Skip to main content

Influence of Small Bowel Capsule Endoscopy on Clinical Outcome

  • Chapter
  • First Online:
Video Capsule Endoscopy

Abstract

Video capsule endoscopy (VCE) has become the first choice in the evaluation of suspected small bowel bleeding [1–4]. The positive impact of VCE on clinical outcomes in patients with obscure gastrointestinal bleeding (OGIB) has been demonstrated in several studies [5–7]. VCE showed a better diagnostic yield in detecting mucosal lesions in patients with OGIB when compared with radiologic investigations such as small bowel follow-through (SBFT), small bowel enteroclysis (SBE), or cross-sectional imaging such as CT scans or MRI [2, 4, 8–10]. Device-assisted enteroscopy (DAE), which comprises single-balloon, double-balloon, and spiral enteroscopy, also enables inspection of the whole small bowel mucosa and permits the performance of therapeutic interventions [1]. DAE is time-consuming, however; so VCE and DAE should be considered complementary procedures. The effect of VCE on diagnosis and outcome in patients with established Crohn’s disease (CD) and clinically suspected CD has been also demonstrated in several studies [11–15]. Recent studies have also shown that VCE is useful for screening and surveillance of patients with polyposis syndromes [16, 17]. Furthermore, the usefulness of VCE for patients with celiac disease or for patients with symptoms such as chronic diarrhea and chronic abdominal pain (when accompanied by inflammatory markers), and for less frequent small bowel diseases, has been increasingly demonstrated in recent publications [18–22].

The work was first published in 2006 by Springer Medizin Verlag Heidelberg with the following title: Atlas of Video Capsule Endoscopy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Raju GS, Gerson L, Das A, Lewis B. American Gastroenterological Association (AGA) Institute Technical Review on obscure gastrointestinal bleeding. Gastroenterology. 2007;133:1697–717.

    PubMed  Google Scholar 

  2. Triester SL, Leighton JA, Leontiadis GI, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol. 2005;100:2407–18.

    PubMed  Google Scholar 

  3. Koulaouzidis A, Rondonotti E, Giannakou A, Plevris JN. Diagnostic yield of small-bowel capsule endoscopy in patients with iron-deficiency anemia: a systematic review. Gastrointest Endosc. 2012;76:983–92.

    PubMed  Google Scholar 

  4. Milano A, Balatsinou C, Filippone A, et al. A prospective evaluation of iron deficiency anemia in the GI endoscopy setting: role of standard endoscopy, videocapsule endoscopy, and CT-enteroclysis. Gastrointest Endosc. 2011;73:1002–8.

    PubMed  Google Scholar 

  5. Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases. Gastroenterology. 2004;126:643–53.

    PubMed  Google Scholar 

  6. Delvaux M, Fassler I, Gay G. Clinical usefulness of the endoscopic video capsule as the initial intestinal investigation in patients with obscure digestive bleeding: validation of a diagnostic strategy based on the patient outcome after 12 months. Endoscopy. 2004;36:1067–73.

    CAS  PubMed  Google Scholar 

  7. Estevez E, Gonzalez-Conde B, Vazquez-Iglesias JL, et al. Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding. Eur J Gastroenterol Hepatol. 2006;18:881–8.

    PubMed  Google Scholar 

  8. Costamagna G, Shah SK, Riccioni ME, et al. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease. Gastroenterology. 2002;123:999–1005.

    PubMed  Google Scholar 

  9. Huprich JE, Fletcher JG, Fidler JL, et al. Prospective blinded comparison of wireless capsule endoscopy and multiphase CT enterography in obscure gastrointestinal bleeding. Radiology. 2011;260:744–51.

    PubMed  Google Scholar 

  10. Wiarda BM, Heine DGN, Mensink P, et al. Comparison of magnetic resonance enteroclysis and capsule endoscopy with balloon-assisted enteroscopy in patients with obscure gastrointestinal bleeding. Endoscopy. 2012;44:668–73.

    CAS  PubMed  Google Scholar 

  11. Triester SL, Leighton JA, Leontiadis GI, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn’s disease. Am J Gastroenterol. 2006;101:954–64.

    PubMed  Google Scholar 

  12. Eliakim R, Fischer D, Suissa A, et al. Wireless capsule video endoscopy is a superior diagnostic tool in comparison to barium follow-through and computerized tomography in patients with suspected Crohn’s disease. Eur J Gastroenterol Hepatol. 2003;15:363–7.

    PubMed  Google Scholar 

  13. Fireman Z, Mahajna E, Broide E, et al. Diagnosing small bowel Crohn’s disease with wireless capsule endoscopy. Gut. 2003;52:390–2.

    CAS  PubMed Central  PubMed  Google Scholar 

  14. Liangpunsakul S, Chadalawada V, Rex DK, et al. Wireless capsule endoscopy detects small bowel ulcers in patients with normal results from state of the art enteroclysis. Am J Gastroenterol. 2003;98:1295–8.

    PubMed  Google Scholar 

  15. Herrerias JM, Caunedo A, Rodriguez-Tellez M, et al. Capsule endoscopy in patients with suspected Crohn’s disease and negative endoscopy. Endoscopy. 2003;35:564–8.

    CAS  PubMed  Google Scholar 

  16. Caspari R, von Falkenhausen M, Krautmacher C, et al. Comparison of capsule endoscopy and magnetic resonance imaging for the detection of polyps of the small intestine in patients with familial adenomatous polyposis or with Peutz-Jeghers’ syndrome. Endoscopy. 2004;36:1054–9.

    CAS  PubMed  Google Scholar 

  17. Ohmiya N, Nakamura M, Takenaka H, et al. Management of small-bowel polyps in Peutz-Jeghers syndrome by using enteroclysis, double-balloon enteroscopy, and videocapsule endoscopy. Gastrointest Endosc. 2010;72:1209–16.

    PubMed  Google Scholar 

  18. Katsinelos P, Fasoulas K, Beltsis A, et al. Diagnostic yield and clinical impact of wireless capsule endoscopy in patients with chronic abdominal pain with or without diarrhea: a Greek multicenter study. Eur J Intern Med. 2011;22:e63–6.

    PubMed  Google Scholar 

  19. Kurien M, Evans KE, Aziz I, et al. Capsule endoscopy in adult celiac disease: a potential role in equivocal cases of celiac disease? Gastrointest Endosc. 2013;77:227–32.

    PubMed  Google Scholar 

  20. Collin P, Rondonotti E, Lundin KE, et al. Video capsule endoscopy in celiac disease: current clinical practice. J Dig Dis. 2012;13:94–9.

    PubMed  Google Scholar 

  21. Lidums I, Teo E, Field J, Cummins AG. Capsule endoscopy: a valuable tool in the follow-up of people with celiac disease on a gluten-free diet. Clin Transl Gastroenterol. 2011;2:e4.

    PubMed Central  PubMed  Google Scholar 

  22. Oette M, Stelzer A, Göbels K, et al. Wireless capsule endoscopy for the detection of small bowel diseases in HIV-1-infected patients. Eur J Med Res. 2009;14:191–4.

    PubMed Central  PubMed  Google Scholar 

  23. Chami G, Raza M, Bernstein CN. Usefulness and impact on management of positive and negative capsule endoscopy. Can J Gastroenterol. 2007;21:577–81.

    PubMed Central  PubMed  Google Scholar 

  24. Barkin JS, O’Loughlin C. Capsule endoscopy contraindications: complications and how to avoid their occurrence. Gastrointest Endosc Clin N Am. 2004;14:61–5.

    PubMed  Google Scholar 

  25. Höög CM, Bark LÅ, Arkani J, et al. Capsule retentions and incomplete capsule endoscopy examinations: an analysis of 2300 examinations. Gastroenterol Res Pract. 2012;2012:518718.

    PubMed Central  PubMed  Google Scholar 

  26. Rastogi A, Schoen RE, Slivka A. Diagnostic yield and clinical outcomes of capsule endoscopy. Gastrointest Endosc. 2004;60:959–64.

    PubMed  Google Scholar 

  27. Saurin JC, Delvaux M, Gaudin JL, et al. Diagnostic value of endoscopic capsule in patients with obscure digestive bleeding: blinded comparison with video push-enteroscopy. Endoscopy. 2003;35:576–84.

    PubMed  Google Scholar 

  28. Neu B, Ell C, May A, et al. Capsule endoscopy versus standard tests in influencing management of obscure digestive bleeding: results from a German multicenter trial. Am J Gastroenterol. 2005;100:1736–42.

    PubMed  Google Scholar 

  29. Lewis BS. Small intestinal bleeding. Gastroenterol Clin North Am. 1994;23:67–91.

    CAS  PubMed  Google Scholar 

  30. Lewis BS, Swain P. Capsule endoscopy in the evaluation of patients with suspected small intestinal bleeding: results of a pilot study. Gastrointest Endosc. 2002;56:349–53.

    PubMed  Google Scholar 

  31. Ell C, Remke S, May A, et al. The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding. Endoscopy. 2002;34:685–9.

    CAS  PubMed  Google Scholar 

  32. Mata A, Bordas JM, Feu F, et al. Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy. Aliment Pharmacol Ther. 2004;20:189–94.

    CAS  PubMed  Google Scholar 

  33. Hartmann D, Schmidt H, Schilling D, et al. Follow-up of patients with obscure gastrointestinal bleeding after capsule endoscopy and intraoperative enteroscopy. Hepatogastroenterology. 2007;54:780–3.

    PubMed  Google Scholar 

  34. Zhang B, Jiang L, Chen C, et al. Diagnosis of obscure gastrointestinal hemorrhage with capsule endoscopy in combination with multiple-detector computed tomography. J Gastroenterol Hepatol. 2010;25:75–9.

    PubMed  Google Scholar 

  35. Khalife S, Soyer P, Alatawi A, et al. Obscure gastrointestinal bleeding: preliminary comparison of 64-section CT enteroclysis with video capsule endoscopy. Eur Radiol. 2011;21:79–86.

    PubMed  Google Scholar 

  36. Saperas E, Dot J, Videla S, et al. Capsule endoscopy versus computed tomographic or standard angiography for the diagnosis of obscure gastrointestinal bleeding. Am J Gastroenterol. 2007;102:731–7.

    PubMed  Google Scholar 

  37. Voderholzer WA, Ortner M, Rogalla P, et al. Diagnostic yield of wireless capsule enteroscopy in comparison with computed tomography enteroclysis. Endoscopy. 2003;35:1009–14.

    CAS  PubMed  Google Scholar 

  38. Heo HM, Park CH, Lim JS, et al. The role of capsule endoscopy after negative CT enterography in patients with obscure gastrointestinal bleeding. Eur Radiol. 2012;22:1159–66.

    PubMed  Google Scholar 

  39. Apostolopoulos P, Liatsos C, Gralnek IM, et al. The role of wireless capsule endoscopy in investigating unexplained iron deficiency anemia after negative endoscopic evaluation of the upper and lower gastrointestinal tract. Endoscopy. 2006;38:1127–32.

    CAS  PubMed  Google Scholar 

  40. Riccioni ME, Urgesi R, Spada C, et al. Unexplained iron deficiency anaemia: is it worthwhile to perform capsule endoscopy? Dig Liver Dis. 2010;42:560–6.

    PubMed  Google Scholar 

  41. Holleran GE, Barry SA, Thornton OJ, et al. The use of small bowel capsule endoscopy in iron deficiency anaemia: low impact on outcome in the medium term despite high diagnostic yield. Eur J Gastroenterol Hepatol. 2013;25:327–32.

    PubMed  Google Scholar 

  42. Tang SJ, Christodoulou D, Zanati S, et al. Wireless capsule endoscopy for obscure gastrointestinal bleeding: a single-centre, one-year experience. Can J Gastroenterol. 2004;18:559–65.

    PubMed  Google Scholar 

  43. Fry LC, Bellutti M, Neumann H, et al. Incidence of bleeding lesions within reach of conventional upper and lower endoscopes in patients undergoing double-balloon enteroscopy for obscure gastrointestinal bleeding. Aliment Pharmacol Ther. 2009;29:342–9.

    CAS  PubMed  Google Scholar 

  44. Yamada A, Watabe H, Kobayashi Y, et al. Timing of capsule endoscopy influences the diagnosis and outcome in obscure-overt gastrointestinal bleeding. Hepatogastroenterology. 2012;59:676–9.

    PubMed  Google Scholar 

  45. Marmo R, Rotondano G, Casetti T, et al. Degree of concordance between double-balloon enteroscopy and capsule endoscopy in obscure gastrointestinal bleeding: a multicenter study. Endoscopy. 2009;41:587–92.

    CAS  PubMed  Google Scholar 

  46. Shishido T, Oka S, Tanaka S, et al. Diagnostic yield of capsule endoscopy vs double-balloon endoscopy for patients who have undergone total enteroscopy with obscure gastrointestinal bleeding. Hepatogastroenterology. 2012;59:955–9.

    PubMed  Google Scholar 

  47. Teshima CW, Kuipers EJ, van Zanten SV, Mensink PBF. Double balloon enteroscopy and capsule endoscopy for obscure gastrointestinal bleeding: an updated meta-analysis. J Gastroenterol Hepatol. 2011;26:796–801.

    PubMed  Google Scholar 

  48. Honda W, Ohmiya N, Hirooka Y, et al. Enteroscopic and radiologic diagnoses, treatment, and prognoses of small-bowel tumors. Gastrointest Endosc. 2012;76:344–54.

    PubMed  Google Scholar 

  49. Mönkemüller K, Neumann H, Meyer F, et al. A retrospective analysis of emergency double-balloon enteroscopy for small-bowel bleeding. Endoscopy. 2009;41:715–7.

    PubMed  Google Scholar 

  50. Fujimori S, Seo T, Gudis K, et al. Diagnosis and treatment of obscure gastrointestinal bleeding using combined capsule endoscopy and double balloon endoscopy: 1-year follow-up study. Endoscopy. 2007;39:1053–8.

    CAS  PubMed  Google Scholar 

  51. Albert JG, Schulbe R, Hahn L, et al. Impact of capsule endoscopy on outcome in mid-intestinal bleeding: a multicentre cohort study in 285 patients. Eur J Gastroenterol Hepatol. 2008;20:971–7.

    PubMed  Google Scholar 

  52. Hindryckx P, Botelberge T, De Vos M, De Looze D. Clinical impact of capsule endoscopy on further strategy and long-term clinical outcome in patients with obscure bleeding. Gastrointest Endosc. 2008;68:98–104.

    PubMed  Google Scholar 

  53. Apostolopoulos P, Liatsos C, Gralnek IM, et al. Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding. Gastrointest Endosc. 2007;66:1174–81.

    PubMed  Google Scholar 

  54. Iwamoto J, Mizokami Y, Shimokobe K, et al. The clinical outcome of capsule endoscopy in patients with obscure gastrointestinal bleeding. Hepatogastroenterology. 2011;58:301–5.

    PubMed  Google Scholar 

  55. May A, Friesing-Sosnik T, Manner H, et al. Long-term outcome after argon plasma coagulation of small-bowel lesions using double-balloon enteroscopy in patients with mid-gastrointestinal bleeding. Endoscopy. 2011;43:759–65.

    CAS  PubMed  Google Scholar 

  56. Samaha E, Rahmi G, Landi B, et al. Long-term outcome of patients treated with double balloon enteroscopy for small bowel vascular lesions. Am J Gastroenterol. 2012;107:240–6.

    CAS  PubMed  Google Scholar 

  57. Eliakim R, Suissa A, Yassin K, et al. Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn’s disease–final report. Dig Liver Dis. 2004;36:519–22.

    CAS  PubMed  Google Scholar 

  58. Voderholzer WA, Beinhoelzl J, Rogalla P, et al. Small bowel involvement in Crohn’s disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis. Gut. 2005;54:369–73.

    CAS  PubMed Central  PubMed  Google Scholar 

  59. Albert JG, Martiny F, Krummenerl A, et al. Diagnosis of small bowel Crohn’s disease: a prospective comparison of capsule endoscopy with magnetic resonance imaging and fluoroscopic enteroclysis. Gut. 2005;54:1721–7.

    CAS  PubMed Central  PubMed  Google Scholar 

  60. Golder SK, Schreyer AG, Endlicher E, et al. Comparison of capsule endoscopy and magnetic resonance (MR) enteroclysis in suspected small bowel disease. Int J Colorectal Dis. 2006;21:97–104.

    PubMed  Google Scholar 

  61. Hara AK, Leighton JA, Heigh RI, et al. Crohn disease of the small bowel: preliminary comparison among CT enterography, capsule endoscopy, small-bowel follow-through, and ileoscopy. Radiology. 2006;238:128–34.

    PubMed  Google Scholar 

  62. Solem CA, Loftus EVJ, Fletcher JG, et al. Small-bowel imaging in Crohn’s disease: a prospective, blinded, 4-way comparison trial. Gastrointest Endosc. 2008;68:255–66.

    PubMed  Google Scholar 

  63. Tillack C, Seiderer J, Brand S, et al. Correlation of magnetic resonance enteroclysis (MRE) and wireless capsule endoscopy (CE) in the diagnosis of small bowel lesions in Crohn’s disease. Inflamm Bowel Dis. 2008;14:1219–28.

    PubMed  Google Scholar 

  64. Böcker U, Dinter D, Litterer C, et al. Comparison of magnetic resonance imaging and video capsule enteroscopy in diagnosing small-bowel pathology: localization-dependent diagnostic yield. Scand J Gastroenterol. 2010;45:490–500.

    PubMed  Google Scholar 

  65. Jensen MD, Nathan T, Rafaelsen SR, Kjeldsen J. Diagnostic accuracy of capsule endoscopy for small bowel Crohn’s disease is superior to that of MR enterography or CT enterography. Clin Gastroenterol Hepatol. 2011;9:124–9.

    PubMed  Google Scholar 

  66. Casciani E, Masselli G, Di Nardo G, et al. MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn’s disease. Eur Radiol. 2011;21:823–31.

    PubMed  Google Scholar 

  67. Dionisio PM, Gurudu SR, Leighton JA, et al. Capsule endoscopy has a significantly higher diagnostic yield in patients with suspected and established small-bowel Crohn’s disease: a meta-analysis. Am J Gastroenterol. 2010;105:1240–8.

    PubMed  Google Scholar 

  68. Adler SN, Yoav M, Eitan S, et al. Does capsule endoscopy have an added value in patients with perianal disease and a negative work up for Crohn’s disease? World J Gastrointest Endosc. 2012;4:185–8.

    PubMed Central  PubMed  Google Scholar 

  69. Mow WS, Lo SK, Targan SR, et al. Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease. Clin Gastroenterol Hepatol. 2004;2:31–40.

    PubMed  Google Scholar 

  70. Chong AK, Taylor A, Miller A, et al. Capsule endoscopy vs push enteroscopy and enteroclysis in suspected small-bowel Crohn’s disease. Gastrointest Endosc. 2005;61:255–61.

    PubMed  Google Scholar 

  71. Dussault C, Gower-Rousseau C, Salleron J, et al. Small bowel capsule endoscopy for management of Crohn’s disease: a retrospective tertiary care centre experience. Dig Liver Dis. 2013;45:558–61.

    PubMed  Google Scholar 

  72. Albert JG, Kotsch J, Köstler W, et al. Course of Crohn’s disease prior to establishment of the diagnosis. Z Gastroenterol. 2008;46:187–92.

    CAS  PubMed  Google Scholar 

  73. Tukey M, Pleskow D, Legnani P, et al. The utility of capsule endoscopy in patients with suspected Crohn’s disease. Am J Gastroenterol. 2009;104:2734–9.

    PubMed  Google Scholar 

  74. Maunoury V, Savoye G, Bourreille A, et al. Value of wireless capsule endoscopy in patients with indeterminate colitis (inflammatory bowel disease type unclassified). Inflamm Bowel Dis. 2007;13:152–5.

    PubMed  Google Scholar 

  75. Liao Z, Gao R, Xu C, Li Z. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review. Gastrointest Endosc. 2010;71:280–6.

    PubMed  Google Scholar 

  76. Burri E, Beglinger C. Faecal calprotectin – a useful tool in the management of inflammatory bowel disease. Swiss Med Wkly. 2012;142:w13557.

    PubMed  Google Scholar 

  77. Koulaouzidis A, Douglas S, Rogers MA, et al. Fecal calprotectin: a selection tool for small bowel capsule endoscopy in suspected IBD with prior negative bi-directional endoscopy. Scand J Gastroenterol. 2011;46:561–6.

    CAS  PubMed  Google Scholar 

  78. Sipponen T, Haapamaki J, Savilahti E, et al. Fecal calprotectin and S100A12 have low utility in prediction of small bowel Crohn’s disease detected by wireless capsule endoscopy. Scand J Gastroenterol. 2012;47:778–84.

    CAS  PubMed  Google Scholar 

  79. Keuchel M, Hagenmüller F. Video capsule endoscopy in the work-up of abdominal pain. Gastrointest Endosc Clin N Am. 2004;14:195–205.

    PubMed  Google Scholar 

  80. Bardan E, Nadler M, Chowers Y, et al. Capsule endoscopy for the evaluation of patients with chronic abdominal pain. Endoscopy. 2003;35:688–9.

    CAS  PubMed  Google Scholar 

  81. Fry LC, Carey EJ, Shiff AD, et al. The yield of capsule endoscopy in patients with abdominal pain or diarrhea. Endoscopy. 2006;38:498–502.

    CAS  PubMed  Google Scholar 

  82. De Bona M, Bellumat A, Cian E, et al. Capsule endoscopy findings in patients with suspected Crohn’s disease and biochemical markers of inflammation. Dig Liver Dis. 2006;38:331–5.

    PubMed  Google Scholar 

  83. Valle J, Alcántara M, Pérez-Grueso MJ, et al. Clinical features of patients with negative results from traditional diagnostic work-up and Crohn’s disease findings from capsule endoscopy. J Clin Gastroenterol. 2006;40:692–6.

    PubMed  Google Scholar 

  84. Fidder HH, Nadler M, Lahat A, et al. The utility of capsule endoscopy in the diagnosis of Crohn’s disease based on patient’s symptoms. J Clin Gastroenterol. 2007;41:384–7.

    PubMed  Google Scholar 

  85. Shim KN, Kim YS, Kim KJ, et al. Abdominal pain accompanied by weight loss may increase the diagnostic yield of capsule endoscopy: a Korean multicenter study. Scand J Gastroenterol. 2006;41:983–8.

    PubMed  Google Scholar 

  86. May A, Manner H, Schneider M, et al. Prospective multicenter trial of capsule endoscopy in patients with chronic abdominal pain, diarrhea and other signs and symptoms (CEDAP-Plus Study). Endoscopy. 2007;39:606–12.

    CAS  PubMed  Google Scholar 

  87. Mele C, Infantolino A, Conn M, et al. The diagnostic yield of wireless capsule endoscope in patients with unexplained abdominal pain. Am J Gastroenterol. 2003;98:S298.

    Google Scholar 

  88. Nakamura M, Ohmiya N, Miyahara R, et al. Are symptomatic changes in irritable bowel syndrome correlated with the capsule endoscopy transit time? A pilot study using the 5-HT4 receptor agonist mosapride. Hepatogastroenterology. 2011;58:453–8.

    PubMed  Google Scholar 

  89. Hooks 3rd SB, Rutland TJ, Di Palma JA. Lubiprostone neither decreases gastric and small-bowel transit time nor improves visualization of small bowel for capsule endoscopy: a double-blind, placebo-controlled study. Gastrointest Endosc. 2009;70:942–6.

    PubMed  Google Scholar 

  90. Soares J, Lopes L, Vilas Boas G, Pinho C. Wireless capsule endoscopy for evaluation of phenotypic expression of small-bowel polyps in patients with Peutz-Jeghers’ syndrome and in symptomatic first-degree relatives. Endoscopy. 2004;36:1060–6.

    CAS  PubMed  Google Scholar 

  91. Spada C, Riccioni ME, Familiari P, et al. Video capsule endoscopy in small-bowel tumours: a single centre experience. Scand J Gastroenterol. 2008;43:497–505.

    PubMed  Google Scholar 

  92. Cheung DY, Lee IS, Chang DK, et al. Capsule endoscopy in small bowel tumors: a multicenter Korean study. J Gastroenterol Hepatol. 2010;25:1079–86.

    PubMed  Google Scholar 

  93. Urgesi R, Riccioni ME, Bizzotto A, et al. Increased diagnostic yield of small bowel tumors with PillCam: the role of capsule endoscopy in the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). Italian single-center experience. Tumori. 2012;98:357–63.

    PubMed  Google Scholar 

  94. Albert JG, Fiedler E, Marsch WC, Helmbold P. Consequences of detecting small bowel metastasis of malignant melanoma by capsule endoscopy. Am J Gastroenterol. 2008;103:244–5.

    PubMed  Google Scholar 

  95. Katsinelos P, Fasoylas K, Chatzimavroudis G, et al. Diagnostic yield and clinical management after capsule endoscopy in daily clinical practice: a single-center experience. Hippokratia. 2010;14:271–6.

    CAS  PubMed Central  PubMed  Google Scholar 

  96. Murray JA, Rubio-Tapia A, Van Dyke CT, et al. Mucosal atrophy in celiac disease: extent of involvement, correlation with clinical presentation, and response to treatment. Clin Gastroenterol Hepatol. 2008;6:186–93.

    PubMed Central  PubMed  Google Scholar 

  97. Mizukami K, Murakami K, Yamauchi M, et al. Evaluation of selective cyclooxygenase-2 inhibitor-induced small bowel injury: randomized cross-over study compared with loxoprofen in healthy subjects. Dig Endosc. 2013;25:288–94.

    PubMed  Google Scholar 

  98. Watanabe T, Tanigawa T, Nadatani Y, et al. Risk factors for severe nonsteroidal anti-inflammatory drug-induced small intestinal damage. Dig Liver Dis. 2013;45:390–5.

    CAS  PubMed  Google Scholar 

  99. Karagiannis S, Faiss S, Mavrogiannis C. Capsule retention: a feared complication of wireless capsule endoscopy. Scand J Gastroenterol. 2009;44:1158–65.

    PubMed  Google Scholar 

  100. Lee BI, Choi H, Choi KY, et al. Retrieval of a retained capsule endoscope by double-balloon enteroscopy. Gastrointest Endosc. 2005;62:463–5.

    PubMed  Google Scholar 

  101. Cheifetz AS, Lewis BS. Capsule endoscopy retention: is it a complication? J Clin Gastroenterol. 2006;40:688–91.

    PubMed  Google Scholar 

  102. Figueiredo P, Almeida N, Lopes S, et al. Small-bowel capsule endoscopy in patients with suspected Crohn’s disease—diagnostic value and complications. Diagn Ther Endosc. 2010;2010:pii: 101284.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lucia C. Fry .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Fry, L.C., Hagenmüller, F., Albert, J.G., Fleischer, D.E. (2014). Influence of Small Bowel Capsule Endoscopy on Clinical Outcome. In: Keuchel, M., Hagenmüller, F., Tajiri, H. (eds) Video Capsule Endoscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44062-9_41

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-44062-9_41

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44061-2

  • Online ISBN: 978-3-662-44062-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics