Skip to main content

Zusammenfassung

Beim Hodgkin-Lymphom handelt es sich um maligne Neoplasien des lymphatischen Gewebes, bei der typischerweise Keimzentrum-B-Zellen im Lymphknoten entarten und in der Biopsie als multinukleäre Sternberg-Reed- oder einzellige Hodgkin-Riesenzellen nachgewiesen werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 179.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Bhatia S, Robison LL, Oberlin O et al. (1996) Breast cancer and other second neoplasms after childhood Hodgkin’s disease. N Engl J Med 334: 745–751

    Article  CAS  PubMed  Google Scholar 

  • Brämswig JH, Heimes U, Heiermann E et al. (1990) The effects of different cumulative doses of chemotherapy on testicular function. Results in 75 patients treated for Hodgkin’s disease during childhood or adolescence. Cancer 65: 1298–1302

    Article  PubMed  Google Scholar 

  • Dieckmann K, Potter R, Wagner W et al. (2002) Up-front centralized data review and individualized treatment proposals in a multicenter pediatric Hodgkin’s disease trial with 71 participating hospitals: the experience of the German-Austrian pediatric multicenter trial DAL-HD-90. Radiother Oncol 62: 191–200

    Article  PubMed  Google Scholar 

  • Dorffel W, Albrecht M, Luders H et al. (1998) Multi-national therapy study for Hodgkin’s disease in children and adolescents GPOH-DH 95. Interim report after 2 1/2 years Klin Padiatr 210: 212–219

    Article  CAS  PubMed  Google Scholar 

  • Gerres L, Bramswig JH, Schlegel W, Jurgens H, Schellong G (1998) The effects of etoposide on testicular function in boys treated for Hodgkin’s disease. Cancer 83:217–2222

    Article  Google Scholar 

  • Mauz-Körholz C, Gorde-Grosjean S, Hasenclever D et al. (2007) Resection alone in 58 children with limited stage, lymphocyte-predominant Hodgkin lymphoma-experience from the European network group on pediatric Hodgkin lymphoma. Cancer 110: 179–185

    Article  PubMed  Google Scholar 

  • Mauz-Körholz C, Hasenclever D, Dörffel W et al. (2010) Procarbazine-free OEPA-COPDAC chemotherapy in boys and standard OPPA-COPP in girls have comparable effectiveness in pediatric Hodgkin’s lymphoma: the GPOH-HD-2002 study. J Clin Oncol 10: 3680–3686

    Article  Google Scholar 

  • Purz S, Mauz-Körholz C, Körholz D et al. (2011) Fluorodeoxyglucose positron emission tomography for detection of bone marrow involvement in children and adolescents with Hodgkin’s lymphoma. J Clin Oncol 29: 3523–3528

    Article  PubMed  Google Scholar 

  • Schellong G, Bramswig J, Ludwig R et al. (1986) Combined treatment strategy in over 200 children with Hodgkin’s disease: graduated chemotherapy, involved field irradiation with low dosage and selective splenectomy. A report of the cooperative therapy study DAL-HD-82. Klin Padiatr 198: 137–146

    Article  CAS  PubMed  Google Scholar 

  • Schellong G, Hörnig I, Brämswig J et al. (1988) Zur Bedeutung des Procarbazins in der Chemotherapie des Morbus Hodgkin – Ein Bericht der kooperativen Therapiestudie DAL-HD-85. Klin Pädiatr 200: 205–213

    Article  CAS  PubMed  Google Scholar 

  • Schellong G, Potter R, Bramswig J et al. (1999) High cure rates and reduced long-term toxicity in pediatric Hodgkin’s disease: the German-Austrian multicenter trial DAL-HD-90. The German-Austrian Pediatric Hodgkin’s Disease Study Group. J Clin Oncol 17: 3736–3744

    CAS  PubMed  Google Scholar 

  • Schellong G, Riepenhausen M, Bruch C et al. (2010) Late valvular and other cardiac diseases after different doses of mediastinal radiotherapy for Hodgkin disease in children and adolescents: report from the longitudinal GPOH follow-up project of the German-Austrian DAL-HD studies. Pediatr Blood Cancer 55: 1145–1152

    Article  PubMed  Google Scholar 

  • Trieu Y, Wen XY, Skinnider BF et al. (2004) Soluble interleukin 13 alpha-2 decoy receptor inhibits Hodgkin’s lymphoma growth in vitro and in vivo. Cancer Res 64: 3271–3275

    Article  CAS  PubMed  Google Scholar 

  • Urayama KY, Jarrett RF, Hjalgrim H et al. (2012)Genome-wide association study of classical Hodgkin’s Lymphoma and Epstein-Barr Virus status-defined subgroups. J Natl. Cancer Institute 104: 240–253

    Article  CAS  Google Scholar 

  • Westergaard T, Melbye M, Pedersen JB et al. (1997) Birth order, sibship size and risk of Hodgkin’s disease in children and young adults: a population-based study of 31 million person-years. Int J Cancer 72: 977–981

    Article  CAS  PubMed  Google Scholar 

  • Younes A, Bartlett NL, Leonard JP et al. (2010) Brentuximab vedotin (SGN-35) for relapsed CD30 positive Lymphomas. N Engl J Med 363: 1812–1821

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Körholz, D., Müller, C.M. (2014). Hodgkin-Lymphom. In: Reinhardt, D., Nicolai, T., Zimmer, KP. (eds) Therapie der Krankheiten im Kindes- und Jugendalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41814-3_55

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-41814-3_55

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-41813-6

  • Online ISBN: 978-3-642-41814-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics