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Peyronie’s Disease (Induratio Penis Plastica)

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Clinical Uro-Andrology

Abstract

Peyronie’s disease (PD), induratio plastica of the penis, has been a topic of debate with its complex pathologic pathways and ever developing treatment modalities since its initial report by François Gigot de la Peyronie in 1743. PD is an acquired fibrotic disease of the tunica albuginea (TA) of the penis characterized by the formation of fibrous plaques, which cause penile curvature and shortening, painful erection, loss of penile flexibility, and associated sexual dysfunction (Ralph et al. 2010). The incidence of PD is reported as 3.2 % in the Cologne Male Survey of 8,000 men (Schwarzer et al. 2001). Other epidemiological studies estimate the prevalence of PD to be 3–8.9 % with mean age of onset being 50–60 years (Smith et al. 2008; Mulhall et al. 2004). In addition, some studies reported up to 10.8 % prevalence of PD in men younger than the age of 40 who display a more acute onset and lower incidence of ED in comparison with PD encountered in older ages (Levine et al. 2003; Deveci et al. 2007; Kadioglu et al. 2007). PD is also encountered in a special subgroup, teenager population, with diversified qualities such as high HbA1c levels in 18 % of patients, noncontiguous plaques, and subsequent ED rate of 37 %, and they present earlier than their adult counterparts (Tal et al. 2012).

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Authors and Affiliations

  1. Section of Andrology, Department of Urology, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, 34390, Turkey

    Ates Kadioglu MD, Emre Salabas MD & Faruk Küçükdurmaz MD

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  1. Ates Kadioglu MD
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  2. Emre Salabas MD
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  3. Faruk Küçükdurmaz MD
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Correspondence to Ates Kadioglu MD .

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  1. Urology, University of Naples AOU Federico II, Naples, Italy

    Vincenzo Mirone

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Kadioglu, A., Salabas, E., Küçükdurmaz, F. (2015). Peyronie’s Disease (Induratio Penis Plastica). In: Mirone, V. (eds) Clinical Uro-Andrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45018-5_4

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  • DOI: https://doi.org/10.1007/978-3-662-45018-5_4

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