Abstract
Monitoring of brain tissue oxygenation represents one of an array of regional cerebral monitors including microdialysis for measurement of regional metabolism, thermal diffusion probes for measurements of CBF and near-infrared spectroscopy that also measures brain tissue oxygenation. Common for all modalities is that they comprise a supplement to the routinely used ICP monitoring. These regional monitors have gained increasing interest over the last two decades because they open up possibilities to develop treatment strategies aiming at optimizing not only ICP but also cerebral blood flow, oxygenation and metabolism.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bardt TF, Unterberg AW, Hartl R, Kiening KL, Schneider GH, Lanksch WR (1998) Monitoring of brain tissue PO2 in traumatic brain injury: effect of cerebral hypoxia on outcome. Acta Neurochir Suppl 71:153–156
Chang JJ, Youn TS, Benson D, Mattick H, Andrade N, Harper CR, Moore CB, Madden CJ, Diaz-Arrastia RR (2009) Physiologic and functional outcome correlates of brain tissue hypoxia in traumatic brain injury. Crit Care Med 37:283–290
Doppenberg EM, Zauner A, Watson JC, Bullock R (1998) Determination of the ischemic threshold for brain oxygen tension. Acta Neurochir Suppl 71:166–169
Figaji AA, Adelson PD (2009) Does ICP monitoring in children with severe head injuries make a difference? Am Surg 75:441–442
Figaji AA, Fieggen AG, Argent AC, Leroux PD, Peter JC (2008) Does adherence to treatment targets in children with severe traumatic brain injury avoid brain hypoxia? A brain tissue oxygenation study. Neurosurgery 63:83–91; discussion 91–92
Figaji AA, Zwane E, Thompson C, Fieggen AG, Argent AC, Le Roux PD, Peter JC (2009a) Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury. Part 1: relationship with outcome. Childs Nerv Syst 25:1325–1333
Figaji AA, Zwane E, Thompson C, Fieggen AG, Argent AC, Le Roux PD, Peter JC (2009b) Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury. Part 2: relationship with clinical, physiological, and treatment factors. Childs Nerv Syst 25:1335–1343
Fletcher JJ, Bergman K, Blostein PA, Kramer AH (2010) Fluid balance, complications, and brain tissue oxygen tension monitoring following severe traumatic brain injury. Neurocrit Care 13:47–56
Kiening KL, Unterberg AW, Bardt TF, Schneider GH, Lanksch WR (1996) Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation. J Neurosurg 85:751–757
Maloney-Wilensky E, Le Roux P (2010) The physiology behind direct brain oxygen monitors and practical aspects of their use. Childs Nerv Syst 26:419–430
Martini RP, Deem S, Yanez ND, Chesnut RM, Weiss NS, Daniel S, Souter M, Treggiari MM (2009) Management guided by brain tissue oxygen monitoring and outcome following severe traumatic brain injury. J Neurosurg 111:644–649
Meixensberger J, Dings J, Kuhnigk H, Roosen K (1993) Studies of tissue PO2 in normal and pathological human brain cortex. Acta Neurochir Suppl (Wien) 59:58–63
Meixensberger J, Jaeger M, Vath A, Dings J, Kunze E, Roosen K (2003) Brain tissue oxygen guided treatment supplementing ICP/CPP therapy after traumatic brain injury. J Neurol Neurosurg Psychiatry 74:760–764
Meixensberger J, Renner C, Simanowski R, Schmidtke A, Dings J, Roosen K (2004) Influence of cerebral oxygenation following severe head injury on neuropsychological testing. Neurol Res 26:414–417
Narotam PK, Morrison JF, Nathoo N (2009) Brain tissue oxygen monitoring in traumatic brain injury and major trauma: outcome analysis of a brain tissue oxygen-directed therapy. J Neurosurg 111:672–682
Pennings FA, Schuurman PR, van den Munckhof P, Bouma GJ (2008) Brain tissue oxygen pressure monitoring in awake patients during functional neurosurgery: the assessment of normal values. J Neurotrauma 25:1173–1177
Rosenthal G, Hemphill JC 3rd, Manley G (2009) Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med 37:379–380
Spiotta AM, Stiefel MF, Gracias VH, Garuffe AM, Kofke WA, Maloney-Wilensky E, Troxel AB, Levine JM, Le Roux PD (2010) Brain tissue oxygen-directed management and outcome in patients with severe traumatic brain injury. J Neurosurg 113(3):571–580
Stiefel MF, Heuer GG, Smith MJ, Bloom S, Maloney-Wilensky E, Gracias VH, Grady MS, LeRoux PD (2004) Cerebral oxygenation following decompressive hemicraniectomy for the treatment of refractory intracranial hypertension. J Neurosurg 101:241–247
Tolias CM, Reinert M, Seiler R, Gilman C, Scharf A, Bullock MR (2004) Normobaric hyperoxia–induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study. J Neurosurg 101:435–444
Valadka AB, Gopinath SP, Contant CF, Uzura M, Robertson CS (1998) Relationship of brain tissue PO2 to outcome after severe head injury. Crit Care Med 26:1576–1581
van den Brink WA, van Santbrink H, Steyerberg EW, Avezaat CJ, Suazo JA, Hogesteeger C, Jansen WJ, Kloos LM, Vermeulen J, Maas AI (2000) Brain oxygen tension in severe head injury. Neurosurgery 46:868–876; discussion 76–78
van Santbrink H, Maas AI, Avezaat CJ (1996) Continuous monitoring of partial pressure of brain tissue oxygen in patients with severe head injury. Neurosurgery 38:21–31
Zauner A, Doppenberg EM, Woodward JJ, Choi SC, Young HF, Bullock R (1997) Continuous monitoring of cerebral substrate delivery and clearance: initial experience in 24 patients with severe acute brain injuries. Neurosurgery 41:1082–1091; discussion 91–93
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Nielsen, T.H. (2012). Brain Tissue Oxygen Monitoring. In: Sundstrom, T., Grände, PO., Juul, N., Kock-Jensen, C., Romner, B., Wester, K. (eds) Management of Severe Traumatic Brain Injury. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28126-6_31
Download citation
DOI: https://doi.org/10.1007/978-3-642-28126-6_31
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-28125-9
Online ISBN: 978-3-642-28126-6
eBook Packages: MedicineMedicine (R0)