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Properties of DNA

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Handbook of Nanomaterials Properties

Abstract

Deoxyribonucleic acid (DNA) is best known for its central role in the encoding, storage, replication, and propagation of genetic information within all known, independently living organisms. However, DNA is also a chemical material that can be produced in industrial quantities by well-developed, synthetic chemistry techniques for a wide variety of biological and nonbiological purposes. As a polymeric material with known nanometer-scale dimensions and well-understood, programmable, molecular recognition capabilities, DNA has become a leading construction material for bottom-up fabrication of nanomaterials with complex structures and functions. This field, known as structural DNA nanotechnology, has recently become a major source of self-assembling, molecularly programmed materials. To fully comprehend the design rules and application potential of DNA-based materials, it is critical for researchers to understand the characteristic properties of DNA itself; thus, delineating these underlying properties is the purpose of this chapter.

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Authors and Affiliations

  1. Duke University, Durham, NC, 27708, USA

    Ronnie Pedersen

  2. Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC, 27606, USA

    Jacob Majikes, Jessica A. Nash, Nicole A. Estrich, David S. Courson & Thomas H. LaBean

  3. Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA

    Alexandria N. Marchi

  4. Chemistry Department, Duke University, Durham, NC, 27708, USA

    Stephen L. Craig

  5. Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 27606, USA

    Carol K. Hall

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Editors and Affiliations

  1. Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics, Ohio State University, Columbus, Ohio, USA

    Bharat Bhushan

  2. Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York, USA

    Dan Luo

  3. Division of Restorative, Prosthetic and Primary Care, The Ohio State University, College of Dentistry, Columbus, Ohio, USA

    Scott R. Schricker

  4. Department of Materials Science and Engineering, University of Florida, Gainesville, Florida, USA

    Wolfgang Sigmund

  5. Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, USA

    Stefan Zauscher

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Pedersen, R. et al. (2014). Properties of DNA. In: Bhushan, B., Luo, D., Schricker, S., Sigmund, W., Zauscher, S. (eds) Handbook of Nanomaterials Properties. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31107-9_10

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