Abstract
Hepatocellular carcinoma (HCC or hepatoma) is one of the most common malignancies. Worldwide, the annual incidence is nearly 1 million and it causes an estimated 1,250,000 deaths every year. There is striking geographic variation, the highest rates being found in China, Southeast Asia, and sub-Saharan Africa (>20, and up to 100/100,000 males per year). The lowest rates (<5/100,000 males per year) are found in Northern Europe, North America, and Latin America [1].
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Mani, S., Johnson, P.J. (2003). Hepatobiliary Cancer, Pancreatic Cancer, and Neuroendocrine Cancers of the Gastrointestinal Tract. In: Vokes, E.E., Golomb, H.M. (eds) Oncologic Therapies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55780-4_34
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