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Polymeric Nanocapsules for Topical Delivery

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Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement

Abstract

Polymeric nanocapsules represent an interesting carrier system for cutaneous applications. The possibilities of modulating skin penetration/permeation by altering the design of the formulation and the range of applicability are the main subjects under study. With this in mind, this chapter will address methods of nanocapsule preparation and the influence of the polymeric wall, the surface functionalization, and the vehicle on the skin penetration/permeation profile of active substances loaded in polymeric nanocapsules. Additionally, therapeutic and cosmetic applications of nanocapsules will also be discussed.

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Acknowledgments

The authors thank the Brazilian public agencies (CNPq/MCTI, FINEP, CAPES, and FAPERGS) for financial support.

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Authors and Affiliations

  1. Departamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio Grande do Sul, Av Bento Gonçalves 9500, 15003, Porto Alegre, 91501-970, Brazil

    Adriana R. Pohlmann

  2. Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Av. Ipiranga 2752, Porto Alegre, 90610-000, Brazil

    Adriana R. Pohlmann, Cassia B. Detoni, Karina Paese, Karine Coradini, Ruy C. R. Beck & Sílvia S. Guterres

Authors
  1. Adriana R. Pohlmann
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  2. Cassia B. Detoni
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  3. Karina Paese
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  4. Karine Coradini
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  5. Ruy C. R. Beck
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  6. Sílvia S. Guterres
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Corresponding author

Correspondence to Adriana R. Pohlmann .

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Editors and Affiliations

  1. Department of Manufacturing, Apoteka "Beograd", Belgrade, Serbia

    Nina Dragicevic

  2. San Francisco, California, USA

    Howard I. Maibach

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Pohlmann, A.R., Detoni, C.B., Paese, K., Coradini, K., Beck, R.C.R., Guterres, S.S. (2016). Polymeric Nanocapsules for Topical Delivery. In: Dragicevic, N., Maibach, H. (eds) Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47862-2_13

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  • DOI: https://doi.org/10.1007/978-3-662-47862-2_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-47861-5

  • Online ISBN: 978-3-662-47862-2

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