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Intensity-Based Registration for Lung Motion Estimation

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4D Modeling and Estimation of Respiratory Motion for Radiation Therapy

Abstract

Image registration plays an important role within pulmonary image analysis. The task of registration is to find the spatial mapping that brings two images into alignment. Registration algorithms designed for matching 4D lung scans or two 3D scans acquired at different inflation levels can catch the temporal changes in position and shape of the region of interest. Accurate registration is critical to post-analysis of lung mechanics and motion estimation. In this chapter, we discuss lung-specific adaptations of intensity-based registration methods for 3D/4D lung images and review approaches for assessing registration accuracy. Then we introduce methods for estimating tissue motion and studying lung mechanics. Finally, we discuss methods for assessing and quantifying specific volume change, specific ventilation, strain/ stretch information and lobar sliding.

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Notes

  1. 1.

    However, we need to mention that this is not fully true due to the increased blood volume through inhalation [43].

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Cao, K. et al. (2013). Intensity-Based Registration for Lung Motion Estimation. In: Ehrhardt, J., Lorenz, C. (eds) 4D Modeling and Estimation of Respiratory Motion for Radiation Therapy. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36441-9_7

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