Zusammenfassung
Bei erfolgter Sicherung eines Papillenkarzinoms – auch bei kleinen Tumoren – stellt die partielle Duodenopankreatektomie mit Lymphadenektomie das chirurgische Verfahren der Wahl dar. Meist kann pyloruserhaltend und insgesamt mit einer Mortalität von deutlich unter 5 % operiert werden. Damit können 5- und 10-Jahres-Überlebensraten von bis zu 60 % bzw. 30 % erzielt werden.
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Literatur
Baczako K, Büchler M, Beger HG et al (1985) Morphogenesis and possible precursors lesions of invasive carcinoma of the papilla of Vater: epithelial dysplasia and adenoma. Hum Pathol 16: 305–310
Beger HG, Thorab FC, Liu Z et al (2004) Pathogenesis and treatment of neoplastic diseases of the papilla of Vater: Kausch-Whipple procedure with lymph node dissection in cancer of the papilla of Vater. J Hepatobiliary Pancreat Surg 11(4): 232–238
Beger HG, Treitschke F, Gansauge F et al (1999) Tumor of the ampulla of Vater: experience with local or radical resection in 171 consecutively treated patients. Arch Surg 134(5): 526–532
Berberat PO, Künzli BM, Gulbinas A et al (2009) An audit of outcomes of a series of periampullary carcinomas. Eur J Surg Oncol 35(2): 187–191
van der Gaag NA, Rauws EA, van Eijck CH et al (2010) Preoperative biliary drainage for cancer of the head of the pancreas. N Engl J Med 362(2): 129–137
Heinrich S, Clavien PA (2010) Ampullary cancer. Curr Opin Gastroenterol 26: 280–285
Klein P, Reingruber B, Kastl S, Dworak O, Hohenberger W (1996) Is local excision of pT1-ampullary carcinomas justified? Eur J Surg Oncol 22(4): 366–371
Matsumoto T, Iida M, Nakamura S et al (2000) Natural history of ampullary adenomain familial adenomatous polyposis: reconfirmation of benign nature during extended surveillance. Am J Gastroenterol 95: 1557–1562
Neoptolemos JP, Talbot IC, Carr-Locke DL et al (1987) Treatment and outcome in 52 consecutive cases of ampullary carcinoma. Br J Surg 74(10): 957–961
Riall TS, Cameron JL, Lillemoe KD et al (2006) Resected periampullary adenocarcinoma: 5-year survivors and their 6- to 10-year follow-up. Surgery 140(5): 764–772
Sharp KW, Brandes JL (1990) Local resection of tumors of the ampulla of Vater. Am Surg 56(4): 214–217
Sommerville CA, Limongelli P, Pai M et al (2009) Survival analysis after pancreatic resection for ampullary and pancreatic head carcinoma: an analysis of clinicopathological factors. J Surg Oncol 100(8): 651–656
Talamini MA, Moesinger RC, Pitt HA et al (1997) Adenocarcinoma of the ampulla of Vater. A 28-year experience. Ann Surg 225(5): 590–599
Westgaard A, Tafjord S, Farstad IN et al (2008) Pancreatobiliary versus intestinal histologic type of differentiation is an independent prognostic factor in resected periampullary adenocarcinoma. BMC Cancer 11(8): 170
Winter JM, Cameron JL, Olino K et al (2010) Clinicopathologic analysis of ampullary neoplasms in 450 patients: implications for surgical strategy and long-term prognosis. J Gastrointest Surg 14(2): 379–387
Yeh CC, Jeng YM, Ho CM et al (2010) Survival after pancreaticoduodenectomy for ampullary cancer is not affected by age. World J Surg 34(12): 2945–2952
Yeo CJ, Sohn TA, Cameron JL et al (1998) Periampullary adenocarcinoma: analysis of 5-year survivors. Ann Surg 227(6): 821–831
Zhou H, Schaefer N, Wolff M, Fischer HP (2004) Carcinoma of the ampulla of Vater: comparative histologic/immunohistochemical classification and follow-up. Am J Surg Pathol 28(7): 875–882
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Tjaden, C., Hackert, T. (2013). Das Papillenkarzinom: Evidenz der operativen Entfernung. In: Beger, H., et al. Erkrankungen des Pankreas. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37964-2_84
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