Abstract
A 93-year-old woman reported a 1-month history of left nipple irritation and of a lump in the left breast. On examination she had a 5 mm by 10 mm mass in the left lower inner quadrant. Mammogram (M5) demonstrated a 21-mm mass, while ultrasound (U5) revealed a 19-mm lesion of the left lower inner quadrant. Core biopsy showed grade 1 invasive ductal carcinoma. The lesion was oestrogen receptor positive with a Quick score of 8, progesterone receptor positive with a Quick score of 8 and HER2 negative.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ashamalla H, Cardoso E, Macedon M, Guirguis A, Weng L, Ali S et al (2009) Phase I trial of vertebral intracavitary cement and samarium (VICS): novel technique for treatment of painful vertebral metastasis. Int J Radiat Oncol Biol Phys 75:836–842
Chen AM, Obedian E, Haffty BG (2001) Breast-conserving therapy in the setting of collagen vascular disease. Cancer J 7:480–491
CRDM Technical Services (2008) Therapeutic radiation. Medtronic Incorporated, Mounds View
European Technical Services (2004) Impact of therapeutic radiation and guidant ICD/CRT-p/pacing systems review. Guidant Corp, St. Paul, pp 1–6
Hancock SL, Hoppe RT (1996) Long-term complications of treatment and causes of mortality after Hodgkin’s disease. Semin Radiat Oncol 6:225–242
Hudson F et al (2010) Effect of radiation therapy on the latest generation of pacemakers and implantable cardioverter defibrillators: a systematic review. J Med Imaging Radiat Oncol 54(1):53–61
Hughes KS, Schnaper LA, Berry D, Cirrincione C, McCormick B, Shank B (2004) Lumpectomy plus tamoxifen with or without irradiation in women age 70 or older with early breast cancer. N Engl J Med 351:971–977
Keshtgar MR, Vaidya JS, Tobias JS, Wenz F, Joseph D, Stacey C et al (2011) Targeted intraoperative radiotherapy for breast cancer in patients in whom external beam radiotherapy is not possible. J Radiat Oncol Biol Phys 80:31–38
Marbach JR et al (1994) Management of radiation oncology patients with implanted cardiac pacemakers: report of AAPM Task Group No. 34. American Association of Physicists in Medicine. Med Phys 21(1):85–90
Mouton J et al (2002) Influence of high-energy photon beam irradiation on pacemaker operation. Phys Med Biol 47(16):2879–2893
Reis T, Schneider F, Welzel G, Schmidt R, Bludau F, Obertacke U, Wenz F (2012) Intraoperative radiotherapy during kyphoplasty for vertebral metastases (Kypho IORT): first clinical results. Tumori 98:434–440
Rhythm Management Division (2005) Radiation. St. Jude Medical, Sylmar
Rutkowski T et al (2010) Intraoperative radiotherapy (IORT) with low-energy photons as a boost in patients with early-stage oral cancer with the indications for postoperative radiotherapy: treatment feasibility and preliminary results. Strahlenther Onkol 186(9):496–501
Swerdlow AJ, Douglas AJ, Hudson GV, Hudson BV, Bennett MH, MacLennan KA (1992) Risk of second primary cancers after Hodgkin’s disease by type of treatment: analysis of 2846 patients in the British National Lymphoma Investigation. BMJ 304:1137–114
Schmidt R, Wenz F, Reis T, Janik K, Bludau F, Obertacke U (2012) Kyphoplasty and intra-operative radiotherapy, combination of kyphoplasty and intra-operative radiation for spinal metastases: technical feasibility of a novel approach. Int Orthop 36:1255–1260
Schneider F, Greineck F, Clausen S, Mai S, Obertacke U, Reis T, Wenz F (2011) Development of a novel method for intraoperative radiotherapy during kyphoplasty for spinal metastases (Kypho-IORT). Int J Radiat Oncol Biol Phys 81:1114–1119
Souchon R, Wenz F, Sedlmayer F, Budach W, Dunst J, Feyer P et al (2009) DEGRO practice guidelines for palliative radiotherapy of metastatic breast cancer: bone metastases and metastatic spinal cord compression (MSCC). Strahlenther Onkol 185:417–424
Travis LB, Hill D, Dores GM, Gospodarowicz M, van Leeuwen FE, Holowaty E et al (2005) Cumulative absolute breast cancer risk for young women treated for Hodgkin lymphoma. J Natl Cancer Inst 97:1428–1437
Vaidya JS, Joseph DJ, Tobias JS, Bulsara M, Wenz F, Saunders C et al (2010) Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority, randomised, non-inferiority phase 3 trial. Lancet 376:91–102
Wo J, Taghian A (2007) Radiotherapy in setting of collagen vascular disease. Int J Radiat Oncol Biol Phys 69:1347–1353
Wolmark N, Dignam J, Margolese R, Wickerham DL, Fisher B (2000) The role of radiotherapy and tamoxifen in the management of node negative invasive breast cancer <1.0 cm treated with lumpectomy: preliminary results of NSABP protocol B-21. Proc Am Soc Clin Oncol 19:70a, Abstract 271
Van der Linden E, Kroft LJ, Dijkstra PD (2007) Treatment of vertebral tumor with posterior wall defect using image-guided radiofrequency ablation combined with vertebroplasty: preliminary results in 12 patients. J Vasc Interv Radiol 18:741–747
Yang Z, Yang D, Xie L, Sun Y, Huang Y, Sun H et al (2009) Treatment of metastatic spinal tumours by percutaneous vertebroplasty versus percutaneous vertebroplasty combined with interstitial implantation of 125I seeds. Acta Radiol 50:1142–1148
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Pigott, K. et al. (2014). Case Reports. In: Keshtgar, M., Pigott, K., Wenz, F. (eds) Targeted Intraoperative Radiotherapy in Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39821-6_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-39821-6_15
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-39820-9
Online ISBN: 978-3-642-39821-6
eBook Packages: MedicineMedicine (R0)