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Dry Skin in Diabetes Mellitus and in Experimental Models of Diabetes

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Textbook of Aging Skin

Abstract

Patients with diabetes often have dry scaly skin (Huntley AC, Dermatol Clin 7:531–46, 1989; Yosipovitch G, et al., Diabetes Care 21:506–9, 1998; Pavicic T, Korting HC, J Dtsch Dermatol Ges 4:935–41, 2006). Moreover, diabetes mellitus induces various forms of dermopathy such as bullosis diabeticorum, necrobiosis lipoidica diabeticorum, scleredema diabeticorum, and acanthosis nigricans (Jelinek J, Diabet Med 10:201–13, 1993). Nonhealing ulcers occur in approximately 15 % of patients with diabetes, and therefore, it is imperative to prevent ulcer formation and improve wound healing in these patients (Reiber GE, Diabet Med 13: S6-11, 1996; Margolis DJ, et al., Diabetes Care 25:1835–9, 2002). In general, diabetic atrophy is thought to result from complications such as vasculopathy and neuropathy. Insulin resistance and hyperglycemia contribute to the impaired physiologic function observed in various tissues of these patients.

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Author information

Authors and Affiliations

  1. Basic Research Laboratory, Kanebo Cosmetics Inc., 250-0002, Kanagawa, Japan

    Shingo Sakai

  2. Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan

    Hachiro Tagami

Authors
  1. Shingo Sakai
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  2. Hachiro Tagami
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Corresponding author

Correspondence to Shingo Sakai .

Editor information

Editors and Affiliations

  1. Procter & Gamble Co., Cincinnati, Ohio, USA

    Miranda A. Farage

  2. Procter & Gamble Co., Cincinnati, Ohio, USA

    Kenneth W. Miller

  3. Department Dermatology, University of California, San Francisco School of Medicine, San Francisco, California, USA

    Howard I. Maibach

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Sakai, S., Tagami, H. (2015). Dry Skin in Diabetes Mellitus and in Experimental Models of Diabetes. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27814-3_63-2

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  • DOI: https://doi.org/10.1007/978-3-642-27814-3_63-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27814-3

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