Zusammenfassung
Hyperlipidämien (Synonym: Hyperlipoproteinämien) sind biochemische Veränderungen, bei denen ein oder mehrere Anteile der Serumlipide (Cholesterin, Triglyceride oder beide) und eines oder mehrere der diese Lipide transportierenden Lipoproteine vermehrt sind. Bei den meisten sind multiple genetische und/oder exogene Faktoren kausal beteiligt; bei manchen wird die Hyperlipoproteinämie durch einen ganz bestimmten Gendefekt, der den Lipidmetabolismus beeinflussen kann, verursacht. Epidemiologische Studien haben den Beweis erbracht, dass ein direkter Zusammenhang zwischen der Serumcholesterinkonzentration und der Häufigkeit des Auftretens von atherosklerotischen Gefäßveränderungen besteht.
Atherosklerose stellt nach wie vor die weitaus überwiegende Ursache der Koronargefäßerkrankung dar. Etwa die Hälfte der Todesfälle in Europa wird mittelbar oder unmittelbar durch diese Krankheit verursacht.
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Notes
- 1.
Umrechnung: mg/dl × 0,01 = g/l.
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Widhalm, K. (2014). Hyperlipoproteinämien. In: Hoffmann, G., Lentze, M., Spranger, J., Zepp, F. (eds) Pädiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41866-2_55
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