Skip to main content
SpringerLink
Log in

Radio-frequency Ablation and Cryoablation for Renal Cell Carcinoma

  • Chapter
  • First Online:
Radiological Imaging of the Kidney

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 3022 Accesses

Abstract

Percutaneous tumor ablation has become one of the most prevalent treatment options for small renal cell carcinomas given continued favorable outcome and is already a treatment of choice for selected patients. Currently, the most common indications are elderly patients with small incidental tumors of unclear metastatic potential and high-risk surgical patients since this procedure has been shown to be safe in patients with multiple comorbidities. This chapter describes the indications, applicators, procedure, outcomes, and complications of percutaneous tumor ablation of renal cell carcinoma. Importantly, the technologies are continuously improving, and it is expected that patient selection and satisfaction will continue to expand and outcomes will continue to improve.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Ahmed M, Liu Z, Afzal KS et al (2004) Radiofrequency ablation: effect of surrounding tissue composition on coagulation necrosis in a canine tumor model. Radiology 230(3):761–767

    Article  PubMed  Google Scholar 

  • Ahmed M, Liu Z, Humphries S et al (2008) Computer modeling of the combined effects of perfusion, electrical conductivity, and thermal conductivity on tissue heating patterns in radiofrequency tumor ablation. Int J Hyperthermia 24(7):577–588

    Article  PubMed  Google Scholar 

  • Ahrar K, Matin S, Wood CG et al (2005) Percutaneous radiofrequency ablation of renal tumors: technique, complications, and outcomes. J Vasc Interv Radiol 16:679–688

    Article  PubMed  Google Scholar 

  • Atwell TD, Farrell MA, Callstrom MR et al (2007) Percutaneous cryoablation of large renal masses: technical feasibility and short-term outcome. AJR Am J Roentgenol 188(5):1195–1200

    Article  PubMed  Google Scholar 

  • Atwell TD, Farrell MA, Leibovich BC et al (2008) Percutaneous renal cryoablation: experience treating 115 tumors. J Urol 179(6):2136–2140

    Article  PubMed  Google Scholar 

  • Atwell TD, Schmit GD, Boorjian SA et al (2013) Percutaneous ablation of renal masses measuring 3.0cm and smaller: comparative local control and complications after radiofrequency ablation and cryoablation. AJR Am J Roentgenol 200(2):461–466

    Article  PubMed  Google Scholar 

  • Beland MD, Mayo-Smith WW, Dupuy DE et al (2007) Diagnostic yield of 58 consecutive imaging-guided biopsies of solid renal masses: should we biopsy all that are indeterminate? AJR Am J Roentgenol 188(3):792–797

    Article  PubMed  Google Scholar 

  • Brace CL, Laeseke PF, Sampson LA et al (2007) Microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: results from an in vivo swine liver model. Radiology 244(1):151–156

    Article  PubMed  Google Scholar 

  • Bush WH Jr, Burnett LL, Gibbons RP (1977) Needle tract seeding of renal cell carcinoma. AJR Am J Roentgenol 129(4):725–727

    Article  PubMed  Google Scholar 

  • Carrafiello G, Laganà D, Mangini M et al (2008) Microwave tumors ablation: principles, clinical applications and review of preliminary experiences. Int J Surg 6(Suppl 1):S65–S69

    Article  PubMed  Google Scholar 

  • Castillo OA, Vitagliano G (2008) Port site metastasis and tumor seeding in oncologic laparoscopic urology. Urology 71(3):373–378

    Article  Google Scholar 

  • Chow WH, Devesa SS, Warren JL et al (1999) Rising incidence of renal cell cancer in the United States. JAMA 281:1628–1631

    Article  PubMed  CAS  Google Scholar 

  • Clark PE, Woodruff RD, Zagoria RJ et al (2007) Microwave ablation of renal parenchymal tumors before nephrectomy: phase I study. AJR Am J Roentgenol 188(5):1212–1214

    Article  PubMed  Google Scholar 

  • Cohen HT, McGovern FJ (2005) Renal-cell carcinoma. N Engl J Med 353:2477–2490

    Article  PubMed  CAS  Google Scholar 

  • Dupuy DE, Safran H, Mayo-Smith WW et al (1998) Radiofrequency ablation of painful osseous metastases. Radiology 209(P):389

    Google Scholar 

  • Dupuy DE et al (2006) Radiofrequency ablation followed by conventional radiotherapy for medically inoperable stage I non-small cell lung cancer. Chest 129(3):738–745

    Article  PubMed  Google Scholar 

  • Edmunds TB, Schulsinger DA, Durand DB et al (2000) Acute histologic changes in human renal tumors after cryoablation. J Endourol 14(2):139–143

    Article  PubMed  Google Scholar 

  • Finley DS, Beck S, Box G et al (2008) Percutaneous and laparoscopic cryoablation of small renal masses. J Urol 180(2):492–498

    Article  PubMed  Google Scholar 

  • Ganguli S, Brennan DD, Faintuch S et al (2008) Immediate renal tumor involution after radiofrequency thermal ablation. J Vasc Interv Radiol 19(3):412–418

    Article  PubMed  Google Scholar 

  • Geoffrey EW, Leyendecker JR, Krehbiel KA et al (2007) CT and MR imaging after imaging-guided thermal ablation of renal neoplasms. Radiographics 27:325–339

    Article  Google Scholar 

  • Gervais DA, McGovern FJ, Arellano RS et al (2003) Renal cell carcinoma: clinical experience and technical success with radio-frequency ablation of 42 tumors. Radiology 226:417–424

    Article  PubMed  Google Scholar 

  • Gervais DA, Arellano RS, McGovern FJ et al (2005a) Radiofrequency ablation of renal cell carcinoma. II. Lessons learned with ablation of 100 tumors. AJR Am J Roentgenol 185:72–80

    Article  PubMed  Google Scholar 

  • Gervais DA, McGovern FJ, Arellano RS et al (2005b) Radiofrequency ablation of renal cell carcinoma. I. Indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. AJR Am J Roentgenol 185:64–71

    Article  PubMed  Google Scholar 

  • Goldberg SN, Dupuy DE (2001) Image-guided radiofrequency tumor ablation: challenges and opportunities – part I. J Vasc Interv Radiol 12:1021–1032

    Article  Google Scholar 

  • Goldberg SN, Gazelle GS, Mueller PR (2000) Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance. Am J Radiol 174:323–331

    CAS  Google Scholar 

  • Hakime A, Hines-Peralta AU, Peddy H et al (2007) Combination of radiofrequency ablation with antiangiogenic therapy for tumor ablation efficacy: study in mice. Radiology 244(2):464–470

    Article  PubMed  Google Scholar 

  • Herts BR, Baker ME (1995) The current role of percutaneous biopsy in the evaluation of renal masses. Semin Urol Oncol 13(4):254–261

    PubMed  CAS  Google Scholar 

  • Hoffmann NE, Bischof JC (2002) The cryobiology of cryosurgical injury. Urology 60:40–49

    Article  PubMed  Google Scholar 

  • Hollingsworth JM, Miller DC, Daignault S et al (2006) Rising incidence of small renal masses: a need to reassess treatment effect. J Natl Cancer Inst 98:1331–1334

    Article  PubMed  Google Scholar 

  • Horkan C et al (2005) Reduced tumor growth with combined radiofrequency ablation and radiation therapy in a rat breast tumor model. Radiology 235(1):81–88

    Article  PubMed  Google Scholar 

  • Hui GC, Tuncali K, Tatli S et al (2008) Comparison of percutaneous and surgical approaches to renal tumor ablation: metaanalysis of effectiveness and complication rates. J Vasc Interv Radiol 19(9):1311–1320

    Article  PubMed  Google Scholar 

  • Jayson M, Sanders H (1998) Increased incidence of serendipitously discovered renal cell carcinoma. Urology 51:203–205

    Article  PubMed  CAS  Google Scholar 

  • Jemal A, Siegel R, Ward E et al (2008) Cancer statistics, 2008. CA Cancer J Clin 58:71–96

    Article  PubMed  Google Scholar 

  • Johnson DB, Saboorian MH, Duchene DA et al (2003) Nephrectomy after radiofrequency ablation-induced ureteropelvic junction obstruction: potential complication and long-term assessment of ablation adequacy. Urology 62(2):351–352

    Article  PubMed  Google Scholar 

  • Johnson DB, Solomon SB, Su LM et al (2004) Defining the complications of cryoablation and radio frequency ablation of small renal tumors: a multi-institutional review. J Urol 172:874–877

    Article  PubMed  Google Scholar 

  • Kim EH, Tanagho YS, Bhayani SB et al (2013) Percutaneous cryoablation of renal masses: Washington University experience of treating 129 tumours. BJU 111(6):872–879

    Article  Google Scholar 

  • Klingler HC, Susani M, Seip R et al (2008) A novel approach to energy ablative therapy of small renal tumours: laparoscopic high-intensity focused ultrasound. Eur Urol 53(4):810–816

    Article  PubMed  Google Scholar 

  • Kunkle DA, Uzzo RG (2008) Cryoablation or radiofrequency ablation of the small renal mass: a meta-analysis. Cancer 113(10):2671–2680

    Article  PubMed  PubMed Central  Google Scholar 

  • Lenard ZM, McDannold NJ, Fennessy FM et al (2008) Uterine leiomyomas: MR imaging-guided focused ultrasound surgery – imaging predictors of success. Radiology 249(1):187–194

    Article  PubMed  PubMed Central  Google Scholar 

  • Levinson AW, Su LM, Agarwal D et al (2008) Long-term oncological and overall outcomes of percutaneous radio frequency ablation in high risk surgical patients with a solitary small renal mass. J Urol 180(2):499–504

    Article  PubMed  Google Scholar 

  • Liang P, Wang Y, Zhang D et al (2008) Ultrasound guided percutaneous microwave ablation for small renal cancer: initial experience. J Urol 180(3):844–848

    Article  PubMed  Google Scholar 

  • Liu Z, Ahmed M, Weinstein Y et al (2006) Characterization of the RF ablation-induced “oven effect”: the importance of background tissue thermal conductivity on tissue heating. Int J Hyperthermia 22(4):327–342

    Article  PubMed  Google Scholar 

  • Lokken RP, Gervais DA, Arellano RS et al (2007) Inflammatory nodules mimic applicator track seeding after percutaneous ablation of renal tumors. AJR Am J Roentgenol 189:845–848

    Article  PubMed  Google Scholar 

  • Lu DS, Raman SS, Vodopich DJ et al (2002) Effect of vessel size on creation of hepatic radiofrequency lesions in pigs: assessment of the “heat sink” effect. AJR Am J Roentgenol 178:47–51

    Article  PubMed  Google Scholar 

  • Mayo-Smith WW, Dupuy DE, Parikh PM et al (2003) Imaging-guided percutaneous radiofrequency ablation of solid renal masses; techniques and outcomes of 38 treatment sessions in 32 consecutive patients. AJR Am J Roentgenol 180:1503–1508

    Article  PubMed  Google Scholar 

  • McAchran SE, Lesani OA, Resnick MI (2005) Radiofrequency ablation of renal tumors: past, present, and future. Urology 66:15–22

    Article  PubMed  Google Scholar 

  • McLaughlin CA, Chen MY, Torti FM et al (2003) Radiofrequency ablation of isolated local recurrence of renal cell carcinoma after radical nephrectomy. AJR Am J Roentgenol 181:93–94

    Article  PubMed  Google Scholar 

  • Merkle EM, Nour SG, Lewin JS (2005) MR imaging follow-up after percutaneous radiofrequency ablation of renal cell carcinoma: findings in 18 patients during first 6 months. Radiology 235:1065–1071

    Article  PubMed  Google Scholar 

  • Ogan K, Jacomides L, Dolmatch BL et al (2002) Percutaneous radiofrequency ablation of renal tumors: technique, limitations, and morbidity. Urology 60(6):954–958

    Article  PubMed  Google Scholar 

  • Onishi T, Nishikawa K, Hasegawa Y et al (2007) Assessment of health-related quality of life after radiofrequency ablation or laparoscopic surgery for small renal cell carcinoma: a prospective study with medical outcomes Study 36-Item Health Survey (SF-36). Jpn J Clin Oncol 37:750–754

    Article  PubMed  Google Scholar 

  • Pandharipande PV, Gervais DA, Mueller PR et al (2008) Radiofrequency ablation versus nephron-sparing surgery for small unilateral renal cell carcinoma: cost-effectiveness analysis. Radiology 248(1):169–178

    Article  PubMed  Google Scholar 

  • Panumatrassamee K, Kaouk JH, Autorino R et al (2013) Cryoablation versus minimally invasive partial nephrectomy for small renal masses in the solitary kidney: impact of approach on functional outcomes. J Urol 189(3):818–822

    Article  PubMed  Google Scholar 

  • Rupp CC, Hoffmann NE, Schmidlin FR et al (2002) Cryosurgical changes in the porcine kidney: histologic analysis with thermal history correlation. Cryobiology 45:167–182

    Article  PubMed  Google Scholar 

  • Silverman SG, Gan YU, Mortele JK et al (2006) Renal masses in the adult patient: the role of percutaneous biopsy. Radiology 240(1):6–22

    Article  PubMed  Google Scholar 

  • Solazzo SA, Liu Z, Lobo SM et al (2005) Radiofrequency ablation: importance of background tissue electrical conductivity – an agar phantom and computer modeling study. Radiology 236(2):495–502

    Article  PubMed  Google Scholar 

  • Stein RJ, Kaouk JH (2007) Renal cryotherapy: a detailed review including a 5-year follow-up. BJU Int 99:1265–1270

    Article  PubMed  Google Scholar 

  • Tanaka K, Hara I, Takenaka A et al (2008) Incidence of local and port site recurrence of urologic cancer after laparoscopic surgery. Urology 71(4):728–734

    Article  PubMed  Google Scholar 

  • Warlick CA, Lima GC, Allaf ME et al (2006) Clinical sequelae of radiographic iceball involvement of collecting system during computed tomography-guided percutaneous renal tumor cryoablation. Urology 67(5):918–922

    Article  PubMed  Google Scholar 

  • Wertman R, Altun E, Martin DR et al (2008) Risk of nephrogenic systemic fibrosis: evaluation of gadolinium chelate contrast agents at four American universities. Radiology 248(3):799–806

    Article  PubMed  Google Scholar 

  • Wood BJ, Grippo J, Pavlovich CP (2001) Percutaneous radio frequency ablation for hematuria. J Urol 166:2303–2304

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Zagoria RJ, Chen MY, Kavanagh PV et al (2001) Radio frequency ablation of lung metastases from renal cell carcinoma. J Urol 166(5):1827–1828

    Article  PubMed  CAS  Google Scholar 

  • Zagoria RJ, Hawkins AD, Clark PE et al (2004) Percutaneous CT-guided radiofrequency ablation of renal neoplasms: factors influencing success. AJR Am J Roentgenol 183:201–207

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Beth Israel Deaconess Medical Center, 1 Deaconess Rd, Room CC308, Boston, MA, 02215, USA

    Andrew Hines-Peralta & S. Nahum Goldberg

  2. Department of Radiology, Cattinara Hospital, University of Trieste, Strada di Fiume 447, Trieste, 34149, Italy

    Emilio Quaia

  3. Department of Radiology, Ospedale Maggiore, Piazza Ospitale, 1, Trieste, 34123, Italy

    Fulvio Stacul

Authors
  1. Andrew Hines-Peralta
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Nahum Goldberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Emilio Quaia
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Fulvio Stacul
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Emilio Quaia .

Editor information

Editors and Affiliations

  1. Department of Radiology, Cattinara Hospital, University of Trieste, Trieste, Italy

    Emilio Quaia

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hines-Peralta, A., Goldberg, S.N., Quaia, E., Stacul, F. (2014). Radio-frequency Ablation and Cryoablation for Renal Cell Carcinoma. In: Quaia, E. (eds) Radiological Imaging of the Kidney. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54047-9_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-54047-9_23

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54046-2

  • Online ISBN: 978-3-642-54047-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation