Abstract
The first significant histologic classification of tumors of the central nervous system (CNS) was proposed by Bailey and Cushing in 1926. Thereafter, several major revisions were introduced, and numerous consensus conferences were held. The grading of CNS tumors is an integral part of these revisions and is routinely applied to primary intracranial and spinal tumors. The most widely accepted grading system is the World Health Organization (WHO) classification of tumors, last updated in 2007. Recently the prognostic values of several genetic markers have been validated in several CNS tumors, and the importance of testing them in paraffin-embedded tissue is growing [1]. Rare tumors, lymphomas, paraganglioma, and pituitary adenomas will not be discussed in this concise chapter.
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© 2013 Springer-Verlag Berlin Heidelberg
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Ma, M.J. (2013). Tumors of the Central Nervous System. In: Damjanov, I., Fan, F. (eds) Cancer Grading Manual. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34516-6_15
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DOI: https://doi.org/10.1007/978-3-642-34516-6_15
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