Abstract
This chapter provides essential definitions and overviews important constructs and methods within the subdomain of clinical research informatics. The chapter also highlights theoretical and practical contributions from other disciplines. This chapter sets the tone and scope for the text, highlights important themes, and describes the content and organization of chapters.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Mayer D. A brief history of medicine and statistics. In:Essential evidence-based medicine. Cambridge: Cambridge University Press; 2004. p. 1–8.
Atkins HJ. The three pillars of clinical research. Br Med J. 1958;2(5112):1547–53.
Bacchieri A, Della Cioppa G. Fundamentals of clinical research: bridging medicine, statistics and operations, Statistics for biology and health. Milan: Springer; 2007.
Friedman CP. A “fundamental theorem” of biomedical informatics. J Am Med Inform Assoc. 2009;16(2):169–70.
NIH. The NIH Director’s panel on clinical research report to the advisory committee to the NIH director, December, 1997. 1997. [cited 2011 May 15]. Available from: http://www.oenb.at/de/img/executive_summary%2D%2Dnih_directors_panel_on_clinical_research_report_12_97_tcm14-48582.pdf.
Embi PJ, Payne PR. Clinical research informatics: challenges, opportunities and definition for an emerging domain. J Am Med Inform Assoc. 2009;16(3):316–27.
Sanchez-Pinto L, Mosa ASM, Fultz-Hollis K, Tachinardi U, Barnett WK, Embi PJ. The emerging role of the chief research informatics officer in academic health centers. Appl Clin Inform. 2017;8(3):845–53.
Forrest WH, Bellville JW. The use of computers in clinical trials. Br J Anaesth. 1967;39:311.
Pryor DB, et al. Features of TMR for a successful clinical and research database. In: Proceedings of the Sixth Annual Symposium on Computer Applications in Medical Care. Blum BI (ed). New York: IEEE, 1982.
Blois MS. Medical records and clinical databases: what is the difference? MD Comput. 1984;1(3):24–8.
Breitfeld PP, et al. Pilot study of a point-of-use decision support tool for cancer clinical trials eligibility. J Am Med Inform Assoc. 1999;6(6):466–77.
Carlson R, et al. Computer-based screening of patients with HIV/AIDS for clinical-trial eligibility. Online J Curr Clin Trials. 1995.
Mansour EG. Barriers to clinical trials. Part III: knowledge and attitudes of health care providers. Cancer. 1994;74(9 Suppl):2672–5.
ICH. Guideline for good clinical practice E6(R1). International Conference on Harmonisation. 1996.
Shortliffe EH, CImino JJ, Hannah KJ, editors. Biomedical informatics: computer applications in health care and biomedicine health informatics. New York: Springer Science+Business Media, LLC; 2006.
Hoyt R, Hersh WR, editors. Health informatics: practical guide. 7th ed. North Carolina: Morrisville, Lulu.com, 2018. 486 p.
Embi P. AMIA CRI years in review. 2018 [cited 2018 July 1]. Available from: http://www.embi.net/cri-years-in-review.html.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer International Publishing
About this chapter
Cite this chapter
Richesson, R.L., Andrews, J.E., Hollis, K.F. (2019). Introduction to Clinical Research Informatics. In: Richesson, R., Andrews, J. (eds) Clinical Research Informatics. Health Informatics. Springer, Cham. https://doi.org/10.1007/978-3-319-98779-8_1
Download citation
DOI: https://doi.org/10.1007/978-3-319-98779-8_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-98778-1
Online ISBN: 978-3-319-98779-8
eBook Packages: MedicineMedicine (R0)