Skip to main content

NMDA Receptor Antagonists

  • Chapter
  • First Online:
Pain

Abstract

NMDA receptor antagonists have a number of indications in chronic and acute pain. While ketamine represents the most frequently utilized analgesic from this group, other agents possess similar properties. The use of ketamine has been associated with significantly improved perioperative and chronic pain relief and decreased opioid requirements.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Petrenko AB, Yamakura T, Baba H, Shimoji K. The role of N-Methyl-D-Aspartate (NMDA) receptors in pain: a review. Anesth Analg. 2003;97:1108–16.

    Article  CAS  Google Scholar 

  2. Himmelseher S, Durieux ME. Ketamine for perioperative pain management. Anesthesiolgy. 2005;102:211–20.

    Article  Google Scholar 

  3. Vadivelu N, Schermer E, Kodumudi V, Belani K, Urman R, Kaye A. Role of ketamine for analgesia in adults and children. J Anaesthesiol Clin Pharmacol. 2016;32:298–306.

    Article  CAS  Google Scholar 

  4. Subramaniam K, Subramaniam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg. 2004;99:482–95.

    Article  CAS  Google Scholar 

  5. Suzuki M. Role of N-methyl-D-aspartate receptor antagonists in postoperative pain management. Curr Opin Anaesthesiol. 2009;22:618–22.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kristopher Schroeder .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Schroeder, C., Schroeder, K. (2019). NMDA Receptor Antagonists. In: Abd-Elsayed, A. (eds) Pain. Springer, Cham. https://doi.org/10.1007/978-3-319-99124-5_62

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-99124-5_62

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-99123-8

  • Online ISBN: 978-3-319-99124-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics