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Neurophysiologische Untersuchungsmethoden in der Psychiatrie

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Psychiatrie, Psychosomatik, Psychotherapie

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Zusammenfassung

Zu den neurophysiologischen Untersuchungsmethoden zählen die Elektroenzephalografie (EEG) und die ereigniskorrelierten Potenziale (EKP). Beide Verfahren sind in der Psychiatrie als nichtinvasive, funktionsdiagnostische Instrumente zur Abbildung neuronaler Massenaktivität unersetzbar. Sie liefern z. B. bei Demenzen wichtige diagnostische und differenzialdiagnostische Hinweise, sind zum Ausschluss epilepsietypischer Veränderungen obligat und erlauben die Erkennung neurotoxischer Reaktionen auf Psychopharmaka. Für spezielle Fragestellungen spielt außerdem die Schlafpolygrafie eine wichtige Rolle.

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Literatur

  • Adamis D, Sahu S, Treloar A (2005) The utility of EEG in dementia: a clinical perspective. Int J Geriatr Psychiatry 20:1038–1045

    Article  PubMed  Google Scholar 

  • Amann BL, Pogarell O, Mergl R et al (2003) EEG abnormalities associated with antipsychotics: a comparison of quetiapine, olanzapine, haloperidol and healthy subjects. Hum Psychopharmacol Clin Exp 18:641–646

    Article  CAS  Google Scholar 

  • Arendt G, Hefter H, Jablonowski H (1993) Acoustically evoked event-related potentials in HIV associated dementia. Electroencephalogr Clin Neurophysiol 86:152–160

    Article  CAS  PubMed  Google Scholar 

  • Babiloni C, Lizio R, Marzano N, Capotosto P, Soricelli A, Triggiani AI, Cordone S, Gesualdo L, Del Percio C (2015) Brain neural synchronization and functional coupling in Alzheimer’s disease as revealed by resting state EEG rhythms. Int J Psychophysiol. doi:10.1016/j.ijpsycho.2015.02.008. pii: S0167-8760(15)00038-0. (vor Druck)

  • Baldeweg T, Gruzelier JH, Catalan J et al (1993) Auditory visual event-related potentials in a controlled investigation of HIV infection. Electroencephalogr Clin Neurophysiol 88:356–368

    Article  CAS  PubMed  Google Scholar 

  • Basar-Eroglu C, Basar E, Demirralp T, Schurmann M (1992) The P300-response: possible psychophysiological correlates in delta and theta frequency channels. A review. Int J Psychophysiol 13:161–179

    Article  CAS  PubMed  Google Scholar 

  • Bauer G, Bauer R (1999) EEG, drug effects, and central nervous system poisoning. In: Niedermeyer E, da Silva Lopes FH (Hrsg) Electroencephalography: basic principles, clinical applications, and related fields, 4. Aufl. Williams and Wilkins, Baltimore, S 671–691

    Google Scholar 

  • Bellesi M, Passamonti L, Silvestrini M, Bartolini M, Provinciali L (2006) Non-convulsive status epilepticus during lithium treatment at therapeutic doses. Neurol Sci 26:444–446

    Article  CAS  PubMed  Google Scholar 

  • Benca RM, Obermeyer WH, Thisted RA, Gillin JC (1992) Sleep and psychiatric disorder. A meta-analysis. Arch Gen Psychiatry 49:651–668

    Article  CAS  PubMed  Google Scholar 

  • Bente D (1964) Vigilanz, dissoziative Vigilanzverschiebung und Insuffizienz des Vigilitätstonus. In: Kranz H, Heinrich K (Hrsg) Begleitwirkungen und Mißerfolge der psychiatrischen Pharmakotherapie. Thieme, Stuttgart, S 13–28

    Google Scholar 

  • Besson FL, La Joie R, Doeuvre L, Gaubert M, Mézenge F, Egret S, Landeau B, Barré L, Abbas A, Ibazizene M, de La Sayette V, Desgranges B, Eustache F, Chételat G (2015) Cognitive and brain profiles associated with current neuroimaging biomarkers of preclinical Alzheimer’s disease. J Neurosci 35:10402–10411

    Article  CAS  PubMed  Google Scholar 

  • Blackwood DH, St. Clair DM, Blackburn JM, Tyrer GM (1987a) Cognitive brain potentials and psychological deficits in Alzheimer’s dementia and Korsakoff’s amnestic syndrome. Psychol Med 17:349–358

    Article  CAS  PubMed  Google Scholar 

  • Blackwood DH, Whalley LJ, Christie JE et al (1987b) Changes in auditory P3 event-related potential in schizophrenia and depression. Br J Psychiatry 156:154–160

    Article  Google Scholar 

  • Blume WT, Young GB, Lemieux JF (1984) EEG morphology of partial epileptic seizures. Electroencephalogr Clin Neurophysiol 57:295–302

    Article  CAS  PubMed  Google Scholar 

  • Bortone E, Bettoni L, Giorgi C et al (1994) Reliability of EEG in the diagnosis of Creutzfeldt-Jakob disease. Electroencephalogr Clin Neurophysiol 90:323–330

    Article  CAS  PubMed  Google Scholar 

  • Bottlener R, Gallinat J, Moeller HJ, Hegerl U (1997) Effects of paroxetine on the quantitative EEG. Pharmacopsychiatry 30:155

    Google Scholar 

  • Boutros N, Galderisi S, Pogarell O, Riggio S (Hrsg) (2011) Standard electroencephalography in clinical psychiatry – a practical handbook. Wiley-Blackwell, Oxford, UK

    Google Scholar 

  • Brenner RP (1991) Utility of EEG in delirium: past views and current practice. Int Psychogeriatr 3:211–229

    Article  CAS  PubMed  Google Scholar 

  • Brenner RP, Ulrich RF, Spiker DG et al (1986) Computerized EEG spectral analysis in elderly normal, demented and depressed subjects. Electroencephalogr Clin Neurophysiol 64:483–492

    Article  CAS  PubMed  Google Scholar 

  • Brenner RP, Reynolds CF, Ulrich RF (1989) EEG findings in depressive pseudodementia and dementia with secondary depression. Electroencephalogr Clin Neurophysiol 72:298–304

    Article  CAS  PubMed  Google Scholar 

  • Briel RC, McKeith IG, Barker WA et al (1999) EEG findings in dementia with Lewy bodies and Alzheimer’s disease. J Neurol Neurosurg Psychiatry 66:401–403

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Brown DG, Goldensohn ES (1973) The electroencephalogram in normal pressure hydrocephalus. Arch Neurol 29:70–71

    Article  CAS  PubMed  Google Scholar 

  • Caso F, Cursi M, Magnani G, Fanelli G, Falautano M, Comi G, Leocani L, Minicucci F (2012) Quantitative EEG and LORETA: valuable tools in discerning FTD from AD. Neurobiol Aging 33:2343–2356

    Article  PubMed  Google Scholar 

  • Centorrino F, Price BH, Tuttle M et al (2002) EEG abnormalities during treatment with typical and atypical antipsychotics. Am J Psychiatry 159:109–115

    Article  PubMed  Google Scholar 

  • Chan D, Walters RJ, Sampson EL et al (2004) EEG abnormalities in frontotemporal lobar degeneration. Neurology 62:1628–1630

    Article  CAS  PubMed  Google Scholar 

  • Charles G, Hansenne M (1992) Le potentiel lent P300. Encéphale 18:225–236

    CAS  PubMed  Google Scholar 

  • Coben LA, Danziger W, Storandt M (1985) A longitudinal EEG study of mild senile dementia of Alzheimer type: changes at 1 year and at 2.5 years. Electroencephalogr Clin Neurophysiol 61:101–112

    Article  CAS  PubMed  Google Scholar 

  • Coben LA, Chi D, Snyder AZ, Storandt M (1990) Replication of a study of frequency analysis of the resting awake EEG in mild probable Alzheimer’s disease. Electroencephalogr Clin Neurophysiol 75:148–154

    Article  CAS  PubMed  Google Scholar 

  • Connolly S, Manji H, McAllister RH et al (1994) Long-latency event-related potentials in asymptomatic human immunodeficiency virus 1 infection. Ann Neurol 35:189–196

    Article  CAS  PubMed  Google Scholar 

  • Corsi-Cabrera M, Munoz-Torres Z, Rio-Portilla Y, Guevara MA (2006) Power and coherent oscillations distinguish REM sleep, stage 1 and wakefulness. Int J Psychophysiol 60:59–66

    Article  CAS  PubMed  Google Scholar 

  • Cromarty RA, Elder GJ, Graziadio S, Baker M, Bonanni L, Onofrj M, O’Brien JT, Taylor JP (2015) Neurophysiological biomarkers for Lewy body dementias. Clin Neurophysiol. doi:10.1016/j.clinph.2015.06.020. pii: S1388 2457(15)00676-8. (vor Druck)

  • Dammers S, Zeit T, Leonhardt M, Schar V, Agelink MW (1995) Malignes neuroleptisches Syndrom. Dtsch Med Wochenschr 120:1739–1742

    Article  CAS  PubMed  Google Scholar 

  • David O, Kiebel SJ, Harrison LM, Mattout J, Kilner JM, Friston KJ (2006) Dynamic causal modeling of evoked responses in EEG and MEG. Neuroimage 30:1255–1272

    Article  PubMed  Google Scholar 

  • De Santi S, de Leon MJ, Rusinek H et al (2001) Hippocampal formation glucose metabolism and volume losses in MCI and AD. Neurobiol Aging 22:529–539

    Article  PubMed  Google Scholar 

  • Dement W, Kleitman N (1957) Cyclic variations in EEG during sleep and their relation to eye movements, body motality, and dreaming. Electroencephalogr Clin Neurophysiol 9:673–690

    Article  CAS  PubMed  Google Scholar 

  • Desmedt JE, Tomberg C (1994) Transient phase-locking of 40 Hz electrical oscillations in prefrontal and parietal human cortex reflects the process of conscious somatic perception. Neurosci Lett 168:126–129

    Article  CAS  PubMed  Google Scholar 

  • Diner BC, Holocomb PJ, Dykman RA (1985) P300 in major depression disorder. Psychiatry Res 15:175–184

    Article  CAS  PubMed  Google Scholar 

  • Eickhoff SB, Grefkes C (2011) Systemtheorie und Dynamic Causal Modelling. In: Schiepek G (Hrsg) Neurobiologie der Psychotherapie. Schattauer, Stuttgart

    Google Scholar 

  • Elovaara I, Saar P, Valle SL et al (1991) EEG in early HIV-1 infection is characterized by anterior dysrhythmicity of low maximal amplitude. Clin Electroencephalogr 22:131–140

    Article  CAS  PubMed  Google Scholar 

  • Engel AK, Singer W (2001) Temporal binding and the neural correlates of sensory awareness. Trends Cogn Sci 5:16–25

    Article  PubMed  Google Scholar 

  • Ereshefsky L, Watanabe MD, Tran-Johnson TK (1989) Clozapine: an atypical antipsychotic agent. Clin Pharm 8:691–707

    CAS  PubMed  Google Scholar 

  • Erkinjuntti T, Larsen T, Sulkava R et al (1988) EEG in differential diagnosis between Alzheimer’s disease and vascular dementia. Acta Neurol Scand 77:36–43

    Article  CAS  PubMed  Google Scholar 

  • Förstl H, Besthorn C, Hentschel F et al (1996) Frontal lobe degeneration and Alzheimer’s disease: a controlled study on clinical findings, volumetric brain changes and quantitative electroencephalography data. Dementia 7:27–34

    PubMed  Google Scholar 

  • Friston KJ, Harrison L, Penny W (2003) Dynamic causal modelling. Neuroimage 19:1273–1302

    Article  CAS  PubMed  Google Scholar 

  • Garn H, Waser M, Deistler M, Schmidt R, Dal-Bianco P, Ransmayr G, Zeitlhofer J, Schmidt H, Seiler S, Sanin G, Caravias G, Santer P, Grossegger D, Fruehwirt W, Benke T (2014) Quantitative EEG in Alzheimer’s disease: cognitive state, resting state and association with disease severity. Int J Psychophysiol 93:390–397

    Article  PubMed  Google Scholar 

  • Gawel M, Zalewska E, Szmidt-Sałkowska E, Kowalski J (2009) The value of quantitative EEG in differential diagnosis of Alzheimer’s disease and subcortical vascular dementia. J Neurol Sci 283:127–133

    Article  CAS  PubMed  Google Scholar 

  • Geissler J, Romanos M, Hegerl U, Hensch T (2014) Hyperactivity and sensation seeking as autoregulatory attempts to stabilize brain arousal in ADHD and mania? Atten Defic Hyperact Disord 6:159–173

    Article  PubMed  Google Scholar 

  • Goodin DS (1990) Clinical utility of long latency „cognitive“ event-related potentials (P3): the pros. Electroencephalogr Clin Neurophysiol 76:2–5

    Article  CAS  PubMed  Google Scholar 

  • Goodin DS, Aminoff MJ (1986) Eletrophysiological differences between subtypes of dementia. Brain 109:1103–1113

    Article  PubMed  Google Scholar 

  • Grossmann WM, Standl A, May U et al (1990) Naftidrofuryl in the treatment of mild senile dementia. A double blind study. Pharmacopsychiatry 23:265–273

    Article  CAS  PubMed  Google Scholar 

  • Guberman A, Cantu-Reyna G, Stuss D, Broughton R (1986) Nonconvulsive generalized status epilepticus: clinical features, neuropsychological testing, and long-term follow-up. Neurology 36:1284–1291

    Article  CAS  PubMed  Google Scholar 

  • Günther W, Baghai T, Naber D et al (1993) EEG alterations and seizures during treatment with clozapine. A retrospective study of 283 patients. Pharmacopsychiatry 26:69–74

    Article  PubMed  Google Scholar 

  • Gustafson L, Brun A, Risberg J (Hrsg) (1990) Frontal lobe dementia of non-Alzheimer type. Raven, New York, S 65–71

    Google Scholar 

  • Hampel H, Teipel SJ, Alexander GE et al (2002) In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer’s disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EEG and PET. J Neural Transm 109:837–855

    Article  CAS  PubMed  Google Scholar 

  • Hansen N, Finzel M, Block F (2010) Antiepileptic drug-induced encephalopathy. Fortschr Neurol Psychiatr 78:590–598

    Article  CAS  PubMed  Google Scholar 

  • Hayashi R, Umikawa N, Kajiki N et al (1996) The effects of alprazolam over time on both event-related potential (P300) and choice reaction time. In: Ogura C, Koga Y, Shimokochi M (Hrsg) Recent advances in event-related brain potential research. Elsevier Science, Amsterdem, S 660–664

    Google Scholar 

  • Hedges D, Janis R, Mickelson S, Keith C, Bennett D, Brown BL (2016) P300 amplitude in Alzheimer’s disease: a meta analysis and meta-regression. Clin EEG Neurosci 47:48–55

    Google Scholar 

  • Hegerl U (Hrsg) (1998) Neurophysiologische Untersuchungen in der Psychiatrie – EEG, EKP, Schlafpolygraphie, Motorik, autonome Funktionen. Springer, Wien/New York

    Google Scholar 

  • Hegerl U, Frodl-Bauch T (1997) Dipole source analysis of auditory evoked P300: a methodological advance? Psychiatry Res: Neuroimaging 74:109–118

    Article  CAS  PubMed  Google Scholar 

  • Hegerl U, Hensch T (2014) The vigilance regulation model of affective disorders and ADHD. Neurosci Biobehav Rev 44:45–57

    Article  PubMed  Google Scholar 

  • Hegerl U, Juckel G (1993) Konstruktivismus und Psychiatrie. In: Danzer G, Priebe S (Hrsg) Forschen und Denken – Wege in der Psychiatrie. Königshausen & Neumann, Würzburg, S 121–141

    Google Scholar 

  • Hegerl U, Juckel G, Müller-Schubert A et al (1995) Schizophrenics with small P300: a subgroup with neurodevelopmental disturbance and a high risk for tardive dyskinesia? Acta Psychiatr Scand 91:120–125

    Article  CAS  PubMed  Google Scholar 

  • Hegerl U, Juckel G, Möller H-J (1996) Ereigniskorrelierte Hirnpotentiale als Indikatoren neurochemischer Dysfunktionen bei psychiatrischen Patienten. Nervenarzt 67:360–368

    CAS  PubMed  Google Scholar 

  • Hegerl U, Bottlender R, Gallinat J et al (1998) The serotonin syndrome scale: first results on validity. Eur Arch Psychiatry Neurol Sci 248:96–103

    Article  CAS  Google Scholar 

  • Hegerl U, Stein M, Mulert C et al (2008) EEG-vigilance differences between patients with borderline personality disorder, patients with obsessive-compulsive disorder and healthy controls. Eur Arch Psychiatry Clin Neurosci 258:137–143

    Article  PubMed  Google Scholar 

  • Hegerl U, Sander C, Olbrich S, Schönknecht P (2009) Are psychostimulants a treatment option in mania? Pharmacopsychiatry 42:169–174

    Article  CAS  PubMed  Google Scholar 

  • Hegerl U, Himmerich H, Engmann B, Hensch T (2010) Mania and attention-deficit/hyperactivity disorder: common symptomatology, common pathophysiology and common treatment? Curr Opin Psychiatry 23:1–7

    Article  PubMed  Google Scholar 

  • Hegerl U, Wilk K, Olbrich S, Schoenknecht P, Sander C (2012) Hyperstable regulation of vigilance in patients with major depressive disorder. World J Biol Psychiatry Off J World Fed Soc Biol Psychiatry 13(6):436–446

    Article  Google Scholar 

  • Heiss WD, Kessler J, Mielke R et al (1994) Long-term effects of phosphatidylserine, pyritinol, and cognitive training in Alzheimer’s disease. A neuropsychological, EEG, and PET investigation. Dementia 5:88–98

    CAS  PubMed  Google Scholar 

  • Hogh P, Smith SJ, Scahill RI et al (2002) Epilepsy presenting as AD: neuroimaging, electroclinical features, and response to treatment. Neurology 58:298–301

    Article  CAS  PubMed  Google Scholar 

  • Howe AS, Bani-Fatemi A, De Luca V (2014) The clinical utility of the auditory P300 latency subcomponent event-related potential in preclinical diagnosis of patients with mild cognitive impairment and Alzheimer’s disease. Brain Cogn 86:64–74

    Article  PubMed  Google Scholar 

  • Ihl R, Maurer K, Dierks T, Wannemacher W (1988) Effects of pyritinol on the distribution of electric brain activity. Pharmacopsychiatry 21:343–345

    Article  CAS  PubMed  Google Scholar 

  • Iwanami A, Fujishima T, Iritani S et al (1993) Effects of nicergoline on the P300 component of event-related potentials in demented patients. Neurol Psychiatry Brain Res 1:232–234

    Google Scholar 

  • Jelic V, Kowalski J (2009) Evidence-based evaluation of diagnostic accuracy of resting EEG in dementia and mild cognitive impairment. Clin EEG Neurosci 40:129–142

    Article  PubMed  Google Scholar 

  • Jelic V, Wahlund LO (2007) Diagnostic imaging devices in Alzheimer’s disease. Expert Rev Med Devices 4:475–487

    Article  PubMed  Google Scholar 

  • Johnson RT, Gibbs CJ (1998) Creutzfeldt-Jakob disease and related transmissible spongiform encephalopathies. N Engl J Med 339:1994–2004

    Article  CAS  PubMed  Google Scholar 

  • Jokeit H, Makeig S (1994) Different event-related patterns of gamma-band power in brain waves of fast- and slow-reacting subjects. Proc Natl Acad Sci U S A 91:6339–6343

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Juckel G (2003) Effekte von Psychopharmaka auf das EEG. Neurophysiol Lab 25:89–105

    Google Scholar 

  • Juckel G, Müller-Schubert A, Gaebel W, Hegerl U (1997) Residual symptoms and P300 in schizophrenic outpatients. Psychiatry Res 65:23–32

    Article  Google Scholar 

  • Julin P, Wahlund LO, Basun H et al (1995) Clinical diagnosis of frontal lobe dementia and Alzheimer’s disease: relation to cerebral perfusion, brain atrophy and electroencephalography. Dementia 6:142–147

    CAS  PubMed  Google Scholar 

  • Kaplan PW (1999) Assessing the outcomes in patients with nonconvulsive status epilepticus: nonconvulsive status epilepticus is underdiagnosed, potentially overtreated, and confounded by comorbidity. J Clin Neurophysiol 16:341–352

    Article  CAS  PubMed  Google Scholar 

  • Karch S, Hegerl U, Pogarell O (2014) Elektroenzephalographie. In: Gruber O, Falkai P (Hrsg) Systemische Neurowissenschaften in der Psychiatrie. Kohlhammer, Stuttgart, S 153–176

    Google Scholar 

  • Kiebel SJ, Garrido MI, Moran R, Chen CC, Friston KJ (2009) Dynamic causal modeling for EEG and MEG. Hum Brain Mapp 30:1866–1876

    Article  PubMed  Google Scholar 

  • Kiloh LG, McComas AJ, Osselton JW (1972) Clinical electroencephalography, 3. Aufl. Butterworth, London

    Google Scholar 

  • Koralnik J, Beaumanoir A, Hausler A et al (1990) A controlled study of early neurologic abnormalities in man with asymptomatic human immundeficiency virus infection. N Engl J Med 323:864–870

    Article  CAS  PubMed  Google Scholar 

  • Lee H, Brekelmans GJ, Roks G (2015) The EEG as a diagnostic tool in distinguishing between dementia with Lewy bodies and Alzheimer’s disease. Clin Neurophysiol 126: 1735–1739

    Google Scholar 

  • Leuchter AF, Spar JE, Walter DO, Weiner H (1987) Electroencephalographic spectra and coherence in the diagnosis of Alzheimer’s-type and multi-infarct dementia. Arch Gen Psychiatry 44:993–998

    Article  CAS  PubMed  Google Scholar 

  • Lindau M, Jelic V, Johansson SE et al (2003) Quantitative EEG abnormalities and cognitive dysfunctions in frontotemporal dementia and Alzheimer’s disease. Dement Geriatr Cogn Disord 15:106–114

    Article  CAS  PubMed  Google Scholar 

  • Llinas RR, Steriade M (2006) Bursting of thalamic neurons and states of vigilance. J Neurophysiol 95:3297–3308

    Article  PubMed  Google Scholar 

  • Logar C, Grabmair W, Schneider G, Lechner H (1987) EEG-Veränderungen bei seniler Demenz vom Alzheimer Typ. Z EEG-EMG 18:214–216

    CAS  Google Scholar 

  • Loomis AL, Harvey EN, Hobart GA (1937) Cerebral states during sleep as studied by human brain potentials. J Exp Psychol 21:127–144

    Article  Google Scholar 

  • Maurer K, Dierks T (1992) Functional imaging procedures in dementias: mapping of EEG and evoked potentials. Acta Neurol Scand Suppl 139:40–46

    Article  CAS  PubMed  Google Scholar 

  • Messenheimer JA, Robertson KR, Wilkins JW et al (1992) Event-related potentials in human immunodeficiency virus infection. A prospective study. Arch Neurol 49:396–400

    Article  CAS  PubMed  Google Scholar 

  • Mitsuyama Y (1993) Presenile dementia with motor neuron disease. Dementia 4:137–142

    CAS  PubMed  Google Scholar 

  • Mosconi L, De Santi S, Rusinek H et al (2004) Magnetic resonance and PET studies in the early diagnosis of Alzheimer’s disease. Expert Rev Neurother 4:831–849

    Article  PubMed  Google Scholar 

  • Mulert C, Gallinat J, Pascual-Marqui R et al (2001) Reduced event-related current density in the anterior cingulate cortex in schizophrenia. Neuroimage 13:589–600

    Article  CAS  PubMed  Google Scholar 

  • Mulert C, Jager L, Schmitt R et al (2004a) Integration of fMRI and simultaneous EEG: towards a comprehensive understanding of localization and time-course of brain activity in target detection. Neuroimage 22:83–94

    Article  PubMed  Google Scholar 

  • Mulert C, Pogarell O, Juckel G et al (2004b) The neural basis of the P300 potential. Focus on the time-course of the underlying cortical generators. Eur Arch Psychiatry Clin Neurosci 254:190–198

    Article  CAS  PubMed  Google Scholar 

  • Mulert C, Jager L, Propp S et al (2005) Sound level dependence of the primary auditory cortex: simultaneous measurement with 61-channel EEG and fMRI. Neuroimage 28:49–58

    Article  PubMed  Google Scholar 

  • Naka D, Maeshima S, Mizushima A et al (1996) Changes in P300 latency in normal pressure hydrocephalus before and after ventriculo-peritoneal shunt. In: Ogura C, Koga Y, Shimokochi M (Hrsg) Recent advances in event-related brain potential research. Elsevier Science, Amsterdam, S 452–456

    Google Scholar 

  • Neary D, Snowden JS, Gustafson L et al (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546–1554

    Article  CAS  PubMed  Google Scholar 

  • Neto E, Allen EA, Aurlien H, Nordby H, Eichele T (2015) EEG spectral features discriminate between Alzheimer’s and vascular dementia. Front Neurol. doi:10.3389/fneur.2015.00025. eCollection 2015

  • Newman SE (1978) The EEG manifestations of chronic ethanol abuse: relation to cerebral cortical atrophy. Ann Neurol 3:299–304

    Article  CAS  PubMed  Google Scholar 

  • Nishida K, Yoshimura M, Isotani T, Yoshida T, Kitaura Y, Saito A, Mii H, Kato M, Takekita Y, Suwa A, Morita S, Kinoshita T (2011) Differences in quantitative EEG between frontotemporal dementia and Alzheimer’s disease as revealed by LORETA. Clin Neurophysiol 122:1718–1725

    Article  CAS  PubMed  Google Scholar 

  • Olbrich S, Mulert C, Karch S, Trenner M, Leicht G, Pogarell O, Hegerl U (2009) EEG-vigilance and BOLD effect during simultaneous EEG/fMRI measurement. Neuroimage 45:319–332

    Article  PubMed  Google Scholar 

  • Ollo C, Johnson R Jr, Grafman J (1991) Signs of cognitive change in HIV disease: an event-related brain potential study. Neurology 41:209–215

    Article  CAS  PubMed  Google Scholar 

  • Onofrj M, Thomas A, Luciano AL et al (2002) Donepezil versus vitamin E in Alzheimer’s disease: part 2: mild versus moderate severe Alzheimer’s disease. Clin Neuropharmacol 25:207–215

    Article  PubMed  Google Scholar 

  • Parisi A (1989) Neurophysiological diagnosis of AIDS dementia complex: importance of electroencephalography. G Ital Med Lav 11:19–21

    CAS  PubMed  Google Scholar 

  • Parisi A, DiPerri G, Stosselli M et al (1989) Usefullness of computerized electroencephalography in diagnosing, staging and monitoring AIDS-dementia complex. AIDS 3:209–213

    Article  CAS  PubMed  Google Scholar 

  • Pascual-Marqui RD, Michel CM, Lehmann D (1994) Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. Int J Psychophysiol 18:49–65

    Article  CAS  PubMed  Google Scholar 

  • Penttitilä M, Partanen JV, Soininen H, Riekkinen PJ (1985) Quantitative analysis of occipital EEG in different stages of Alzheimer’s disease. Electroencephalogr Clin Neurophysiol 60:1–6

    Article  Google Scholar 

  • Perrin RJ, Fagan AM, Holtzman DM (2009) Multimodal techniques for diagnosis and prognosis of Alzheimer’s disease. Nature 461:916–922

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pfefferbaum A, Ford JM, Kraemer HC (1990) Clinical utility of long latency „cognitive“ event-related potentials (P3): the cons. Electroencephalogr Clin Neurophysiol 76:6–12

    Article  CAS  PubMed  Google Scholar 

  • Pijnenburg YA, Strijers RL, Made YV et al (2008) Investigation of resting-state EEG functional connectivity in frontotemporal lobar degeneration. Clin Neurophysiol 119:1732–1738

    Article  PubMed  Google Scholar 

  • Pizzagalli D, Pascual-Marqui RD, Nitschke JB et al (2001) Anterior cingulate activity as a predictor of degree of treatment response in major depression: evidence from brain electrical tomography analysis. Am J Psychiatry 158:405–415

    Article  CAS  PubMed  Google Scholar 

  • Pogarell O, Hegerl U (2003) Neurophysiologische Verfahren in der Diagnostik und Differenzialdiagnostik demenzieller Syndrome. Klin Neurophysiol 34:49–54

    Article  Google Scholar 

  • Pogarell O, Hegerl U (2004) Electric brain activity in psychiatry: research tools with clinical value. In: Moore NC, Arikan MK (Hrsg) Brainwaves and mind: recent advances. A report from Istanbul. Kjellberg, Inc., Wheaton

    Google Scholar 

  • Pogarell O, Schulz C, Juckel G et al (2001) Auditory evoked P300 and treatment response to donepezil in patients with Alzheimer’s disease. World J Biol Psychiatry 2:264

    Google Scholar 

  • Pogarell O, Juckel G, Mulert C et al (2004) EEG abnormalities under treatment with atypical antipsychotics: effects of olanzapine and amisulpride as compared to haloperidol. Pharmacopsychiatry 37:304–305

    Article  CAS  PubMed  Google Scholar 

  • Pogarell O, Ehrentraut S, Ruther T et al (2005a) Prolonged confusional state following electroconvulsive therapy – diagnostic clues from serial electroencephalography. Pharmacopsychiatry 38:316–320

    Article  CAS  PubMed  Google Scholar 

  • Pogarell O, Teipel SJ, Juckel G et al (2005b) EEG coherence reflects regional corpus callosum area in Alzheimer’s disease. J Neurol Neurosurg Psychiatry 76:109–111

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pogarell O, Hegerl U, Boutros N (2005c) Clinical neurophysiology services in psychiatry departments. Psychiatr Serv 56:871

    Article  PubMed  Google Scholar 

  • Pogarell O, Hegerl U, Mulert C (2006a) Electroconvulsive therapy and nonconvulsive status epilepticus – response to anticonvulsants might solve the dilemma. Pharmacopsychiatry 39:120

    Article  Google Scholar 

  • Pogarell O, Folkerts M, Hegerl U (2006b) Adverse neurological and neurotoxic effects of lithium therapy. In: Bauer M, Grof P, Müller-Oerlinghausen B, in collaboration with The International Group for the Study of Lithium-Treated Patients (IGSLi) (Hrsg) Lithium in neuropsychiatry: the comprehensive guide. Taylor and Francis Books Ltd., London, S 271–282

    Chapter  Google Scholar 

  • Pogarell O, Hensch T, Hegerl U (2012) Elektroenzephalographie in der Psychopharmakotherapie. In: Gründer G, Benkert O (Hrsg) Handbuch der Psychopharmakotherapie, 2. Aufl. Springer, Berlin, S 399–415

    Chapter  Google Scholar 

  • Polich J, Ladish C, Bloom FE (1990) P300 assessment of early Alzheimer’s disease. Electroencephalogr Clin Neurophysiol 77:179–189

    Article  CAS  PubMed  Google Scholar 

  • Polikar R, Tilley C, Hillis B, Clark CM (2010) Multimodal EEG, MRI and PET data fusion for Alzheimer’s disease diagnosis. Conf Proc IEEE Eng Med Biol Soc 2010:6058–6061

    PubMed  Google Scholar 

  • Pollock VE, Schneider LS, Chui HC et al (1989) Visual evoked potentials in dementia: a meta analysis and empirical study of Alzheimer’s disease patients. Biol Psychiatry 25:1003–1013

    Article  CAS  PubMed  Google Scholar 

  • Povlsen UJ, Wildschiodtz G, Hogenhaven H, Bolwig TG (2003) Nonconvulsive status epilepticus after electroconvulsive therapy. J ECT 19:164–169

    Article  PubMed  Google Scholar 

  • Prinz PN, Vitiello MV (1989) Dominant occipital (alpha) rhythm frequency in early stage of Alzheimer’s disease and depression. Electroencephalogr Clin Neurophysiol 73:427–432

    Article  CAS  PubMed  Google Scholar 

  • Purdie FR, Hareginin B, Rosen P (1981) Acute organic brain syndrome: review of 100 cases. Ann Emerg Med 10:455–461

    Article  CAS  PubMed  Google Scholar 

  • Ragazzoni A, Grippo A, Ghidini P et al (1993) Electrophysiological study of neurologically asymptomatic HIV1 seropositive patients. Acta Neurol Scand 87:47–51

    Article  CAS  PubMed  Google Scholar 

  • Rechtschaffen A, Kales A (1968) A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. US Government Printing Office, Public Health Service, Washington, DC

    Google Scholar 

  • Revuelta E, Bordet R, Piquet T et al (1994) Catatonie aigue et syndrome malin des neuroleptiques. Un cas au cours d’une psychose infantile. Encéphale 20:351–354

    CAS  PubMed  Google Scholar 

  • Robinson DJ, Merskey H, Blume WT et al (1994) Electroencephalography as an aid in the exclusion of Alzheimer’s disease. Arch Neurol 51:280–284

    Article  CAS  PubMed  Google Scholar 

  • Rockstroh B, Elbert T, Lutzenberger W, Altenmüller E (1991) Effects of the anticonvulsant benzodiazepine clonazepam on event-related brain potentials in humans. Electroencephalogr Clin Neurophysiol 78:142–149

    Article  CAS  PubMed  Google Scholar 

  • Roks G, Korf ES, van der Flier WM, Scheltens P, Stam CJ (2008) The use of EEG in the diagnosis of dementia with Lewy bodies. J Neurol Neurosurg Psychiatry 79:377–380

    Article  CAS  PubMed  Google Scholar 

  • Rosebush P, Stewart T (1989) A prospective analysis of 24 episodes of neuroleptic malignant syndrome. Am J Psychiatry 146:717–725

    Article  CAS  PubMed  Google Scholar 

  • Rosén I, Gustafson L, Risberg J (1993) Multichannel EEG frequency analysis and somatosensory-evoked potentials in patients with different types of organic dementia. Dementia 4:43–49

    PubMed  Google Scholar 

  • Rossini PM, Del Percio C, Pasqualetti P et al (2006) Conversion from mild cognitive impairment to Alzheimer’s disease is predicted by sources and coherence of brain electroencephalography rhythms. Neuroscience 143:793–803

    Article  CAS  PubMed  Google Scholar 

  • Roth B (1961) The clinical and theoretical importance of EEG rhythms corresponding to states of lowered vigilance. Electroencephalogr Clin Neurophysiol 13:395–399

    Article  CAS  PubMed  Google Scholar 

  • Saletu B, Paulus E, Linzmayer L et al (1995) Nicergoline in senile dementia of Alzheimer type and multi-infarct dementia: a double-blind, placebo-controlled, clinical and EEG/ERP mapping study. Psychopharmacology (Berl) 117:385–395

    Article  CAS  Google Scholar 

  • Scherg M (1991) Akustisch evozierte Potentiale. Kohlhammer, Stuttgart

    Google Scholar 

  • Schroeder MU, Handelsman L, Torres L et al (1994) Early and late cognitive event-related potentials mark stages of HIV-1 infections in drug user risk group. Biol Psychiatry 35:54–69

    Article  CAS  PubMed  Google Scholar 

  • Segura-Bruna N, Rodriguez Campello A, Puente V, Roquer J (2006) Valproate-induced hyperammonemic encephalopathy. Acta Neurol Scand 114:1–7

    Article  CAS  PubMed  Google Scholar 

  • Signorino M, Pucci E, Belardinelli N et al (1995) EEG spectral analysis in vascular and Alzheimer dementia. Electroencephalogr Clin Neurophysiol 94:313–325

    Article  CAS  PubMed  Google Scholar 

  • Sloan EP, Fenton GW (1993) EEG power spectra and cognitive change in geriatric psychiatry: a longitudinal study. Electroencephalogr Clin Neurophysiol 86:361–367

    Article  CAS  PubMed  Google Scholar 

  • Small JG, Milstein V, Malloy FW et al (1999) Clinical and quantitative EEG studies of mania. J Affect Disord 53:217–224

    Article  CAS  PubMed  Google Scholar 

  • Smith SJ, Kocen RS (1988) A Creutzfeldt-Jakob like syndrome due to lithium toxicity. J Neurol Neurosurg Psychiatry 51:120–123

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • So EL (2010) Interictal epileptiform discharges in persons without a history of seizures: what do they mean? J Clin Neurophysiol 27:229–238

    Article  PubMed  Google Scholar 

  • Soininen H, Partanen J, Paakkonen A et al (1991) Changes in absolute power values of EEG spectra in the follow-up of Alzheimer’s disease. Acta Neurol Scand 83:133–136

    Article  CAS  PubMed  Google Scholar 

  • Soininen H, Reinikainen KJ, Partanen J et al (1992) Slowing of electroencephalogram and choline acetyltransferase activity in post mortem frontal cortex in definite Alzheimer’s disease. Neuroscience 49:529–535

    Article  CAS  PubMed  Google Scholar 

  • Squires K, Goodin D, Starr A (1979) Event related potentials in development, aging and dementia. In: Lehmann D, Callaway E (Hrsg) Human evoked potentials. Plenum, New York, S 383–396

    Chapter  Google Scholar 

  • St. Clair DM, Blackwood DH, Christie JH (1985) P3 and other long latency auditory evoked potentials in presenile dementia of Alzheimer type and alcoholic Korsakoff syndrome. Biol Psychiatry 147:702–706

    CAS  Google Scholar 

  • Steinhoff BJ, Kropp S, Riedemann C et al (1998) Elektroenzephalografische Charakteristika der Creutzfeldt-Jakobschen Krankheit und ihre Differentialdiagnose. Fortschr Neurol Psychiatr 66:357–365

    Article  CAS  PubMed  Google Scholar 

  • Sterr A, Padberg F, Amann B et al (2006) EEG abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine and amitriptyline. J Clin Psychiatry 67:325–326

    Article  PubMed  Google Scholar 

  • Stigsby B, Johannesson G, Ingvar DM (1981) Regional EEG analysis and regional cerebral blood flow in Alzheimer’s and Pick’s diseases. Electroencephalogr Clin Neurophysiol 51:537–547

    Article  CAS  PubMed  Google Scholar 

  • Striano S, Vacca G, Bilo L, Meo R (1981) The electroencephalogram in dementia: differential diagnostic value in Alzheimer’s disease, senile dementia and multi-infarct dementia. Acta Neurol (Napoli) 36:727–734

    Google Scholar 

  • Sundaram M, Hogan T, Hiscock M, Pillay N (1990) Factors affecting interictal spike discharges in adults with epilepsy. Electroencephalogr Clin Neurophysiol 75:358–360

    Article  CAS  PubMed  Google Scholar 

  • Tatum WO IV, Ross J, Cole AJ (1998) Epileptic pseudodementia. Neurology 50:1472–1475

    Article  PubMed  Google Scholar 

  • Tatum WO IV, French JA, Benbadis SR, Kaplan PW (2001) The etiology and diagnosis of status epilepticus. Epilepsy Behav 2:311–317

    Article  Google Scholar 

  • Teipel SJ, Pogarell O, Meindl T et al (2009) Regional networks underlying interhemispheric connectivity: an EEG and DTI study in healthy ageing and amnestic mild cognitive impairment. Hum Brain Mapp 30:2098–2119

    Article  PubMed  Google Scholar 

  • Thier P, Axmann D, Giedke H (1986) Slow brain potentials and psychomotor retardation in depression. Electroencephalogr Clin Neurophysiol 63:570–581

    Article  CAS  PubMed  Google Scholar 

  • Thomas A, Iacono D, Bonanni L et al (2001) Donepezil, rivastigmine, and vitamin E in Alzheimer disease: a combined P300 event-related potentials/neuropsychologic evaluation over 6 months. Clin Neuropharmacol 24:31–42

    Article  CAS  PubMed  Google Scholar 

  • Turven HF, Penin H (1992) Elektroenzephalographische Befunde bei dementiellen Krankheitsbildern. Fortschr Neurol Psychiatr 60:460–470

    Article  Google Scholar 

  • Ulrich G (1994) Psychiatrische Elektroenzephalographie. Fischer, Jena

    Google Scholar 

  • Ulrich G, Fürstenberg U (1999) Quantitative assessment of dynamic electroencephalogram (EEG) organization as a tool for subtyping depressive syndromes. Eur Psychiatry 14:217–229

    Article  CAS  PubMed  Google Scholar 

  • Van Deursen JA, Vuurman EF, Verhey FR et al (2008) Increased EEG gamma band activity in Alzheimer’s disease and mild cognitive impairment. J Neural Transm 115:1301–1311

    Article  PubMed  PubMed Central  Google Scholar 

  • Vanderwolf CH (1992) The electrocorticogramm in relation to physiology and behavior: a new analysis. Electroencephalogr Clin Neurophysiol 82:165–175

    Article  CAS  PubMed  Google Scholar 

  • Ware JC (1989) Monitoring erections during sleep. In: Kryger MH, Roth T, Dement WC (Hrsg) Principles and practice of sleep medicine. Saunders, Philadelphia, S 689–695

    Google Scholar 

  • Wiegand M (1995) Erektile Dysfunktion: Diagnostische Möglichkeiten des Schlaflabors. Sexuologie 2:90–96

    Google Scholar 

  • Wirrell EC (2010) Prognostic significance of interictal epileptiform discharges in newly diagnosed seizure disorders. J Clin Neurophysiol 27:239–248

    Article  PubMed  Google Scholar 

  • Wong J, Delva N (2007) Clozapine-induced seizures: recognition and treatment. Can J Psychiatry 52:457–463

    Article  PubMed  Google Scholar 

  • Zerr I, Pocchiari M, Collins S et al (2000a) Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt-Jakob disease. Neurology 55:811–815

    Article  CAS  PubMed  Google Scholar 

  • Zerr I, Schulz-Schaeffer WJ, Giese A et al (2000b) Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants. Ann Neurol 48:323–329

    Article  CAS  PubMed  Google Scholar 

  • Zschocke S (1995) Klinische Elektroenzephalographie. Springer, Berlin/Heidelberg/New York/Tokio

    Google Scholar 

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Pogarell, O., Hegerl, U. (2017). Neurophysiologische Untersuchungsmethoden in der Psychiatrie. In: Möller, HJ., Laux, G., Kapfhammer, HP. (eds) Psychiatrie, Psychosomatik, Psychotherapie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49295-6_28

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