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Pathology of Gallbladder Cancer

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Biliary Tract and Gallbladder Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Gallbladder cancer is an uncommon cancer of gastrointestinal tract. Adenocarcinoma is the most common type of cancer to arise within the gallbladder and is typically associated with two precursor lesions: flat dysplasia and adenomas. Intracystic papillary neoplasms and mucinous cystic neoplasms are less common precursor lesions. The prognosis of patients with gallbladder carcinoma is highly dependent on tumor stage. Non-invasive and minimally invasive adenocarcinomas are typically cured with cholecystectomy and hence precise pathologic staging is critical for management and prognostication. Other less common variants of gallbladder carcinoma include adenosquamous carcinoma, squamous cell carcinoma, carcinosarcoma, and undifferentiated carcinoma and are typically associated with a worse prognosis. Neuroendocrine neoplasmas, lymphomas, and mesenchymal neoplasms of the gallbladder, as well as metastases, are extremely rare.

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Author information

Authors and Affiliations

  1. Department of Pathology, Massachusetts General Hospital, Boston, USA

    Vikram Deshpande

  2. Harvard Medical School, Massachusetts General Hospital, Boston, USA

    Andrea Primiani

Authors
  1. Vikram Deshpande
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  2. Andrea Primiani
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Corresponding author

Correspondence to Vikram Deshpande .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland, USA

    Joseph M. Herman

  2. Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA

    Timothy M. Pawlik

  3. Department of Radiation Oncology, Oregon Health and Science University, Portland, Oregon, USA

    Charles R. Thomas, Jr.

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© 2014 Springer-Verlag Berlin Heidelberg

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Deshpande, V., Primiani, A. (2014). Pathology of Gallbladder Cancer. In: Herman, J., Pawlik, T., Thomas, Jr., C. (eds) Biliary Tract and Gallbladder Cancer. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40558-7_3

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  • DOI: https://doi.org/10.1007/978-3-642-40558-7_3

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-40557-0

  • Online ISBN: 978-3-642-40558-7

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