Skip to main content

High-Frequency Oscillatory Ventilation in the Neonate

  • Chapter
  • First Online:
Pediatric and Neonatal Mechanical Ventilation

Abstract

The classical approach was to consider to switch the patient to HFOV when conventional modes of ventilation fail to provide adequate oxygenation or adequate alveolar ventilation (i.e. rescue HFOV) in infants with respiratory distress syndrome given the more recent understanding that “non-lung-protective” mechanical ventilation, large tidal volume ventilation and/or high peak pressure ventilation or probably more high peak to PEEP pressure swings can cause or worsen lung injury in the experimental setting within a short time period Therefore, to initiate in (prematurely born) newborns HFOV early (i.e. from birth and/or immediately after intubation) as a lung-protective ventilator sounds reasonable The second concept to be applied is to search for adequate lung recruitment. In addition choosing oscillation frequency and amplitude optimal according respiratory system mechanics seems to be of importance. Part of these concepts of optimizing HFOV settings at bedside do also apply to the use of HFOV in bigger children. In this chapter we try to give some “recipes” for optimizing the use of HFOV in various clinical conditions and age categories.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Allen JL, Fredberg JJ, Keefe DH et al (1985) Alveolar pressure magnitude and asynchrony during high-frequency oscillations of excised rabbit lungs. Am Rev Respir Dis 132(2):343–349

    CAS  PubMed  Google Scholar 

  • Allen JL, Frantz ID 3rd, Fredberg JJ (1987) Heterogeneity of mean alveolar pressure during high-frequency oscillations. J Appl Physiol 62(1):223–228

    CAS  PubMed  Google Scholar 

  • Bhuta T, Clark RH, Henderson-Smart DJ (2001) Rescue high frequency oscillatory ventilation vs conventional ventilation for infants with severe pulmonary dysfunction born at or near term (Cochrane Review). Cochrane Database Syst Rev (1):CD002974

    Google Scholar 

  • Bjorklund LJ, Ingimarsson J, Curstedt T et al (1997) Manual ventilation with a few large breaths at birth compromises the therapeutic effect of subsequent surfactant replacement in immature lambs. Pediatr Res 42(3):348–355

    Article  CAS  PubMed  Google Scholar 

  • Blumenthal I (2004) Periventricular leucomalacia: a review. Eur J Pediatr 163:435–442

    Article  PubMed  Google Scholar 

  • Boynton BR, Hammond MD, Fredberg JJ et al (1989) Gas exchange in healthy rabbits during high-frequency oscillatory ventilation. J Appl Physiol 66:1343–51

    CAS  PubMed  Google Scholar 

  • Brazelton TB 3rd, Watson KF, Murphy M et al (2001) Identification of optimal lung volume during high-frequency oscillatory ventilation using respiratory inductive plethysmography. Crit Care Med 29(12):2349–2359

    Article  PubMed  Google Scholar 

  • Bryan AC, Cox PN (1999) History of high frequency oscillation. Schweiz Med Wochenschr 129(43):1613–1616

    CAS  PubMed  Google Scholar 

  • Clark R, Gerstmann D, Null D et al (1986) Pulmonary interstitial emphysema treated by high-frequency oscillatory ventilation. Crit Care Med 14:926–930

    Article  CAS  PubMed  Google Scholar 

  • Clark RH, Yoder BA, Sell MS (1994) Prospective, randomized comparison of high-frequency oscillation and conventional ventilation in candidates for extracorporeal membrane oxygenation. J Pediatr 124(3):447–454

    Article  CAS  PubMed  Google Scholar 

  • Cools F, Askie LM, Offringa M et al (2010) Elective high-frequency oscillatory versus conventional ventilation in preterm infants: a systematic review and meta-analysis of individual patients' data. Lancet 375(9731):2082–2091

    Article  PubMed  Google Scholar 

  • Courtney SE, Durand DJ, Asselin JM et al (2002) High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants. N Engl J Med 347(9):643–652

    Article  PubMed  Google Scholar 

  • De Jaegere A, van Veenendaal MB, Michiels A, van Kaam AH (2006) Lung recruitment using oxygenation during open lung high-frequency ventilation in preterm infants. Am J Respir Crit Care Med 174(6):639–645

    Article  PubMed  Google Scholar 

  • Dreyfuss D, Basset G, Soler P, Saumon G (1985) Intermittent positive-pressure hyperventilation with high inflation pressures produces pulmonary microvascular injury in rats. Am Rev Respir Dis 132:880–884

    CAS  PubMed  Google Scholar 

  • Fessler HE, Derdak S, Ferguson ND et al (2007) A protocol for high-frequency oscillatory ventilation in adults: results from a roundtable discussion. Crit Care Med 35(7):1649–1654

    Article  PubMed  Google Scholar 

  • Gerstmann DR, Fouke JM, Winter DC et al (1990) Proximal, tracheal, and alveolar pressures during high-frequency oscillatory ventilation in a normal rabbit model. Pediatr Res 28(4):367–373

    Article  CAS  PubMed  Google Scholar 

  • Giannakopoulou C, Korakaki E, Manoura A et al (2004) Significance of hypocarbia in the development of periventricular leukomalacia in preterm infants. Pediatr Int 46:268–273

    Article  PubMed  Google Scholar 

  • Hachey WE, Eyal FG, Curtet-Eyal NL, Kellum FE (1998) High-frequency oscillatory ventilation versus conventional ventilation in a piglet model of early meconium aspiration. Crit Care Med 26(3):556–561

    Article  CAS  PubMed  Google Scholar 

  • Hager DN, Fessler HE, Kaczka DW et al (2007) Tidal volume delivery during high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome. Crit Care Med 35(6):1522–1529

    Article  PubMed  Google Scholar 

  • Henderson-Smart DJ, Cools F, Bhuta T, Offringa M (2007) Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev (3):CD000104

    Google Scholar 

  • Ito Y, Veldhuizen RA, Yao LJ, McCaig LA, Bartlett AJ, Lewis JF (1997) Ventilation strategies affect surfactant aggregate conversion in acute lung injury. Am J Respir Crit Care Med 155(2):493–499

    Article  CAS  PubMed  Google Scholar 

  • Kamitsuka MD, Boynton BR, Villanueva D et al (1990) Frequency, tidal volume, and mean airway pressure combinations that provide adequate gas exchange and low alveolar pressure during high frequency oscillatory ventilation in rabbits. Pediatr Res 27:64–9

    Article  CAS  PubMed  Google Scholar 

  • Nobuhara KK, Lund DP, Mitchell J, Kharasch V, Wilson JM (1996) Long-term outlook for survivors of congenital diaphragmatic hernia. Clin Perinatol 23(4):873–887

    CAS  PubMed  Google Scholar 

  • Pellicano A, Tingay DG, Mills JF, Fasulakis S, Morley CJ, Dargaville PA (2009) Comparison of four methods of lung volume recruitment during high frequency oscillatory ventilation. Intensive Care Med 35(11):1990–1998

    Article  PubMed  Google Scholar 

  • Pillow JJ (2005) High-frequency oscillatory ventilation: mechanisms of gas exchange and lung mechanics. Crit Care Med 33(3 Suppl):S135–S141

    Article  PubMed  Google Scholar 

  • Randomized study of high-frequency oscillatory ventilation in infants with severe respiratory distress syndrome. HiFO Study Group (1993) J Pediatr 122(4):609–619

    Google Scholar 

  • Richard JC, Maggiore SM, Jonson B, Mancebo J, Lemaire F, Brochard L (2001) Influence of tidal volume on alveolar recruitment. Respective role of PEEP and a recruitment maneuver. Am J Respir Crit Care Med 163(7):1609–1613

    Article  CAS  PubMed  Google Scholar 

  • Rimensberger PC, Beghetti M, Hanquinet S, Berner M (2000) First intention high-frequency oscillation with early lung volume optimization improves pulmonary outcome in very low birth weight infants with respiratory distress syndrome. Pediatrics 105(6):1202–1208

    Article  CAS  PubMed  Google Scholar 

  • Sedeek KA, Takeuchi M, Suchodolski K et al (2003) Determinants of tidal volume during high-frequency oscillation. Crit Care Med 31(1):227–231

    Article  PubMed  Google Scholar 

  • Sturtz WJ, Touch SM, Locke RG et al (2008) Assessment of neonatal ventilation during high-frequency oscillatory ventilation. Pediatr Crit Care Med 9(1):101–104

    Article  PubMed  Google Scholar 

  • The Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342(18):1301–1308

    Google Scholar 

  • Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS (1997) Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 99(5):944–952

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Van de Kieft M, Dorsey D, Morison D et al (2005) High-frequency oscillatory ventilation: lessons learned from mechanical test lung models. Crit Care Med 33(3 Suppl):S142–S147

    Article  PubMed  Google Scholar 

  • van Heerde M, van Genderingen HR, Leenhoven T, Roubik K, Plötz FB, Markhorst DG (2006) Imposed work of breathing during high-frequency oscillatory ventilation: a bench study. Crit Care 10(1):R23

    Article  PubMed Central  PubMed  Google Scholar 

  • van Velzen A, De Jaegere A, van der Lee J, van Kaam A (2009) Feasibility of weaning and direct extubation from open lung high-frequency ventilation in preterm infants. Pediatr Crit Care Med 10(1):71–75

    Article  PubMed  Google Scholar 

  • Venegas JG, Fredberg JJ (1994) Understanding the pressure cost of ventilation: why does high-frequency ventilation work? Crit Care Med 22:S49–S57

    Article  CAS  PubMed  Google Scholar 

  • Yeh T (2010) Core Concepts: Meconium Aspiration Syndrome: Pathogenesis and Current Management. Neoreviews 11:e503–e512

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Peter C. Rimensberger or Gerhard K. Wolf MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Arnold, J.H., Rimensberger, P.C., Wolf, G.K. (2015). High-Frequency Oscillatory Ventilation in the Neonate. In: Rimensberger, P. (eds) Pediatric and Neonatal Mechanical Ventilation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01219-8_45

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-01219-8_45

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-01218-1

  • Online ISBN: 978-3-642-01219-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics