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Cellular Energy Metabolism and Oxidative Stress

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Textbook of Aging Skin

Abstract

The objective of this chapter is to provide an overview of how changes to the skin’s energy metabolism systems lead to a decline in function and hence contribute to skin aging. This chapter first discusses how the skin uses energy to maintain its appearance followed by a background on energy production in cells. Defects in energy production are part of the mitochondrial theory of aging, which will be introduced next. Skin-specific examples that support this theory of aging will be given as well as evidence that questions this theory. The examples are divided into chronological skin aging and extrinsic skin aging. Recent advances in understanding how environmental stresses, such as UV radiation, especially in the regions of ultraviolet-A (UVA), visible and near infrared (NIR), contribute to skin aging will be discussed. Lastly, examples of antiaging therapies that improve or maintain metabolic functions of the skin are given.

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Author information

Authors and Affiliations

  1. Colgate-Palmolive Company, 909 River Road, Piscataway, NJ, 8854, USA

    Shujiang (Suzie) Cheng, Regina Hourigan, Zeenat Nabi & Laurence Du-Thumm

Authors
  1. Shujiang (Suzie) Cheng
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  2. Regina Hourigan
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  3. Zeenat Nabi
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  4. Laurence Du-Thumm
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Corresponding author

Correspondence to Regina Hourigan .

Editor information

Editors and Affiliations

  1. Procter & Gamble Co., Cincinnati, Ohio, USA

    Miranda A. Farage

  2. Procter & Gamble Co., Cincinnati, Ohio, USA

    Kenneth W. Miller

  3. Department Dermatology, University of California, San Francisco School of Medicine, San Francisco, California, USA

    Howard I. Maibach

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Cheng, S.(., Hourigan, R., Nabi, Z., Du-Thumm, L. (2015). Cellular Energy Metabolism and Oxidative Stress. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27814-3_30-2

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  • DOI: https://doi.org/10.1007/978-3-642-27814-3_30-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27814-3

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