Abstract
Infections are the second most common cause of morbidity and mortality in chronic kidney disease patients. Uraemia-induced immune dysfunction, frequent visits to health-care facilities, hospitalisation for non-infectious complications, need of vascular catheters and extracorporeal treatment increase infection risk. Urinary tract infections, pneumonia and sepsis are common in pre-dialysis patients, whereas access-related infections, pneumonia, sepsis and blood-borne infections are common in dialysis population. Despite a decrease in rate of blood-borne infections due to improved barrier techniques, the overall rate of infections remains high. Infections also increase the risk of adverse cardiovascular events. Timely creation of vascular access, vaccination and implementation of infection control guidelines are important for infection prevention. Chronic kidney disease patients need to be vaccinated against hepatitis B virus, pneumococcus and influenza. Vaccination response may be suboptimal and needs monitoring. Preventing superimposed acute kidney injury and drug toxicity is important consideration while managing infections in these patients.
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Kumar, V., Jha, V. (2014). Infectious Complications and Vaccination in Chronic Kidney Disease. In: Arici, M. (eds) Management of Chronic Kidney Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54637-2_18
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DOI: https://doi.org/10.1007/978-3-642-54637-2_18
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