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Osteoonkologie: Knochenmetastasen und Tumortherapie-induzierte Osteoporose

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Kompendium Internistische Onkologie

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Zusammenfassung

Die Osteoonkologie untersucht die Wechselwirkung zwischen Tumorerkrankungen, Tumortherapie und dem Knochen und beschäftigt sich mit therapeutischen Möglichkeiten, metabolische und metastatische Skeletterkrankungen zu vermeiden oder zu behandeln. Die Osteoonkologie hat 3 Schwerpunkte: Behandlung von Knochenmetastasen und Knochenschmerzen, Prävention und Behandlung der Tumortherapie-induzierten Osteoporose und Prävention von ossären Metastasen. Die Tumortherapie-induzierte Osteoporose im Rahmen eines therapiebedingten Hypogonadismus durch endokrine oder zytotoxische Substanzen, ist eine Langzeitkomplikation, die in den letzten Jahren zu vermehrter Aufmerksamkeit geführt hat. Onkologen sollten sich mit den Grundlagen der Knochengesundheit auskennen und therapeutische Empfehlungen umsetzen. Daher sollten diejenigen, die für diese Langzeitkomplikation verantwortlich sind, sich weiterbilden, um entscheiden zu können, wann osteoprotektive Medikamente zur Vermeidung einer Fraktur eingesetzt werden sollten und welche Basismaßnahmen zum Erhalt der Knochengesundheit vermittelt werden müssen.

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Correspondence to Ingo J. Diel .

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Diel, I.J., Jehn, CF., Rachner, T.D. (2022). Osteoonkologie: Knochenmetastasen und Tumortherapie-induzierte Osteoporose. In: Schmoll, HJ. (eds) Kompendium Internistische Onkologie . Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46764-0_195-1

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