch Med Wochenschr 133:431–436
Förstl H, Perneczky R, Karenberg A et al (2009) Persönlichkeit im höheren Lebensalter. Nervenarzt 80:1275–1282
Fraser LM, O’Carroll RE, Ebmeier KP (2008) The effect of electroconvulsive therapy on autobiographical memory: a systematic review. J ECT 24:10–17
Gardner BK, O’Connor DW (2008) A review of the cognitive effects of electroconvulsive therapy in older adults. J ECT 24:68–80
Geda YE, Roberts RO, Knopman DS et al (2010) Physical exercise, aging, and mild cognitive impairment: a population-based study. Arch Neurol 67:80–86
Glowinski R, Payman V, Frencham K (2008) Confabulation: a spontaneous and fantastic review. Aust N Z J Psychiatry 42:932–940
Good MI (1993) The concept of an organic dissociative syndrome: what is the evidence? Harv Rev Psychiatry 1(3):145–157
Graham JE, Rockwood K, Beattie BL et al (1997) Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet 349:1793–1796
Greenop KR, Almeida OP, Hankey GJ (2009) Premorbid personality traits are associated with post-stroke behavioral and psychological symptoms: a three-month follow-up study in Perth, Western Australia. Int Psychogeriatr 21:1063–1071
Hampel H, Mitchell A, Blennow K et al (2004) Core biological marker candidates of Alzheimer’s disease – perspectives for diagnosis, prediction of outcome and reflection of biological activity. J Neural Transm 111:247–272
Hanninen T, Hallikainen M, Koivisto K et al (1995) A follow-up study of age-associated memory impairment: neuropsychological predictors of dementia. J Am Geriatr Soc 43:1007–1015
Helmstaedter C, Witt JA (2012) Multifactorial etiology of interictal behavior in frontal and temporal lobe epilepsy. Epilepsia 53:1765–1773
Hodges JR, Warlow CP (1990) Syndromes of transient amnesia: towards a classification. A study of 153 cases. J Neurol Neurosurg Psychiatry 53:834–843
House A, Dennis M, Molyneux A et al (1989) Emotionalism after stroke. Br Med J 298:991–994
Ingenhoven T, Lafay P, Rinne T et al (2010) Effectiveness of pharmacotherapy for severe personality disorders: meta-analyses of randomized controlled trials. J Clin Psychiatry 71:14–25
Inzitari D, Pantoni L, Lamassa M et al (1997) Emotional arousal and phobia in transient global amnesia. Arch Neurol 54:866–873
Jekel K, Damian M, Wattmo C et al (2015) Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review. Alzheimers Res Ther 7:17–37
Jicha GA, Parisi JE, Dickson DW et al (2006) Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia. Arch Neurol 63:674–681
Jørgensen A, Jørgensen MB (2009) Organic catatonia after apoplexy. Ugeskr Laeger 171:2572–2573
Kapur N (1990) Transient epileptic amnesia: a clinically distinct form of neurological memory disorder. In: Markowitsch HJ (Hrsg) Transient global amnesia and related disorders. Hogrefe & Huber, Toronto, S 140–151
Kessler RC, Keller MB, Wittchen HU (2001) The epidemiology of generalized anxiety disorder. Psychiatr Clin North Am 24:19–39
Kim E, Ku J, Namkoong K et al (2009) Mammillothalamic functional connectivity and memory function in Wernicke’s encephalopathy. Brain 132:369–376
Kirchhoff BA, Lugar HM, Smith SE (2013) Hypoglycaemia-induced changes in regional brain volume and memory function. Diabet Med 30:e151–e156
Kondo K, Niino M, Shido K (1994) A case–control study of Alzheimer’s disease in Japan – significance of life-styles. Dementia 5:314–326
Kopelman MD (1995) The Korsakoff syndrome. Br J Psychiatry 166:154–173
Kopelman MD (2002) Disorders of memory. Brain 125:2152–2190
Kopelman MD, Thomson AD, Guerrini I, Marshall EJ (2009) The Korsakoff syndrome: clinical aspects, psychology and treatment. Alcohol Alcohol 44:148–154
Krauthammer C, Klerman GL (1978) Secondary mania: manic syndromes associated with antecedent physical illness or drugs. Arch Gen Psychiatry 35:1333–1339
Kühl K-P (2008) Mild cognitive impairment (MCI). In: Mahlberg R, Gutzmann H (Hrsg) Demenzerkrankungen. Deutscher Ärzte-Verlag, Köln, S 75–81
Kumral E, Deveci EE, Erdoğan C, Enüstün C (2015) Isolated hippocampal infarcts: vascular and neuropsychological findings. J Neurol Sci 356:83–89
Lang FU, Dudeck M, Becker T, Jäger M (2015) Die organische Persönlichkeitsstörung: Konzeptuelle Grundlagen, Klinik und Therapie. Nervenarzt 86:332–4, 336–9
Larrieu S, Letenneur L, Orgogozo JM et al (2002) Incidence and outcome of mild cognitive impairment in a population-based prospective cohort. Neurology 59:1594–1599
Lauter H (1988) Die Organischen Psychosyndrome. In: Kisker KP, Lauter H, Meyer J-E et al (Hrsg) Organische Psychosen. Psychiatrie der Gegenwart, Bd 6. Springer, Berlin/Heidelberg/New York, S 3–56
Leentjes AF, Diefenbacher A (2006) A survey of delirium guidelines in Europe. J Psychosom Res 61(1):123–128
Levin HS, High WM, Eisenberg HM (1988) Learning and forgetting during posttraumatic amnesia in head injured patients. J Neurol Neurosurg Psychiatry 51:14–20
Levy R (1994) Aging-associated cognitive decline. Int Psychogeriatr 6:63–68
Lishman WA (1998) Organic psychiatry, 3. Aufl. Blackwell Science, Oxford
Mackenzie TB, Popkin MK (1983) Organic anxiety syndrome. Am J Psychiatry 140:342–344
Markowitsch HJ, Calabrese P, Neufeld H et al (1999) Retrograde amnesia for world knowledge and preserved memory for autobiographic events. A case report. Cortex 35:243–252
Mikkelsen RL, Middelboe T, Pisinger C, Stage KB (2004) Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD). A review. Nord J Psychiatry 58:65–70
Mitchell AJ (2008) The clinical significance of subjective memory complaints in the diagnosis of mild cognitive impairment and dementia: a meta-analysis. Int J Geriatr Psychiatry 23:1191–1202
Morris JC, Storandt M, Miller JP et al (2001) Mild cognitive impairment represents early-stage Alzheimer disease. Arch Neurol 58:397–405
Mufson EJ, Binder L, Counts SE et al (2012) Mild cognitive impairment: pathology and mechanisms. Acta Neuropathol 123:13–30
Nordberg A, Carter SF, Rinne J et al (2013) A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease. Eur J Nucl Med Mol Imaging 40:104–114
O’Connor M, Vefaillie M (2002) The amnesic syndrome: overview and subtypes. In: Baddeley AD, Kopelman MD, Wilson BA (Hrsg) Handbook of memory borders, 2. Aufl. Wiley, Chichester, S 145–166
Olesen J, Jørgensen MB (1986) Leao’s spreading depression in the hippocampus explains transient global amnesia. A hypothesis. Acta Neurol Scand 73:219–220
Petersen RC, Smith GE, Waring SC et al (1999) Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 56:303–308
Petry S, Cummings JL, Hill MA, Shapira J (1989) Personality alterations in dementia of the Alzheimer type: a three-year follow-up study. J Geriatr Psychiatry Neurol 2:203–207
Podoll K, Osterheider M, Noth J (1989) Das Charles Bonnet Syndrom. Fortschr Neurol Psychiatr 57:43–60
Porter RJ, Douglas K, Knight RG (2008) Monitoring of cognitive effects during a course of electroconvulsive therapy: recommendations for clinical practice. J ECT 24:25–34
Quinette P, Guillery-Girard B, Dayan J et al (2006) What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases. Brain 129:1640–1658
Rasquin SM, Lodder J, Visser PJ et al (2005) Predictive accuracy of MCI subtypes for Alzheimer’s disease and vascular dementia in subjects with mild cognitive impairment: a 2-year follow-up study. Dement Geriatr Cogn Disord 19:113–119
Rentrop M, Theml T, Förstl H (2002) Wahnhafte Missidentifikationen. Fortschr Neurol Psychiatr 70:313–320
Ridley NJ, Draper B, Withall A (2013) Alcohol-related dementia: an update of the evidence. Alzheimers Res Ther 5:3
Roberts AH (1979) Severe accidental head injury: an assessment of long-term prognosis. Macmillan, London
Robinson RG, Kubos KL, Starr LB et al (1984) Mood disorders in stroke patients. Importance of location of lesion. Brain 107:81–93
Rose D, Fleischmann P, Wykes T et al (2003) Patients’ perspectives on electroconvulsive therapy: systematic review. BMJ 326:1363–1365
Rozzini L, Costardi D, Chilovi BV et al (2007) Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors. Int J Geriatr Psychiatry 22:356–360
Sanjuan J, Gonzalez JC, Aguilar EJ et al (2004) Pleasurable auditory hallucinations. Acta Psychiatr Scand 110:273–278
Schönknecht P, Pantel J, Kruse A, Schröder J (2005) Prevalence and natural course of aging-associated cognitive decline in a population-based sample of young-old subjects. Am J Psychiatry 162(11):2071–2077
Schreiber SJ, Doepp F, Klingebiel R, Valdueza JM (2005) Internal jugular vein valve incompetence and intracranial venous anatomy in transient global amnesia. J Neurol Neurosurg Psychiatry 76:509–513
Shah NJ, Marshall JC, Zafiris O et al (2001) The neural correlates of person familiarity. A functional magnetic resonance imaging study with clinical implications. Brain 124(4):804–815
Silver JM, Koumaras B, Meng X et al (2009) Long-term effects of rivastigmine capsules in patients with traumatic brain injury. Brain Inj 23:123–132
Slater E, Beard AW, Glithero E (1963) The schizophrenia-like psychoses of epilepsy. Br J Psychiatry 109:95–150
Snowdon J (1991) A retrospective case-note study of bipolar disorder in old age. Br J Psychiatry 158:485–490
Sollberger M, Stanley CM, Wilson SM et al (2009) Neural basis of interpersonal traits in neurodegenerative diseases. Neuropsychologia 47:2812–2827
Stasiek C, Zetin M (1985) Organic manic disorders. Psychosomatics 26:394–396, 399, 402
Stevens JR, Hermann BP (1981) Temporal lobe epilepsy, psychopathology, and violence: the state of the evidence. Neurology 31:1127–1132
Storandt M, Grant EA, Miller JP, Morris JC (2006) Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI. Neurology 67:467–473
Strang J, Edwards G (1993) Cocaine and crack. Br Med J 229:337–338
Subramaniam H, Dennis MS, Byrne EJ (2007) The role of vascular risk factors in late onset bipolar disorder. Int J Geriatr Psychiatry 22:733–737
Takeda M, Tanino S, Nishinuma K et al (1985) A case of hypophyseal prolactinoma with treatable delusions of dermatozoiasis. Acta Psychiatr Scand 72:470–475
Tohen M, Shulman KI, Satlin A (1994) First-episode mania in late life. Am J Psychiatry 151:130–132
UK ECT Review Group (2003) Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis. Lancet 361:799–808
Unverzagt FW, Smith DM, Rebok GW et al (2009) The Indiana Alzheimer Disease Center’s Symposium on mild cognitive impairment. Cognitive training in older adults: lessons from the ACTIVE Study. Curr Alzheimer Res 6:375–383
Van der Werf YD, Witter MP, Uylings HB, Jolles J (2000) Neuropsychology of infarctions in the thalamus: a review. Neuropsychologia 38:613–627
Victor M, Adams RD, Collins GH (1971) The Wernicke-Korsakoff syndrome. A clinical and pathological study of 245 patients, 82 with post-mortem examinations. Contemp Neurol Ser 7:1–206
Visser PJ, Verhey FR, Hofman PA et al (2002) Medial temporal lobe atrophy predicts Alzheimer’s disease in patients with minor cognitive impairment. J Neurol Neurosurg Psychiatry 72:491–497
Vos SJ, van Rossum IA, Verhey F et al (2013) Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI. Neurology 80(12):1124–1132
Wang C, Yu JT, Wang HF et al (2014) Non-pharmacological interventions for patients with mild cognitive impairment: a meta-analysis of randomized controlled trials of cognition-based and exercise interventions. J Alzheimers Dis 42(2):663–678
Warren DE, Duff MC, Magnotta V et al (2012) Long-term neuropsychological, neuroanatomical, and life outcome in hippocampal amnesia. Clin Neuropsychol 26:335–369
Wetterling T, Lanfermann H (2002) Organische Psychische Störungen. Steinkopff, Darmstadt
Weyerer S, Bickel H (2006) Grundriss Gerontologie: Epidemiologie psychischer Erkrankungen im höheren Lebensalter. Kohlhammer, Stuttgart
Winblad B, Palmer K, Kivipelto M et al (2004) Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Intern Med 256:240–246
Wise MG, Rundell JR (1999) Anxiety and neurological disorders. Semin Clin Neuropsychiatry 4:98–102
Wolter DK (2008) Alkohol, Wernicke-Korsakow-Syndrom und alkoholassoziierte Demenzen. In: Mahlberg R, Gutzmann H (Hrsg) Demenzerkrankungen. Deutscher Ärzte-Verlag, Köln, S 49–55
Zeman AZ, Boniface SJ, Hodges JR (1998) Transient epileptic amnesia: a description of the clinical and neuropsychological features in 10 cases and a review of the literature. J Neurol Neurosurg Psychiatry 64:435–443
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Gutzmann, H., Rapp, M. (2017). Organische Psychosyndrome. In: Möller, HJ., Laux, G., Kapfhammer, HP. (eds) Psychiatrie, Psychosomatik, Psychotherapie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49295-6_60
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