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Benign Tumors and Tumorous Conditions of Bone

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Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases

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Abstract

Benign tumors originating from bone, cartilage, fibrous tissue, vessels, and unknown tissues are one of the most interesting objectives of pinhole scintigraphy. Such tumors include osteoma, osteoid osteoma, osteoblastoma, chondroma, enostosis, chondroblastoma, fibrous cortical defect and nonossifying fibroma, osteochondroma, primary bone cysts, giant cell tumor, and others . Another large group of bone diseases, in the diagnosis of which 99mTcMDP scanning is beneficial, are tumorous conditions.

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References


  • Abdel-Dayem HM, Papademetriou T (1981) Subperiosteal hemorrhage in neurofibromatosis: appearance in scintigraphy. Clin Nucl Med 6:272


    Article  PubMed  Google Scholar 

  • Azous EM, Saigal G, Rodriguez MM, et al (2005) Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol 35:103–115


    Article  Google Scholar 

  • Baek JH, Lee SY, Kim SH, et al (1997) Pinhole bone scintigraphic manifestation of fibrous dysplasia. Korean J Nucl Med 31:452–458


    Google Scholar 

  • Bahk YW (1964) Dyschondroplasia with hemangiomata (Maffucci’s syndrome). Radiology 82:407–410


    PubMed  CAS  Google Scholar 

  • Bahk YW, Park YH, Chung SK, Chi JG (1995) Bone pathological correlation of multimodality imaging in Paget’s disease. J Nucl Med 36:1421–1426


    PubMed  CAS  Google Scholar 

  • Becelli R, Carboni A, Gianni C, Alterio A, Renzi G (2002) A rare condition of Hand-Schuller-Christian disease. J Craniofac Surg 13:759–761


    Article  PubMed  Google Scholar 

  • Benli IT, Akalin S, Boysan E, et al (1992) Epidemiological, clinical and radiological aspects of osteopoikilosis. J Bone Joint Surg Br 74:504–506


    PubMed  CAS  Google Scholar 

  • Black B, Dooley J, Pyper A, Reed M (1993) Multiple hereditary exostoses. An epidemiologic study of an isolated community in Manitoba. Clin Orthop Relat Res 287:212–217


    PubMed  Google Scholar 

  • Büll U, Keyl W, Meister P, et al (1981) Wertigkeit der ‚Region-of-interest’-Technik in der skelettszintigraphischen Diagnostik primärer Knochentumoren. Radiologe 21:46–51


    PubMed  Google Scholar 

  • Conklin JJ, Camargo EE, Wagner H Jr (1981) Bone scan detection of peripheral periosteal leiomyoma. J Nucl Med 22:97


    Google Scholar 

  • Crawford AH Jr, Bagamery N (1986) Osseous manifestations of neurofibromatosis in childhood. J Pediatr Orthop 6:72–88


    Article  PubMed  Google Scholar 

  • Crone-Munzebrock W, Brassow F (1983) A comparison of radiographic and bone scan findings in histiocytosis X. Skeletal Radiol 9:170–173


    Article  PubMed  CAS  Google Scholar 

  • D’Ambrosia R, Ferguson AB Jr (1968) The formation of osteochondroma by epiphyseal cartilage transplantation. Clin Orthop Relat Res 61:103–115


    PubMed  Google Scholar 

  • Dahlin DC, Unni KK (eds) (1986a) Osteoid osteoma. In: Bone tumors. 4th edn. Thomas, Springfield


    Google Scholar 

  • Dahlin DC, Unni KK (eds) (1986b) Chondroma. In: Bone tumors, 4th edn. Thomas, Springfield


    Google Scholar 

  • Davila JA, Amrami KK, Sundaram M, et al (2004) Chondroblastoma of the hands and feet. Skeletal Radiol 33:582–587


    Article  PubMed  Google Scholar 

  • Doyle T, Gunn J, Anderson G, et al (2002) Paget’s disease in New Zealand: evidence for declining prevalence. Bone 31:616–619


    Article  PubMed  CAS  Google Scholar 

  • Dupree WB, Enzinger FM (1986) Fibro-osseous pseudo-tumor of the digits. Cancer 58:2103–2109


    Article  PubMed  CAS  Google Scholar 

  • Epstein DA, Levin EJ (1978) Bone scintigraphy in hereditary multiple exostoses. AJR Am J Roentgenol 130:331–333


    PubMed  CAS  Google Scholar 

  • Fitzer PM (1977) Radionuclide angiography – brain and bone imaging in craniofacial dysplasia (CFD): case report. J Nucl Med 18:709–712


    PubMed  CAS  Google Scholar 

  • Ferracini R, Zorzan A, Mauro PP, Masse G, Masterson EL (1998) Acetabular osteoblastoma: description of a case. Chir Organi Mov 83:413–417


    PubMed  CAS  Google Scholar 

  • Focacci C, Lattanzi R, Iadeluca ML, Campioni P (1998) Nuclear medicine in primary bone tumors. Eur J Radiol 27 [Suppl 1]:S123–131


    Article  PubMed  Google Scholar 

  • Garrison RC, Unni KK, MeLeod RA, et al (1982) Chondrosarcoma arising in osteochondroma. Cancer 49:1890–1897


    Article  PubMed  CAS  Google Scholar 

  • Greenspan A (1995) Bone island (enostosis): current concept – a review. Skeletal Radiol 24:111–115


    PubMed  CAS  Google Scholar 

  • Hall FM, Goldberg RP, Davies JAK, et al (1980) Scintigraphic assessment of bone islands. Radiology 135:737–742


    PubMed  CAS  Google Scholar 

  • Helms CA, Hattner RS, Vogler JB III (1984) Radionuclide skeletal survey for pediatric neoplasms. Radiology 151:779–785


    PubMed  CAS  Google Scholar 

  • Hudson TM (1984) Scintigraphy of aneurysmal bone cysts. AJR Am J Roentgenol 142:761–765


    PubMed  CAS  Google Scholar 

  • Humphry A, Gilday DL, Brown RG (1980) Bone scintigraphy in chondroblastoma. Radiology 137:497–499


    PubMed  CAS  Google Scholar 

  • Jaffe HL (ed) (1958a) Fibrous cortical defect and non-ossifying fibroma. In: Tumors and tumorous conditions of the bones and joints. Lea & Febiger, Philadelphia, pp 76–91


    Google Scholar 

  • Jaffe HL (ed) (1958b) Solitary bone cyst. In: Tumors and tumorous conditions of the bones and joints. Lea & Febiger, Philadelphia, pp 63–75


    Google Scholar 

  • Jee WH, Park YK, McCauley TR, et al (1999) Chondroblastoma: MR characteristics with pathologic correlation. J Comput Tomogr 23:721–726


    Article  CAS  Google Scholar 

  • Kaim AH, Hugli R, Bonel HM, Jundt G (2002) Chondroblastoma and clear cell chondrosarcoma: radiological and MRI characteristics with histopathological correlation. Skeletal Radiol 31:88–95


    Article  PubMed  Google Scholar 

  • Keith A (1920) Studies on the anatomical changes which accompany certain growth disorders of the human body. I. The nature of the structural alterations in the disorder known as multiple exostosis. J Anat 54:101–115


    PubMed  CAS  Google Scholar 

  • Kim JY, Chung SK, Park YH, et al (1992) Pinhole bone scintigraphic appearances of osteoid osteoma. Korean J Nucl Med 26:160–163


    Google Scholar 

  • Levine E, De Smet AA, Neff JR, et al (1984) Scintigraphic evaluation of giant cell tumor of bone. AJR Am J Roentgenol 143:343–348


    PubMed  CAS  Google Scholar 

  • Lichtenstein L (1972) Osteocartilaginous exostosis In: Bone tumors, 4rh edn. Mosby, Saint Louis, pp 17–28


    Google Scholar 

  • Lisbona R, Rosenthall L (1979) Role of radionuclide imaging in osteoid osteoma. AJR Am J Roentgenol 132:77–80


    PubMed  CAS  Google Scholar 

  • McLeod RA,Beabout JW (1973) The roentgenographic features of chondroblastoma. AJR Am J Roentgenol 118:646–471


    Google Scholar 

  • Mirra JM (1989a) Fibrohistiocytic tumors of intramedullary origin. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 692–719


    Google Scholar 

  • Mirra JM (1989b) Aneurysmal bone cyst. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 1267–1331


    Google Scholar 

  • Mirra JM (1989c) Eosinophilic granuloma. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 1023–1045


    Google Scholar 

  • Mirra JM (1989d) Giant cell tumors. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, p 958 (Fig. 13.17)


    Google Scholar 

  • Mirra JM (1989e) Periostitis ossificans. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 1589–1605


    Google Scholar 

  • Mirra JM, Eckhardt JJ (1989) Enchondroma versus chondrosarcoma. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 476–531


    Google Scholar 

  • Mirra JM, Gold RH (1989) Fibrous dysplasia. In: Mirra JM (ed) Bone tumors. Lea & Febiger, Philadelphia, pp 191–226


    Google Scholar 

  • Mungovan JA, Tung GA, Lambiase RE, et al (1994) Tc-99 m MDP uptake in osteopoikilosis. Clin Nucl Med 19:6–8


    Article  PubMed  CAS  Google Scholar 

  • Nadel HT, Rossleigh MA (1995) Tumor imaging. In: Treves ST (ed) Pediatric nuclear medicine, 2nd edn. Springer, Berlin Heidelberg New York, pp 496–527


    Google Scholar 

  • Neumann RD, Kemp JD, Weiner RE (1995) Gallium-67 imaging for detection of malignant disease. In: Sandler MP, et al (eds) Diagnostic nuclear medicine, 3rd edn. Williams and Wilkins, Baltimore, pp 1243–1260


    Google Scholar 

  • Nishio J, Iwasaki H, Soejima O, et al (2002) Rapidly growing fibro-osseous pseudotumor of the digits mimicking extraskeletal osteosarcoma. J Orthop Sci 7:410–413


    Article  PubMed  Google Scholar 

  • Ochsner PE (1978) Multiple cartilaginous exostoses and neoplastic degeneration: review of the literature. Z Orthop Ihre Grenzgeb 116:369–378


    PubMed  CAS  Google Scholar 

  • O’Connell JX, Nanthakumar SS; Nielsen GP, Rosenberg AE (1998) Osteoid osteoma: the uniquely innervated bone tumor. Mod Pathol 11:175–180


    PubMed  Google Scholar 

  • Parker BR, Pinckney L, Etcubanas E (1980) Relative efficacy of radiographic and radionuclide bone surveys in the detection of the skeletal lesions of histiocytosis X. Radiology 134:377–380


    PubMed  CAS  Google Scholar 

  • Patel MR, Desai SS (1986) Pseudomalignant osseous tumor of soft tissue: a case report and review of the literature. J Hand Surg [Am] 11:66–70


    CAS  Google Scholar 

  • Pierz KA, Stieber JR, Kusumi K, Dromans JP (2002) Hereditary multiple exostoses: one center’s experience and review of etiology. Clin Orthop Relat Res 401:49–59


    Article  PubMed  Google Scholar 

  • Pinkas L, Robinson D, Halpern N, et al (2001) 99mTc-MIBI scintigraphy in musculoskeletal tumors. J Nucl Med 42:33–37


    PubMed  CAS  Google Scholar 

  • Rambeloarisoa J, el Guedj M, Legeai-Mallet L, et al (2002) Hereditary multiple exostoses after 40 years of development: a case report. Rev Med Interne 23:657–664


    Article  PubMed  CAS  Google Scholar 

  • Resnick D, Niwayama G (1988) Enostosis, hyperostosis, and periostitis. In: Resnick D, Niwayama G (eds) Diagnosis of bone and joint disorders, 2nd ed. Saunders, Philadelphia, pp 4073–4139


    Google Scholar 

  • Revel PA (1986) Paget’s disease of bone. In: Pathology of bone. Springer, Berlin Heidelberg New York, pp 147–167


    Chapter  Google Scholar 

  • Roodman GD, Windle JJ (2005) Paget disease of bone. J Clin Invest 115:200–208


    PubMed  CAS  Google Scholar 

  • Schaub T, Hahn K (1990) Fibröse Dysplasie. In: Brussatis F, Hahn K (eds) Nuklearmedizin in der Orthopädie. Springer, Berlin Heidelberg New York


    Google Scholar 

  • Serafini AN (1976) Paget’s disease of the bone. Semin Nucl Med 6:47–58


    Article  PubMed  CAS  Google Scholar 

  • Shi YR, Wu JY, Hsu YA, et al (2002) Mutation screening of the EXT genes in patients with hereditary multiple exostoses in Taiwan. Genet Test 6:237–243


    Article  PubMed  CAS  Google Scholar 

  • Sim FH, Dahlin DC, Beabout JW (1975) Osteoid osteoma: diagnostic problems. J Bone Joint Surg Am 63:154–159


    Google Scholar 

  • Van Nostrand D, Madewell JE, NcNiesh LM, et al (1986) Radionuclide bone scanning in giant cell tumor. J Nucl Med 27:329–338


    PubMed  Google Scholar 

  • Waxman AD (1995) Thallium-201 and technetium-99 m methoxyisobutyl isonitrile in nuclear oncology. In: Sandler MP, et al (eds) Diagnostic nuclear medicine, 3rd edn. Williams and Wilkins, Baltimore, pp 1261–1274


    Google Scholar 

  • Westra SJ, van Woerden H, Postma A, et al (1983) Radio-nuclide bone scintigraphy in patients with histiocytosis X. Eur J Nucl Med 8:303–306


    Article  PubMed  CAS  Google Scholar 

  • Whyte MP, Murphy WA, Siegel BA (1978) 99mTc-pyrophosphate bone imaging in osteopoikilosis, osteopathia astriata, and melorheostosis. Radiology 127:439–443


    PubMed  CAS  Google Scholar 

  • Woldenberg Y, Nash M, Bodner L (2005) Peripheral osteoma of the maxillofacial region. Diagnosis and management: a study of 14 cases. Med Oral Patol Oral Cir Bucal 10 [Suppl 2]:E139–142

    PubMed  Google Scholar 

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  1. Yong-Whee Bahk

    Present address: Depart. of Nuclear Med. and Radiology, Sun Ae General Hospital, Seoul, Korea, Republic of

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    Bahk, YW. (2013). Benign Tumors and Tumorous Conditions of Bone. In: Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25144-3_18

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    • DOI: https://doi.org/10.1007/978-3-642-25144-3_18

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