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Platelet Rich Plasma (PRP) in Osteoarthritis

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Platelet-Rich Plasma

Part of the book series: Lecture Notes in Bioengineering ((LNBE))

Abstract

Articular cartilage has limited intrinsic healing potential. Trauma and/or chronic irritation may lead to progressive damage, joint degeneration and early OA. The purpose of this study was to determine the efficacy of the use of platelet rich plasma (PRP) obtained from a simple autologous blood extraction in the degenerative lesions of the knee. Prospectively 80 patients with degenerative lesions of the knee were followed up, with a minimum follow up of 12 months. All patients were treated with 2 intra-articular injections at monthly interval with autologous PRP. Knee evaluation scores were collected at pre-injection, 6 and 12 months post treatment. Patients showed significant improvement in all scores at final follow-up (p < 0.005). There was no significant difference in improvement between males and females. The use of PRP could act as a new hope as a preventive agent in patients with chronic and degenerative disease of the knee by diminishing pain and improving symptoms and quality of life.

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Authors and Affiliations

  1. O.A.S.I Bioresearch Foundation, Gobbi N.P.O., Via GA Amadeo 24, 20133, Milan, Italy

    Alberto Gobbi, Georgios Karnatzikos, Somanna Malchira & Anup Kumar

Authors
  1. Alberto Gobbi
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  2. Georgios Karnatzikos
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  3. Somanna Malchira
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  4. Anup Kumar
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Corresponding author

Correspondence to Alberto Gobbi .

Editor information

Editors and Affiliations

  1. Research Institute of Sports Medicine, Orthopedics and Regeneration - iMOR, Uberaba, Brazil

    José Fábio Santos Duarte Lana

  2. Department of Biotechnological Processes, University of Campinas, Campinas, Brazil

    Maria Helena Andrade Santana

  3. Department of Orthopaedic and Traumatology, University of Campinas, Campinas, Brazil

    William Dias Belangero

  4. Haematology and Hemotherapy Center, State University of Campinas, Campinas, Brazil

    Angela Cristina Malheiros Luzo

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© 2014 Springer-Verlag Berlin Heidelberg

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Gobbi, A., Karnatzikos, G., Malchira, S., Kumar, A. (2014). Platelet Rich Plasma (PRP) in Osteoarthritis. In: Lana, J., Andrade Santana, M., Dias Belangero, W., Malheiros Luzo, A. (eds) Platelet-Rich Plasma. Lecture Notes in Bioengineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40117-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-40117-6_11

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-40116-9

  • Online ISBN: 978-3-642-40117-6

  • eBook Packages: EngineeringEngineering (R0)

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