Zusammenfassung
Die präfrontale kortikale Dysfunktion der Depression wird beschrieben. Im Zentrum steht die Dysfunktionalität der limbisch-kortikalen Netzwerke (u. a. erhöhte Ruhezustandsaktivität in den Mittellinienregionen des Gehirns). Die unterschiedlichen Formen des neuronalen Processing im präfrontalen Kortex werden als räumlich-zeitliche Muster neuronaler Aktivität charakterisiert. Es werden unterschiedliche psychotherapeutische Interventionen vorgeschlagen, die zu einer Restoration dysfunktionaler Aktivierungsmuster beitragen können
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Northoff, G., Böker, H. (2016). Neuronale Substrate der Depression und Implikationen für die Psychotherapie. In: Böker, H., Hartwich, P., Northoff, G. (eds) Neuropsychodynamische Psychiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47765-6_26
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