Skip to main content
SpringerLink
Log in

Breast Augmentation with Stem Cell-Enhanced Fat Transfer: Comparison Between Enhanced and Unenhanced Fat Grafting

  • Chapter
  • First Online:
Stem Cells in Aesthetic Procedures

  • 1713 Accesses

Abstract

Recent advances in harvesting techniques and radiological imaging protocols have resulted in fat graft breast augmentation becoming an alternative to implant augmentation. Adipose-derived stem cells are well known for their regenerative and therapeutic properties and have the ability to differentiate along multiple lineage pathways. The subcutaneous adipose tissue is the largest reservoir of adipose-derived stem cells (ADSCs). Liposuction is thus a convenient method of obtaining large amounts of ADSCs and eliminates the need for tissue culturing. The authors discuss stem cell-enhanced fat graft breast augmentation and describe the technique for adipose-derived stem cell isolation for fat grafting.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Neuber F. Fettransplantation. Chir Kongr Verhandl Deutsche Gesellsch Chir. 1893;22:66.

    Google Scholar 

  2. Missana MC, Laurent I, Barreau L, Balleyguier C. Autologous fat transfer in reconstructive breast surgery: indications, technique and results. Eur J Surg Oncol. 2007;33(6):685–90.

    Article  CAS  PubMed  Google Scholar 

  3. Coleman SR, Saboeiro AP. Fat grafting to the breast revisited: safety and efficacy. Plast Reconstr Surg. 2007;119(3):775–85.

    Article  CAS  PubMed  Google Scholar 

  4. Carvajal J, Patiño JH. Mammographic findings after breast augmentation with autologous fat injection. Aesthet Surg J. 2008;28(2):153–62.

    Article  CAS  PubMed  Google Scholar 

  5. Delay E, Garson S, Tousson G, Sinna R. Fat injection to the breast: technique, results, and indications based on 880 procedures over 10 years. Aesthet Surg J. 2009;29(5):360–76.

    Article  PubMed  Google Scholar 

  6. Illouz YG, Sterodimas A. Autologous fat transplantation to the breast: a personal technique with 25 years of experience. Aesthetic Plast Surg. 2009;33(5):706–15.

    Article  PubMed  Google Scholar 

  7. Veber M, Tourasse C, Toussoun G, Moutran M, Mojallal A, Delay E. Radiographic findings after breast augmentation by autologous fat transfer. Plast Reconstr Surg. 2011;127(3):1289–99.

    Article  CAS  PubMed  Google Scholar 

  8. Fraser JK, Hedrick MH, Cohen SR. Oncologic risks of autologous fat grafting to the breast. Aesthet Surg J. 2011;31(1):68–75.

    Article  PubMed  Google Scholar 

  9. Claro F, Figueiredo JC, Zampar AG, Pinto-Neto AM. Applicability and safety of autologous fat for reconstruction of the breast. Br J Surg. 2012;99(6):768–80.

    Article  PubMed  Google Scholar 

  10. Akita S, Yoshimoto H, Ohtsuru A, Hirano A, Yamashita S. Autologous adipose-derived regenerative cells are effective for chronic intractable radiation injuries. Radiat Prot Dosimetry. 2012;151(4):656–60.

    Article  CAS  PubMed  Google Scholar 

  11. Zhu M, Zhou Z, Chen Y, Schreiber R, Ransom JT, Fraser JK, Hedrick MH, Pinkernell K, Kuo HC. Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention. Ann Plast Surg. 2010;64(2):222–8.

    Article  CAS  PubMed  Google Scholar 

  12. Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K. Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem/stromal cells. Aesthetic Plast Surg. 2008;32(1):48–55.

    Article  PubMed Central  PubMed  Google Scholar 

  13. Yoshimura K, Shigeura T, Matsumoto D, Sato T, Takaki Y, Aiba-Kojima E, Sato K, Inoue K, Nagase T, Koshima I, Gonda K. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J Cell Physiol. 2006;208(1):64–76.

    Article  CAS  PubMed  Google Scholar 

  14. Katz AJ, Hedrick MH, Llull R, Futrell JW. A novel device for the simple and efficient refinement of liposuctioned tissue. Plast Reconstr Surg. 2001;107(2): 595–7.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Hospital Group, London, 98, Harley Street, London, W1G 7HZ, UK

    Alberto di Giuseppe M.D.

  2. Department of Plastic and Reconstructive Surgery, Marche Polytechnic University Medical School, University of Ancona, Via Simeoni, 6, Ancona, 60122, Italy

    Alberto di Giuseppe M.D.

  3. The Private Clinic Group, London, 98, Harley Street, London, W1G 7HZ, UK

    Dennis Wolf M.D.

Authors
  1. Alberto di Giuseppe M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dennis Wolf M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alberto di Giuseppe M.D. .

Editor information

Editors and Affiliations

  1. Section of Surgery, Newport Specialty Hospital, Tustin, California, USA

    Melvin A. Shiffman

  2. Department of Plastic and Reconstructive Surgery, Marche Polytechnic University Medical School, University of Ancona, Ancona, Italy

    Alberto Di Giuseppe

  3. Department of Plastic Surgery, University of Padova, Padova, Italy

    Franco Bassetto

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

di Giuseppe, A., Wolf, D. (2014). Breast Augmentation with Stem Cell-Enhanced Fat Transfer: Comparison Between Enhanced and Unenhanced Fat Grafting. In: Shiffman, M., Di Giuseppe, A., Bassetto, F. (eds) Stem Cells in Aesthetic Procedures. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45207-9_37

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-45207-9_37

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45206-2

  • Online ISBN: 978-3-642-45207-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation