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Melanocytic Nevus with Phenotypic Heterogeneity: Combined Melanocytic Nevus and Variants

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Pathology of Melanocytic Nevi and Melanoma

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Abstract

The term melanocytic nevus with phenotypic heterogeneity (MNPH), as originally introduced in the first edition of this monograph, connotes both qualitatively and quantitatively the wide range of neurocristic phenotypic differentiation which may be observed in melanocytic neoplasms [1]. Thus, MNPH is a generic term used to describe two or more distinct nevus cellular elements, or lines of neural crest differentiation, in a single melanocytic nevus, as, e.g., MNPH with components of compound dysplastic nevus and common blue nevus or MNPH with congenital-nevus component and sclerosing spindle cell component with Schwannian differentiation.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at the University of California, Los Angeles, USA

    Raymond L. Barnhill MD, MSc

  2. Jonsson Comprehensive Cancer Center, 10833 Le Conte Ave., AS-370 CHS, Los Angeles, CA, 90095, USA

    Raymond L. Barnhill MD, MSc

Authors
  1. Raymond L. Barnhill MD, MSc
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Correspondence to Raymond L. Barnhill MD, MSc .

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Editors and Affiliations

  1. UCLA and Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California, USA

    Raymond L. Barnhill

  2. University of Washington and Dermatopathology Northwest PLLC, Bellevue, Washington, USA

    Michael W. Piepkorn

  3. Memorial Sloan Kettering Cancer Center, New York, New York, USA

    Klaus J. Busam

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Barnhill, R.L. (2014). Melanocytic Nevus with Phenotypic Heterogeneity: Combined Melanocytic Nevus and Variants. In: Barnhill, R., Piepkorn, M., Busam, K. (eds) Pathology of Melanocytic Nevi and Melanoma. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38385-4_9

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  • DOI: https://doi.org/10.1007/978-3-642-38385-4_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-38384-7

  • Online ISBN: 978-3-642-38385-4

  • eBook Packages: MedicineMedicine (R0)

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