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Facial Rejuvenation with Stem Cell Fat Graft: The FAMI™ Procedure

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Stem Cells in Aesthetic Procedures

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Abstract

Facial fat grafting has been largely limited to the subcutaneous plane with vague reference to injecting into the muscular planes. The FAMI™ technique described herein specifically targets tissue planes and the individual muscles of facial expression to engraft adipose tissue and the mesenchymal cells within lipoaspirates. Graft survival, predictability, and symmetry are greatly enhanced by targeting the rich vascular bed of the muscles of facial expression. Augmenting regressed bony surfaces with subperiosteal injections as well as the deep and subcutaneous fat pads leads to a more natural restoration of youthful contours and volumes.

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References

  1. Neuber F. Fettransplantation. Bericht über die Verhandlungen der deutschen Gesellschaft für Chirurgie. Zentralbl Chir. 1893;22:66.

    Google Scholar 

  2. Lexer E. Fett transplantation. Dtsch Med Wochenschr. 1910;36:640.

    Google Scholar 

  3. Illouz YG. The fat cell “graft”: a new technique to fill depressions. Plast Reconstr Surg. 1986;78(1):122–3.

    Article  CAS  PubMed  Google Scholar 

  4. Fournier PF. Microlipoextraction et microlipoinjection. Rev Chir Esthét Lang Fr. 1985;10:40.

    Google Scholar 

  5. Carraway JH, Mellow CG. Syringe aspiration and fat concentration: a simple technique for autologous fat injection. Ann Plast Surg. 1990;24(3):293–6.

    Article  CAS  PubMed  Google Scholar 

  6. Coleman 3rd WP. Autologous fat transplantation. Plast Reconstr Surg. 1991;88(4):736.

    Article  PubMed  Google Scholar 

  7. Bircoll M, Novack BH. Autologous fat transplantation employing liposuction techniques. Ann Plast Surg. 1987;18(4):327–9.

    Article  CAS  PubMed  Google Scholar 

  8. Ellenbogen R. Free autogenous pearl fat grafts in the face–a preliminary report of a rediscovered technique. Ann Plast Surg. 1986;16(3):179–94.

    Article  CAS  PubMed  Google Scholar 

  9. Matsudo PK, Toledo LS. Experience of injected fat grafting. Aesthetic Plast Surg. 1988;12(1):35–8.

    Article  CAS  PubMed  Google Scholar 

  10. Coleman SR. Facial augmentation with structural fat grafting. Clin Plast Surg. 2006;33(4):567–77.

    Article  PubMed  Google Scholar 

  11. Amar RE. Adipocyte microinfiltration in the face or tissue restructuration with fat tissue graft. Ann Chir Plast Esthet. 1999;44(6):593–608.

    CAS  PubMed  Google Scholar 

  12. Nguyen A, Pasyk KA, Bouvier TN, Hassett CA, Argenta LC. Comparative study of survival of autologous adipose tissue taken and transplanted by different techniques. Plast Reconstr Surg. 1990;85(3):378–86.

    Article  CAS  PubMed  Google Scholar 

  13. Guerrerosantos J, Gonzalez-Mendoza A, Masmela Y, Gonzalez MA, Deos M, Diaz P. Long-term survival of free fat grafts in muscle: an experimental study in rats. Aesthetic Plast Surg. 1996;20(5):403–8.

    Article  CAS  PubMed  Google Scholar 

  14. Murillo WL. Buttock augmentation: case studies of fat injection monitored by magnetic resonance imaging. Plast Reconstr Surg. 2004;114(6):1606–14.

    Article  PubMed  Google Scholar 

  15. Coleman SR. Facial recontouring with lipostructure. Clin Plast Surg. 1997;24(2):347–67.

    CAS  PubMed  Google Scholar 

  16. Fournier PF. Fat grafting: my technique. Dermatol Surg. 2000;26(12):1117–28.

    Article  CAS  PubMed  Google Scholar 

  17. Mizuno H, Zuk PA, Zhu M, Lorenz HP, Benhaim P, Hedrick MH. Myogenic differentiation by human processed lipoaspirate cells. Plast Reconstr Surg. 2002;109(1):199–209.

    Article  PubMed  Google Scholar 

  18. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell. 2002;13(12):4279–95.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  19. Bacou F, el Andalousi RB, Daussin PA, Micallef JP, Levin JM, Chammas M, Casteilla L, Reyne Y, Nouguès J. Transplantation of adipose tissue-derived stromal cells increases mass and functional capacity of damaged skeletal muscle. Cell Transplant. 2004;13(2):103–11.

    PubMed  Google Scholar 

  20. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 2001;7(2):211–28.

    Article  CAS  PubMed  Google Scholar 

  21. Coleman SR. Structural fat grafts: the ideal filler? Clin Plast Surg. 2001;28(1):111–9.

    CAS  PubMed  Google Scholar 

  22. Birk RZ, Abramovitch-Gottlib L, Margalit I, Aviv M, Forti E, Geresh S, Vago R. Conversion of adipogenic to osteogenic phenotype using crystalline porous biomatrices of marine origin. Tissue Eng. 2006;12(1):21–31.

    Article  CAS  PubMed  Google Scholar 

  23. Toledo LS. Syringe liposculpture: a two-year experience. Aesthetic Plast Surg. 1991;15(4):321–6.

    Article  CAS  PubMed  Google Scholar 

  24. Jauffret JL, Champsaur P, Robaglia-Schlupp A, Andrac-Meyer L, Magalon G. Arguments in favor of adipocyte grafts with the S.R. Coleman technique. Ann Chir Plast Esthet. 2001;46(1):31–8.

    Article  CAS  PubMed  Google Scholar 

  25. Pessa JE, Zadoo VP, Yuan C, Ayedelotte JD, Cuellar FJ, Cochran CS, Mutimer KL, Garza JR. Concertina effect and facial aging: nonlinear aspects of youthfulness and skeletal remodeling, and why, perhaps, infants have jowls. Plast Reconstr Surg. 1999;103(2):635–44.

    Article  CAS  PubMed  Google Scholar 

  26. Lambros VS. What age(s) for face lifts? Plast Reconstr Surg. 1999;103(3):1076.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Marbella Aesthetic Clinic (Amar Clinic), Edificio King Edward, Of.106, C/ Ramôn Gômez De La Serna, 22, 29602, Marbella, Spain

    Roger E. Amar M.D.

Authors
  1. Roger E. Amar M.D.
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Correspondence to Roger E. Amar M.D. .

Editor information

Editors and Affiliations

  1. Section of Surgery, Newport Specialty Hospital, Tustin, California, USA

    Melvin A. Shiffman

  2. Department of Plastic and Reconstructive Surgery, Marche Polytechnic University Medical School, University of Ancona, Ancona, Italy

    Alberto Di Giuseppe

  3. Department of Plastic Surgery, University of Padova, Padova, Italy

    Franco Bassetto

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Amar, R.E. (2014). Facial Rejuvenation with Stem Cell Fat Graft: The FAMI™ Procedure. In: Shiffman, M., Di Giuseppe, A., Bassetto, F. (eds) Stem Cells in Aesthetic Procedures. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45207-9_28

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  • DOI: https://doi.org/10.1007/978-3-642-45207-9_28

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45206-2

  • Online ISBN: 978-3-642-45207-9

  • eBook Packages: MedicineMedicine (R0)

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