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Surgical Management of Aerodigestive Tract Invasion in Thyroid Cancer

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Surgery of the Thyroid and Parathyroid Glands

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Abstract

Locally advanced thyroid cancer, originating from the central neck in close proximity to the tracheal and esophageal walls, has a natural tendency to invade the aerodigestive tract. To reflect the fact that tracheal and esophageal involvement has prognostic ramifications, a separate UICC/AJCC tumor category has been devised, placing thyroid cancers with aerodigestive tract involvement in an intermediate position (T4a) above cancers with extrathyroidal spread limited to the thyroid capsule (T3b) and below cancers invading the prevertebral space posteriorly, the mediastinum inferiorly, or the carotid artery laterally (T4b). Because extrathyroidal invasion is associated with both locoregional tumor recurrence and distant metastases, it accounts for approximately one-third of thyroid cancer-specific mortality.

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References

  1. Ashford BG, Clark JR (2009) Cricotracheal reconstruction following external beam radiotherapy for recurrent thyroid cancer. ANZ J Surg 79:271–274

    Article  PubMed  Google Scholar 

  2. Bayles SW, Kingdom TT, Carlson GW (1998) Management of thyroid carcinoma invading the aerodigestive tract. Laryngoscope 108:1402–1407

    Article  PubMed  CAS  Google Scholar 

  3. Brauckhoff M, Meinicke A, Bilkenroth U, Lorenz K, Brauckhoff K, Gimm O, Nguyen Thanh P, Dralle H (2006) Long-term results and functional outcome after cervical evisceration in patients with thyroid cancer. Surgery 140:953–959

    Article  PubMed  Google Scholar 

  4. Brauckhoff M, Machens A, Nguyen Thanh P, Lorenz K, Schmeil A, Stratmann M, Sekulla C, Brauckhoff K, Dralle H (2010) Impact of extent of resection for thyroid cancer invading the aerodigestive tract on surgical morbidity, local recurrence and cancer-specific survival. Surgery 148(6):1257–1266

    Article  PubMed  Google Scholar 

  5. Czaja JM, McCaffrey TV (1997) The surgical management of laryngotracheal invasion by well-differentiated papillary thyroid carcinoma. Arch Otolaryngol Head Neck Surg 123:484–490

    Article  PubMed  CAS  Google Scholar 

  6. Dralle H, Scheumann GF, Meyer HJ, Laubert A, Pichlmayr R (1992) Cervical interventions on the airway and esophagus in infiltrating thyroid cancer. Chirurg 63:282–290

    PubMed  CAS  Google Scholar 

  7. Dralle H, Brauckhoff M, Machens A (2005) Surgical management of advanced thyroid cancer invading the aerodigestive tract. In: Clark OH, Duh QY, Kebebew E (eds) Textbook of endocrine surgery. Elsevier, Philadelphia, pp 318–333

    Chapter  Google Scholar 

  8. Friedman M (1990) Surgical management of thyroid carcinoma with laryngotracheal invasion. Otolaryngol Clin North Am 23:495–507

    PubMed  CAS  Google Scholar 

  9. Gaissert HA, Honings J, Grillo HC, Donahue DM, Wain JC, Wright CD, Mathisen DJ (2007) Segmental laryngotracheal and tracheal resection for invasive thyroid carcinoma. Ann Thorac Surg 83:1952–1959

    Article  PubMed  Google Scholar 

  10. Gillenwater AM, Goepfert H (1999) Surgical management of laryngotracheal and esophageal involvement by locally advanced thyroid cancer. Semin Surg Oncol 16:19–29

    Article  PubMed  CAS  Google Scholar 

  11. Grillo HC, Zannini P (1986) Resection management of airway invasion by thyroid carcinoma. Ann Thorac Surg 42:287–298

    Article  PubMed  CAS  Google Scholar 

  12. Grillo HC, Suen HC, Mathisen DJ, Wain JC (1992) Resectional management of thyroid carcinoma invading the airway. Ann Thorac Surg 54:3–9

    Article  PubMed  CAS  Google Scholar 

  13. Grillo HC (2002) Tracheal replacement: a critical review. Ann Thorac Surg 73:1995–2004

    Article  PubMed  Google Scholar 

  14. Grillo HC (2004) Tracheal reconstruction: anterior approach and extended resection. In: Grillo HC (ed) Surgery of the trachea and bronchi. BC Decker Inc, Lewiston, pp 517–547

    Google Scholar 

  15. Heitmiller RF (1996) Tracheal release maneuvers. Chest Surg Clin N Am 6:675–682

    PubMed  CAS  Google Scholar 

  16. Kitamura Y, Shimizu K, Nagahama M, Sugino K, Ozaki O, Mimura T, Ito K, Ito K, Tanaka S (1999) Immediate causes of death in thyroid carcinoma: clinicopathological analysis of 161 fatal cases. J Clin Endocrinol Metab 84:4043–4049

    Article  PubMed  CAS  Google Scholar 

  17. Koike E, Yamashita H, Noguchi S, Yamashita H, Ohshima A, Watanabe S, Uchino S, Takatsu K, Nishii R (2001) Bronchoscopic diagnosis of thyroid cancer with laryngotracheal invasion. Arch Surg 136:1185–1189

    Article  PubMed  CAS  Google Scholar 

  18. Lanuti M, Mathisen DJ (2003) Management of complications of tracheal surgery. Chest Surg Clin N Am 13:385–397

    Article  PubMed  Google Scholar 

  19. Machens A, Hinze R, Dralle H (2001) Surgery on the cervicovisceral axis for invasive thyroid cancer. Langenbecks Arch Surg 386:318–323

    Article  PubMed  CAS  Google Scholar 

  20. Machens A, Hinze R, Lautenschläger C, Thomusch O, Dralle H (2001) Thyroid carcinoma invading the cervicovisceral axis: routes of invasion and clinical implications. Surgery 129:23–28

    Article  PubMed  CAS  Google Scholar 

  21. Machens A, Hauptmann S, Dralle H (2008) Referral bias in thyroid cancer surgery: direction and magnitude. Eur J Surg Oncol 34:556–562

    Article  PubMed  CAS  Google Scholar 

  22. Maeda M, Nakamoto K, Ohta M, Nakamura K, Nanjo S, Taniguchi K, Tsubota N (1989) Statistical survey of tracheobronchoplasty in Japan. J Thorac Cardiovasc Surg 97:402–414

    PubMed  CAS  Google Scholar 

  23. Nakao K, Kurozumi K, Fukushima S, Nakahara M, Tsujimoto M, Nishida T (2001) Merits and demerits of operative procedure to the trachea in patients with differentiated thyroid cancer. World J Surg 25:723–727

    Article  PubMed  CAS  Google Scholar 

  24. Nakao K, Kurozumi K, Nakahara M, Kido T (2004) Resection and reconstruction of the airway in patients with advanced thyroid cancer. World J Surg 28:1204–1206

    Article  PubMed  Google Scholar 

  25. Nishida T, Nakao K, Hamaji M (1997) Differentiated thyroid carcinoma with airway invasion: indication for tracheal resection based on the extent of cancer invasion. J Thorac Cardiovasc Surg 114:84–92

    Article  PubMed  CAS  Google Scholar 

  26. Nomori H, Kobayashi K, Ishhara T, Torikata C, Hosada Y, Ozaki O, Ito K (1990) Thyroid carcinoma infiltrating the trachea: clinical, histologic and morphometric analysis. J Surg Oncol 44:78–83

    Article  PubMed  CAS  Google Scholar 

  27. Rubin Ph, Hansen JT (2008) TNM staging atlas. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  28. Sobin LH, Gospodarowicz MK, Wittekind Ch (eds) (2009) TNM classification of malignant tumors, 7th edn. Wiley, Hoboken

    Google Scholar 

  29. Tsukahara K, Sugitani I, Kawabata K (2009) Surgical management of tracheal shaving for papillary thyroid carcinoma with tracheal invasion. Acta Otolaryngol 129:1498–1502

    Article  PubMed  Google Scholar 

  30. Tsumori T, Nakao K, Miyata M, Izukura M, Monden Y, Sakurai M, Kawashima Y, Nakahara K (1985) Clinicopathologic study of thyroid carcinoma infiltrating the trachea. Cancer 56:2843–2848

    Article  PubMed  CAS  Google Scholar 

  31. Wada N, Nakayama H, Masudo Y, Suganuma N, Rino Y (2006) Clinical outcome of different modes of resection in papillary thyroid carcinomas with laryngotracheal invasion. Langenbecks Arch Surg 391:545–549

    Article  PubMed  Google Scholar 

  32. Wright CD, Grillo HC, Wain JC, Wong DR, Donahue DM, Gaissert HA, Mathisen DJ (2004) Anastomotic complications after tracheal resection: prognostic factors and management. J Thorac Cardiovasc Surg 128:731–739

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of General, Visceral and Vascular Surgery, Medical Faculty, University of Halle-Wittenberg, Ernst-Grube-Str. 40, D-06097, Halle/Saale, Germany

    Henning Dralle M.D. & Andreas Machens M.D.

  2. Department of Surgery, Haukeland University Hospital, Bergen, Norway

    Michael Brauckhoff M.D.

Authors
  1. Henning Dralle M.D.
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  2. Andreas Machens M.D.
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  3. Michael Brauckhoff M.D.
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Correspondence to Henning Dralle M.D. .

Editor information

Editors and Affiliations

  1. Chairman, Department of Surgery, University Hospital Basel, Spitalstr. 21, Basel, 4031, Switzerland

    Daniel Oertli

  2. Yale-New Haven Hospital, Department of Surgery, Yale University School of Medicine, Cedar Street 330FMB 102, New Haven, CT, 06520-8062, USA

    Robert Udelsman

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Dralle, H., Machens, A., Brauckhoff, M. (2012). Surgical Management of Aerodigestive Tract Invasion in Thyroid Cancer. In: Oertli, D., Udelsman, R. (eds) Surgery of the Thyroid and Parathyroid Glands. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23459-0_25

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  • DOI: https://doi.org/10.1007/978-3-642-23459-0_25

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-23458-3

  • Online ISBN: 978-3-642-23459-0

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