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Arthrose des Kniegelenkes – Konservative Therapie

Nichtpharmakologische Maßnahmen, pharmakologische Therapie, Ernährung/Nahrungsergänzung

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Orthopädie und Unfallchirurgie

Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

Die Arthrose ist eine chronisch progrediente Erkrankung. Während in der Vergangenheit die konservative Behandlung oft nur als Interimstherapie bis zum endoprothetischen Gelenkersatz gesehen wurde, treten heute langfristige individuelle und multimodale Therapieansätze in den Vordergrund. Hierbei umfasst die Basistherapie Gewichtskontrolle, Patientenschulung und Mobilisation. Ergänzend kommen physikalische Therapie und orthopädische Hilfsmittel zum Einsatz. Die pharmakologische Therapie zielt auf Schmerzreduktion und Funktionsverbesserung mit systemischen und lokalen Behandlungsoptionen. Vorrangig kommen nichtsteroidale Antiphlogistika zur kurzzeitigen Anwendung. Intraartikuläre Injektionen ergänzen den symptomatischen Therapieansatz. Da bis dato keine Medikamente zugelassen sind, die eine Degeneration des Gelenkknorpels verhindern bzw. diesen regenerieren können, wecken neue Therapieverfahren wie plättchenreiches Plasma, autologe Stammzellen oder monoklonale Antikörper große Erwartungen. Vor dem Hintergrund ihrer teilweise nicht ausreichend belegten Wirksamkeit sind diese Verfahren jedoch weiterhin zurückhaltend zu bewerten.

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Authors and Affiliations

  1. Klinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes, Homburg/Saar, Deutschland

    Ulrich Grün & Henning Madry

  2. Institut für Experimentelle Orthopädie und Arthroseforschung, Lehrstuhl für Experimentelle Orthopädie und Arthroseforschung, Universität des Saarlandes, Homburg/Saar, Deutschland

    Henning Madry

Authors
  1. Ulrich Grün
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  2. Henning Madry
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Correspondence to Henning Madry .

Editor information

Editors and Affiliations

  1. Klinik für Orthopädie, Klinikum Osnabrück GmbH Klinik für Orthopädie, Osnabrück, Niedersachsen, Deutschland

    Martin Engelhardt

  2. Unfallchirurgie, Universitätsklinikum Münster Unfallchirurgie, Münster, Nordrhein-Westfalen, Deutschland

    Michael Raschke

Section Editor information

  1. Orthopädie, Unfall- und Handchirurgie, Klinikum Osnabrück, Osnabrück, Deutschland

    Martin Engelhardt

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© 2023 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

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Grün, U., Madry, H. (2023). Arthrose des Kniegelenkes – Konservative Therapie. In: Engelhardt, M., Raschke, M. (eds) Orthopädie und Unfallchirurgie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54673-0_310-1

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  • DOI: https://doi.org/10.1007/978-3-642-54673-0_310-1

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  • Print ISBN: 978-3-642-54673-0

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