Zusammenfassung
Über eine Milliarde Menschen in Entwicklungsländern leiden an Infektionskrankheiten, die nicht behandelbar sind oder eine Resistenz gegen verfügbare Medikamente zeigen. Aus diesem Grunde sind neuartige Konzepte zur Behandlung von diesen häufig vernachlässigten Infektionskrankheiten erforderlich. Das Einbringen von know‐how und Erfahrungen aus der Herbizidentwicklung könnte ein neuer Weg sein für die entwicklung neuartiger Antibiotika gegen diese Krankheiten. Erste vielversprechende Erfolge konnten mit diesem Ansatz auf dem Gebiet der Malaria und der Chagas‐Krankheit erzielt werden.
Abstract
Over one billion people in developing countries suffer from infectious diseases that are not curable or that show widespread resistance to current medication. Therefore new concepts besides the traditional optimization approaches for the identification of potential new drugs against these neglected diseases are badly needed. The utilization of crop protection knowhow for the identification could become an important avenue for the discovery of new drugs against these diseases. Despite the seemingly unrelated topics, very promising results especially against malaria and Chagas disease could be achieved using this approach.
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Witschel, M. (2014). Neue Wirkstoffe gegen Malaria und vernachlässigte Krankheiten aus der Pflanzenschutzforschung. In: Fischer, M. (eds) Neue und alte Infektionskrankheiten. Springer Spektrum, Wiesbaden. https://doi.org/10.1007/978-3-658-04124-3_6
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DOI: https://doi.org/10.1007/978-3-658-04124-3_6
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