Skip to main content
SpringerLink
Log in

Lichttherapie

  • Chapter
  • First Online:
Psychiatrie, Psychosomatik, Psychotherapie

Part of the book series: Springer Reference Medizin ((SRM))

  • 35k Accesses

Zusammenfassung

Der therapeutische Effekt der Lichtherapie wurde erstmals in den 1980er-Jahren des vergangenen Jahrhunderts systematisch untersucht und es zeigte sich, dass Patienten mit einer Herbst-/Winter- bzw. einer Lichtmangeldepression günstig auf Lichttherapie ansprechen. Die Lichtintensität sollte zwischen 2500 und 10.000 Lux (gemessen an den Augen) liegen und entsprechend der Lichtintensität sollte die Dauer der Lichttherapie zwischen einer 1/2–4 h pro Tag betragen. Im Vergleich zur Psychopharmakotherapie tritt der antidepressive Effekt bereits ab dem 3. Tag ein. Eine verordnete antidepressive Medikation kann gleichzeitig weiter verabreicht werden. Die wenigen bis jetzt zur Verfügung stehenden psychophysiologischen Untersuchungen lassen erkennen, dass dem serotonergen System eine besondere Bedeutung zukommt. Interessanterweise haben jedoch auch Medikamente, die primär die noradrenergen bzw. dopaminergen Stoffwechelwege aktivieren, einen günstigen Erfolg gezeigt. Die Lichttherapie bei den nicht saisonal abhängigen Depressionen weist keine so deutlichen Effekte auf und kann als Zusatztherapie zur Psychopharmkotherapie gegebenenfalls angewandt werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Similar content being viewed by others

Literatur

  • Carlsson A, Svennerholm L, Winblad B (1980) Seasonal and ciradian monoamine variations in human brains examined post mortem. Acta Psychiatr Scand Suppl 280:75–85

    Article  CAS  PubMed  Google Scholar 

  • Dilsaver SC, Jaeckle RS (1990) Winter depression responds to an open trial of tranylcypromine. J Clin Psychiatry 51:326–329

    CAS  PubMed  Google Scholar 

  • Dilsaver SC, Del Medico VJ, Quadri A, Jaeckle RS (1990) Pharmacological responsiveness of winter depression. Psychopharmacol Bull 26:303–309

    CAS  PubMed  Google Scholar 

  • Fleischhacker WW, Kasper S (1991) Timing of phototherapy and occurance of mania. Biol Psychiatry 29:1156–1160

    Article  Google Scholar 

  • Golden RN, Gaynes BN, Ekstrom RD et al (2005) The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. Am J Psychiatry 162:656–662

    Article  PubMed  Google Scholar 

  • Heßelman B, Habeler A, Praschak-Rieder N et al (1999) Mirtazapine in seasonal affective disorder (SAD) – a preliminary report. Hum Psychopharmacol 14:59–62

    Article  Google Scholar 

  • Hilger E, Willeit M, Praschak-Rieder N et al (2001) Reboxetine in seasonal affective disorder: an open trial. Eur Neuropsychopharmacol 11:1–5

    Article  CAS  PubMed  Google Scholar 

  • Hollwich F (1955) Der Einfluß des Augenlichtes auf die Regulation des Stoffwechsels. Klin Monatsbl Augenheilkd 23:95–136

    Google Scholar 

  • Jacobsen FM, Murphy DL, Rosenthal NE (1989) The role of serotonin in seasonal affective disorder and the antidepressant response to phototherapy. In: Rosenthal NE, Blehar MC (Hrsg) Seasonal affective disorders and phototherapy. Guilford, New York, S 333–341

    Google Scholar 

  • Kasper S (1994) Diagnostik, Epidemiologie und Therapie der saisonal abhängigen Depression (SAD). Nervenarzt 65:69–72

    CAS  PubMed  Google Scholar 

  • Kasper S, Möller HJ (Hrsg) (2004) Herbst/-Winterdepression und Lichttherapie. Springer, Wien/New York

    Google Scholar 

  • Kasper S, Neumeister A (1998) Non-pharmacological treatments for depression – focus on sleep deprivation and light therapy. In: Briley M, Montgomery S (Hrsg) Antidepressant therapy at the dawn of the third millennium. Dunitz, London, S 255–278

    Google Scholar 

  • Kasper S, Praschak-Rieder N (1997) Diagnosis and treatment of subsyndromal seasonal affective disorder (S-SAD). In: Judd L, Saletu B, Filip V (Hrsg) Basic and clinical science of mental and addictive disorders (Bibl Psychiatr. No. 167). Karger, Basel, S 11–20

    Google Scholar 

  • Kasper S, Wehr TA, Rosenthal NE (1988a) Saisonal abhängige Depressionsformen (SAD). I. Grundlagen und klinische Beschreibung des Syndroms. Nervenarzt 59:191–199

    CAS  PubMed  Google Scholar 

  • Kasper S, Wehr TA, Rosenthal NE (1988b) Saisonal abhängige Depressionsformen (SAD). II. Beeinflussung durch Fototherapie und biologische Ergebnisse. Nervenarzt 59:200–214

    CAS  PubMed  Google Scholar 

  • Kasper S, Rogers LBS, Yancey A et al (1989a) Phototherapy in individuals with and without subsyndromal seasonal affective disorder. Arch Gen Psychiatry 46:837–844

    Article  CAS  PubMed  Google Scholar 

  • Kasper S, Wehr TA, Bartko JJ et al (1989b) Epidemiological findings of seasonal changes in mood and behavior. A telephon survey of Montgomery County, Maryland, USA. Arch Gen Psychiatry 46:823–833

    Article  CAS  PubMed  Google Scholar 

  • Kasper S, Ruhrmann HT, Möller HJ (1992) Recurrent brief depression and its relationship to seasonal affective disorders. Eur Arch Psychiatry Clin Neurosci 242:20–26

    Article  CAS  PubMed  Google Scholar 

  • Kasper S, Ruhrmann S, Neumann S, Möller HJ (1994a) Use of light therapy in German psychiatric hospitals. Europ Psychiatry 9:288–292

    Google Scholar 

  • Kasper S, Ruhrmann S, Schuchardt HM (1994b) The effects of light therapy in treatment indications other than seasonal affective disorder (SAD). In: Holick MF, Jung EG (Hrsg) Biologic effects of light therapy. De Gruyter, Berlin/New York, S 206–218

    Google Scholar 

  • Kasper S, Neumeister A, Rieder-Praschak N et al (1996) Serotonergic mechanisms in the pathophysiology and treatment of seasonal affective disorder. In: Holick MF, Jung EG (Hrsg) Biological effects of light 1995. De Gruyter, Berlin/New York, S 325–331

    Google Scholar 

  • Konstantinidis A, Praschak-Rieder N, Winkler D et al (2010) Milnacipran in seasonal affective disorder. Int J Psychiat Clin (Im Druck)

    Google Scholar 

  • Lam RW, Gorman CP, Michalon M et al (1995) Multi-centre, placebo-controlled study of fluoxetine in seasonal affective disorder. Am J Psychiatry 152:1765–1770

    Article  CAS  PubMed  Google Scholar 

  • Leppamaki S, Partonen T, Vakkuri O et al (2003) Effect of controlled-release melatonin on sleep quality, mood and quality of life in subjects with seasonal or weather-associated changes in mood and behaviour. Eur Neuropsychopharmacol 13:137–145

    Article  CAS  PubMed  Google Scholar 

  • Lewy AJ, Kern HA, Rosenthal NE, Wehr TA (1982) Bright artificial light treatment of a manic-depressive patient with a seasonal mood cycle. Am J Psychiatry 139:1496–1498

    Article  CAS  PubMed  Google Scholar 

  • Lewy AL, Sack RL, Miller S, Hoban TM (1987) Antidepressant and circadian phase-shifting effects of light. Science 235:352–354

    Article  CAS  PubMed  Google Scholar 

  • Lingjaerde O, Haggag A (1992) Moclobemide in winter depression: some preliminary results form an open trial. Nord J Psychiatry 46:201–203

    Article  Google Scholar 

  • Martinez B, Kasper S, Ruhrmann S, Möller HJ (1994) Hypericum in the treatment of seasonal affective disorders. J Geriatr Psychiatry Neurol 7:29–33

    Article  Google Scholar 

  • Martiny K, Lunde M, Simonsen C et al (2004) Relapse prevention by citalopram in SAD patients responding to 1 week of light therapy. A placebo-controlled study. Acta Psychiatr Scand 109:230–234

    Article  CAS  PubMed  Google Scholar 

  • McGrath RE, Buckwald B, Resnick EV (1990) The effect of L-tryptophan on seasonal affective disorder. J Clin Psychiatry 51:162–163

    CAS  PubMed  Google Scholar 

  • Modell JG, Rosenthal NE (2004) Once-daily bupropion XL for the prevention of seasonal major depressive episodes. Neuropsychopharmacology 29(Suppl 1):157

    Google Scholar 

  • Moscovitch A, Blashko CA, Eagles JM, the International Collaborative Group on Sertraline in the Treatment of Outpatients with Seasonal Affective Disorder et al (2004) A placebo-controlled study of sertraline in the treatment of outpatients with seasonal affective disorder. Psychopharmacology (Berl) 171:390–397

    Article  CAS  Google Scholar 

  • Neumeister A, Praschak-Rieder N, Heßelmann B et al (1997) Rapid tryptophan depletion in drug-free depressed patients with seasonal affective disorder. Am J Psychiatry 154:1153–1155

    Article  CAS  PubMed  Google Scholar 

  • Neumeister A, Turner E, Matthews J et al (1998) Effects of tryptophan depletion versus catecholamine depletion in patients with seasonal affective disorder in remission with light therapy. Arch Gen Psychiatry 55:524–530

    Article  CAS  PubMed  Google Scholar 

  • O’Rourke D, Wurtman JJ, Wurtman RJ et al (1989) Treatment of seasonal affective disorder with d-fenfluramine. J Clin Psychiatry 50:343–347

    PubMed  Google Scholar 

  • Oren DA, Mould DE, Schwartz PJ et al (1994) A controlled trial of levodopa plus carbidopa in the treatment of winter seasonal affective disorder: a test of the dopamine hypothesis. J Clin Psychopharmacol 14:196–200

    Article  CAS  PubMed  Google Scholar 

  • Pail G, Huf W, Pjrek E et al (2010) Bright light therapy in the treatment of mood disorders. Neuropsychobiology (im Druck)

    Google Scholar 

  • Partonen T, Lönnqvist J (1996) Moclobemide and fluoxetine in treatment of seasonal affective disorder. J Affect Disord 41:93–99

    Article  CAS  PubMed  Google Scholar 

  • Pjrek E, Winkler D, Stastny J et al (2004) Bright light therapy in seasonal affective disorder – does it suffice? Eur Neuropsychopharmacol 14:347–351

    Article  CAS  PubMed  Google Scholar 

  • Pjrek E, Winkler D, Kasper S (2005) Pharmacotherapy of seasonal affective disorder. CNS Spectr 10:664–669

    Article  PubMed  Google Scholar 

  • Pjrek E, Winkler D, Konstantinidis A, Willeit M et al (2007a) Agomelatine in the treatment of seasonal affective disorder. Psychopharmacology (Berl) 190:575–579

    Article  CAS  Google Scholar 

  • Pjrek E, Winkler D, Stastny J et al (2007b) Escitalopram in seasonal affective disorder: results of an open trial. Pharmacopsychiatry 40:20–24

    Article  CAS  PubMed  Google Scholar 

  • Pjrek E, Willeit M, Praschak-Rieder N et al (2008) Treatment of seasonal affective disorder with duloxetine: an open-label study. Pharmacopsychiatry 41:100–105

    Article  CAS  PubMed  Google Scholar 

  • Pjrek E, Konstantinidis A, Hilger E et al (2009) Therapeutic effects of escitalopram and reboxetine in seasonal affective disorder: a pooled analysis. J Psychiatr Res 43:792–797

    Article  PubMed  Google Scholar 

  • Praschak-Rieder N, Willeit M, Wilson AA et al (2008) Seasonal variation in human brain serotonin transporter binding. Arch Gen Psychiatry 65:1072–1078

    Article  PubMed  Google Scholar 

  • Rosen LN, Targum SD, Terman M et al (1990) Prevalence of seasonal affective disorder at four latitudes. Psychiatry Res 31:131–144

    Article  CAS  PubMed  Google Scholar 

  • Rosenthal NE, Sack DA, Gillin JC et al (1984) Seasonal affective disorder: a description of the syndrome and preliminary findings with light therapy. Arch Gen Psychiatry 41:72–80

    Article  CAS  PubMed  Google Scholar 

  • Rosenthal NE, Sack DA, Jacobsen FM et al (1986) Melatonin in seasonal affective disorder. J Neural Transm 21(Suppl 2):257–267

    CAS  Google Scholar 

  • Ruhrmann S, Kasper S, Hawellek B et al (1993) Fluoxetine as a treatment alternative to light therapy in seasonal affective disorder (SAD). Pharmacopsychiatry 26:193

    Google Scholar 

  • Schlager DS (1994) Early-morning administration of short-acting β-blockers for treatment of winter depression. Am J Psychiatry 151:1383–1385

    Article  CAS  PubMed  Google Scholar 

  • Skwerer RG, Jacobsen FM, Duncan CC et al (1988) Neurobiology of seasonal affective disorder and phototherapy. J Biol Rhythms 3:135–154

    Article  CAS  PubMed  Google Scholar 

  • Teicher MH, Glod CA (1990) Seasonal affective disorder: rapid resolution by low-dose alprazolam. Psychopharmacol Bull 26:197–202

    CAS  PubMed  Google Scholar 

  • Terman M, Terman JS, Quitkin FM et al (1989) Light therapy for seasonal affective disorder. A review of efficacy. Neuropsychopharmacol 2:1–22

    Article  CAS  Google Scholar 

  • Terman M, Amira L, Terman JS, Ross DC (1996) Predictors of response and nonresponse to light treatment for winter depression. Am J Psychiatry 153:1423–1429

    Article  CAS  PubMed  Google Scholar 

  • Tuunainen A, Kripke DF, Endo T (2004) Light therapy for non-seasonal depression. Cochrane Database Syst Rev Issue 2. Art No. CD004050

    Google Scholar 

  • Wehr TA, Skwerer RM, Jacobsen FM et al (1987) Eye-versus skin-phototherapy of seasonal affective disorder. Am J Psychiatry 144:753–757

    Article  CAS  PubMed  Google Scholar 

  • Willeit M, Sitte HH, Thierry N et al (2008) Enhanced serotonin transporter function during depression in seasonal affective disorder. Neuropsychopharmacol 33:1503–1513

    Article  CAS  Google Scholar 

  • Winkler D, Willeit M, Praschak-Rieder N et al (2002) Changes of clinical pattern in seasonal affective disorder (SAD) over time in a German-speaking sample. Eur Arch Psychiatry Clin Neurosci 252:54–62

    Article  CAS  PubMed  Google Scholar 

  • Winkler D, Pjrek E, Konstantinidis A, Kasper S (2009) Drug treatment of seasonal affective disorder. In: Partonen T, Pandi-Perumal SR (Hrsg) Seasonal affective disorder: practice and research, 2. Aufl. Oxford University Press, New York/Oxford, S 281–295

    Chapter  Google Scholar 

  • Wirz-Justice A, van der Velde P, Nil R (1992) Comparison of light treatment with citalopram in winter depression: a longitudinal single case study. Int Clin Psychopharmacol 7:109–116

    CAS  PubMed  Google Scholar 

  • Wirz-Justice A, Benedetti F, Berger M et al (2005) Chronotherapeutics (light and wake therapy) in affective disorders. Psychol Med 35:939–944

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Universitätsklinik für Psychiatrie und Psychotherapie, Medizinische Universität Wien AKH, Währinger Gürtel 18-20, 1090, Wien, Österreich

    Siegfried Kasper

Authors
  1. Siegfried Kasper
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Siegfried Kasper .

Editor information

Editors and Affiliations

  1. em. Direktor der Klinik für Psychiatrie und Psychotherapie, der Ludwig-Maximilians-Universität (LMU) München, München, Germany

    Hans-Jürgen Möller

  2. Ehem. Ärztlicher Direktor des kbo-Inn-Salzach-Klinikums für Psychiatrie, Psychotherapie, Psychosomatik und Neurologie, Akadem. Lehrkrankenhaus der LMU München Institut für Psychologische Medizin (IPM), Soyen, Germany

    Gerd Laux

  3. Vorstand der Klinik für Psychiatrie und Psychotherapeutische Medizin, Medizinische Universität Graz, Graz, Austria

    Hans-Peter Kapfhammer

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer-Verlag GmbH Deutschland

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Kasper, S. (2017). Lichttherapie. In: Möller, HJ., Laux, G., Kapfhammer, HP. (eds) Psychiatrie, Psychosomatik, Psychotherapie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49295-6_34

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-49295-6_34

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-49293-2

  • Online ISBN: 978-3-662-49295-6

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation