Skip to main content

Surgical Treatment of Osteochondral Defects of the Knee with Mosaicplasty Technique

  • Living reference work entry
  • First Online:
Sports Injuries

Abstract

Mosaicplasty involves the transplantation of one or more cylindrical plugs harvested from less weight-bearing periphery of the articular surface of the femoral condyle. The procedure can be done open or arthroscopically; however, it is crucial to maintain a perpendicular graft orientation and match the articular surface contour. Plugs should also be matched to the depth of the recipient site. Multiple clinical studies have demonstrated good-to-excellent results in short- to midterm follow-up. Positive prognostic factors include smaller lesion size, shorter preoperative duration of symptoms, no prior surgical treatment, younger patient age, and a higher preinjury level of sports. Imaging studies and second-look arthroscopy have also confirmed good integration and maintenance of grafted cartilage. However, patients must be counseled on potential complications including fibrous overgrowth, graft subsidence, chondrocyte death, deep venous thrombosis, intra-articular bleeding, and infection.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Ahmad CS, Cohen ZA et al (2001) Biomechanical and topographic considerations for autologous osteochondral grafting in the knee. Am J Sports Med 29(2):201–206

    CAS  PubMed  Google Scholar 

  • Bader S, Miniaci A (2011) Mosaicplasty. Orthopedics 34(9):e491–e493

    PubMed  Google Scholar 

  • Bartz RL, Kamaric E et al (2001) Topographic matching of selected donor and recipient sites for osteochondral autografting of the articular surface of the femoral condyles. Am J Sports Med 29(2):207–212

    CAS  PubMed  Google Scholar 

  • Bedi A, Feeley BT et al (2010) Management of articular cartilage defects of the knee. J Bone Joint Surg 92(4):994–1009

    Article  PubMed  Google Scholar 

  • Breinan HA, Martin SD et al (2000) Healing of canine articular cartilage defects treated with microfracture, a type-II collagen matrix, or cultured autologous chondrocytes. J Orthop Res Off Publ Orthop Res Soc 18(5):781–789

    Article  CAS  Google Scholar 

  • Brittberg M (2008) Autologous chondrocyte implantation – technique and long-term follow-up. Injury 39(Suppl 1):S40–S49

    Article  PubMed  Google Scholar 

  • Brittberg M, Peterson L et al (2003) Articular cartilage engineering with autologous chondrocyte transplantation. A review of recent developments. J Bone Joint Surg 85-A(Suppl 3):109–115

    PubMed  Google Scholar 

  • Browne JE, Branch TP (2000) Surgical alternatives for treatment of articular cartilage lesions. J Am Acad Orthop Surg 8(3):180–189

    CAS  PubMed  Google Scholar 

  • Chung CB Frank LR et al (2001) Cartilage imaging techniques: current clinical applications and state of the art imaging. Clin Orthop Relat Res (391 Suppl):S370–S378

    Google Scholar 

  • Duchow J, Hess T et al (2000) Primary stability of press-fit-implanted osteochondral grafts. Influence of graft size, repeated insertion, and harvesting technique. Am J Sports Med 28(1):24–27

    CAS  PubMed  Google Scholar 

  • Evans PJ, Miniaci A et al (2004) Manual punch versus power harvesting of osteochondral grafts. Arthrosc: J Arthrosc Relat Surg Off Publ Arthrosc Assoc N AM Int Artrosc Assco 20(3):306–310

    Article  Google Scholar 

  • Feczko P, Hangody L et al (2003) Experimental results of donor site filling for autologous osteochondral mosaicplasty. Arthrosc: J Arthrosc Relat Surg Off Publ Arthrosc Assoc N AM Int Artrosc Assco 19(7):755–761

    Article  Google Scholar 

  • Garretson RB 3, Katolik LI et al (2004) Contact pressure at osteochondral donor sites in the patellofemoral joint. Am J Sports Med 32(4):967–974

    Article  PubMed  Google Scholar 

  • Gudas R, Kalesinskas RJ et al (2005) A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthrosc: J Arthrosc Relat Surg Off Publ Arthrosc Assoc N AM Int Artrosc Assoc 21(9):1066–1075

    Article  Google Scholar 

  • Hangody L, Fules P (2003) Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Joint Surg 85-A(Suppl 2):25–32

    PubMed  Google Scholar 

  • Hangody L, Vasarhelyi G et al (2008) Autologous osteochondral grafting – technique and long-term results. Injury 39(Suppl 1):S32–S39

    Article  PubMed  Google Scholar 

  • Harris JD, Brophy RH et al (2010) Treatment of chondral defects in the athlete’s knee. Arthrosc: J Arthrosc Relat Surg Off Publ Arthrosc Assoc N AM Int Artrosc Assoc 26(6):841–852

    Article  Google Scholar 

  • Huang FS, Simonian PT et al (2004) Effects of small incongruities in a sheep model of osteochondral autografting. Am J Sports Med 32(8):1842–1848

    Article  PubMed  Google Scholar 

  • Hurtig MB (1999) The effect of graft size and number on the outcome of mosaic arthroplasty resurfacing: an experimental model in sheep. Proc Arthrosc Assoc N Am

    Google Scholar 

  • Kock NB, Van Susante JL et al (2006) Press-fit stability of an osteochondral autograft: influence of different plug length and perfect depth alignment. Acta Orthop 77(3):422–428

    Article  PubMed  Google Scholar 

  • Koh JL, Wirsing K et al (2004) The effect of graft height mismatch on contact pressure following osteochondral grafting: a biomechanical study. Am J Sports Med 32(2):317–320

    Article  PubMed  Google Scholar 

  • Koh JL, Kowalski A et al (2006) The effect of angled osteochondral grafting on contact pressure: a biomechanical study. Am J Sports Med 34(1):116–119

    Article  PubMed  Google Scholar 

  • Kon E, Gobbi A et al (2009) Arthroscopic second-generation autologous chondrocyte implantation compared with microfracture for chondral lesions of the knee: prospective nonrandomized study at 5 years. Am J Sports Med 37(1):33–41

    Article  PubMed  Google Scholar 

  • Kordas G, Szabo JS et al (2006) Primary stability of osteochondral grafts used in mosaicplasty. Arthrosc J Arthrosc Relat Surg Off Publ Arthrosc Assoc N AM Int Artrosc Assoc 22(4):414–421

    Article  Google Scholar 

  • Krych AJ, Harnly HW et al (2012) Activity levels are higher after osteochondral autograft transfer mosaicplasty than after microfracture for articular cartilage defects of the knee: a retrospective comparative study. J Bone Joint Surg 94(11):971–978

    Article  PubMed  Google Scholar 

  • Lane JG, Massie JB et al (2004) Follow-up of osteochondral plug transfers in a goat model: a 6-month study. Am J Sports Med 32(6):1440–1450

    Article  PubMed  Google Scholar 

  • Lim HC, Bae JH et al (2012) Current treatments of isolated articular cartilage lesions of the knee achieve similar outcomes. Clin Orthop Relat Res 470(8):2261–2267

    Article  PubMed Central  PubMed  Google Scholar 

  • Marcacci M, Kon E et al (2007) Arthroscopic autologous osteochondral grafting for cartilage defects of the knee: prospective study results at a minimum 7-year follow-up. Am J Sports Med 35(12):2014–2021

    Article  PubMed  Google Scholar 

  • McCoy B, Miniaci A (2012) Osteochondral autograft transplantation/mosaicplasty. J Knee Surg 25(2):99–108

    Article  PubMed  Google Scholar 

  • Mithoefer K, Williams RJ, Mithoefer K, Williams RJ 3rd et al (2005) The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study. J Bone Joint Surg 87(9):1911–1920

    Article  PubMed  Google Scholar 

  • Pearce SG, Hurtig MB et al (2001) An investigation of 2 techniques for optimizing joint surface congruency using multiple cylindrical osteochondral autografts. Arthrosc J Arthrosc Relat Surg Off Publ Arthrosc Assoc N AM Int Artrosc Assoc 17(1):50–55

    Article  CAS  Google Scholar 

  • Solheim E, Hegna J et al (2010) Osteochondral autografting (mosaicplasty) in articular cartilage defects in the knee: results at 5 to 9 years. Knee 17(1):84–87

    Article  PubMed  Google Scholar 

  • Whiteside RA, Jakob RP et al (2005) Impact loading of articular cartilage during transplantation of osteochondral autograft. J Bone Joint Surg 87(9):1285–1291

    Article  CAS  Google Scholar 

  • Yamashita F, Sakakida K et al (1985) The transplantation of an autogeneic osteochondral fragment for osteochondritis dissecans of the knee. Clin Orthopaed Relat Res 201:43–50

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aravind Athiviraham .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Athiviraham, A., Kodali, P., Miniaci, A. (2013). Surgical Treatment of Osteochondral Defects of the Knee with Mosaicplasty Technique. In: Doral, M., Karlsson, J. (eds) Sports Injuries. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36801-1_150-4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-36801-1_150-4

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-36801-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics