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Chronische Pankreatitis: Ätiologie, Pathogenese und Genetik

DGIM Innere Medizin

Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

Bei der chronischen Pankreatitis handelt sich um eine chronisch-entzündliche Erkrankung des Pankreas mit akut entzündlichen Schüben oder primär chronischem Verlauf mit allmählicher Zerstörung des exokrinen und endokrinen Gewebes und Ersatz durch Bindegewebe. Zu den Risikofaktoren zählen langjähriger Alkoholkonsum, Rauchen, genetische Faktoren und eventuell in sehr selten Fällen auch die Entwicklungsanomalie eines Pankreas divisum. Alle Gene, die mit der chronischen Pankreatitis assoziiert sind, scheinen die Verdauungsenzymkaskade mit ihrer zentralen Protease Trypsin zu beeinflussen.

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Author information

Authors and Affiliations

  1. Medizinische Klinik und Poliklinik für Gastroenterologie und Rheumatologie, Universitätsklinikum Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland

    Joachim Mössner

  2. Universitätsklinik und Poliklinik für Innere Medizin I, Universitätsklinikum Halle, Ernst-Grube-Straße 40, 06120, Halle (Saale), Deutschland

    Jonas Rosendahl

Authors
  1. Joachim Mössner
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  2. Jonas Rosendahl
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Corresponding author

Correspondence to Joachim Mössner .

Editor information

Editors and Affiliations

  1. Medizinische Klinik I, Universitätsklinikum Schleswig-Hoslstein, Campus Lübeck, Lübeck, Schleswig-Holstein, Germany

    Hendrik Lehnert

  2. TU Dresden Universitätsklinikum Carl Gustav Carus, Dresden, Germany

    Sebastian M. Schellong

  3. FB Gastroenterologie und Hepatologie, Universitätsklinikum Leipzig Medizinische Klinik und Poliklinik II, Leipzig, Sachsen, Germany

    Joachim Mössner

  4. Krankenhaus Barmherzige Brüder, Regensburg, Germany

    Cornel C. Sieber

  5. Nürnberg, Bayern, Germany

    Walter Swoboda

  6. Universitätsklinikum Giessen und Marburg Klinik für Innere Medizin, Marburg, Hessen, Germany

    Andreas Neubauer

  7. Interdisziplinärer Schwerpunkt für Hämos, Universitätsklinikum Gießen und Marburg, Gießen, Germany

    Bettina Kemkes-Matthes

  8. Klinik für Gastroenterologie,Hepatologie, Medizinische Hochschule Hannover, Hannover, Germany

    Michael P. Manns

  9. Sektion für Molekulare und Klinische Inf, Universitätsklinikum Schleswig-Holstein,, Lübeck, Germany

    Jan Rupp

  10. Abt. Kardiologie und Pneumologie, Universitätsklinikum Göttingen Herzzentrum Göttingen, Göttingen, Germany

    Gerd Hasenfuß

  11. Abt. Nephrologie und Klinische Immunologie, Univ.Klinikum Aachen Medizinische Klinik II, Aachen, Germany

    J. Floege

  12. Universitätsklinikum Köln Klinik I für Innere Medizin, Köln, Germany

    Michael Hallek

  13. Klinik für Pneumologie, Medizinische Hochschule Hannover (MHH) Zentrum Innere Medizin, Hannover, Germany

    Tobias Welte

  14. Klinik u. Poliklinik für Innere Medizin, Universitätsmedizin Greifswald, Greifswald, Germany

    Markus Lerch

  15. Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Germany

    Elisabeth Märker-Hermann

  16. Klinische Toxikologie, Giftinformation, Universitätsklinikum Mainz II. Medizinische Klinik und Poliklinik, Mainz, Germany

    Ludwig Sacha Weilemann

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Mössner, J., Rosendahl, J. (2015). Chronische Pankreatitis: Ätiologie, Pathogenese und Genetik. In: Lehnert, H., et al. DGIM Innere Medizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54676-1_114-1

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  • DOI: https://doi.org/10.1007/978-3-642-54676-1_114-1

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  • Online ISBN: 978-3-642-54676-1

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Chapter history

  1. Latest

    Chronische Pankreatitis: Ätiologie, Pathogenese und Genetik
    Published:
    05 February 2024

    DOI: https://doi.org/10.1007/978-3-642-54676-1_114-2

  2. Original

    Chronische Pankreatitis: Ätiologie, Pathogenese und Genetik
    Published:
    28 August 2015

    DOI: https://doi.org/10.1007/978-3-642-54676-1_114-1

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