Abstract
Inflammatory bowel disease may be treated with a variety of medications depending on the severity of disease, location of disease, and goals of treatment. Common medications include systemic and local glucocorticoids, antibiotics, 5-aminosalicylates, immunomodulatory agents, and biologic therapies. Each medication class carries distinct and important side effects.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Curtis J. Population-based assessment of adverse events associated with long-term glucocorticoid use. Arthritis Rheum. 2006;55(3):420–6.
Etminan M. Oral fluoroquinolone use and risk of peripheral neuropathy: a pharmacoepidemiologic study. Neurology. 2014;83(14):1261.
Khaliq Y. Fluoroquinolone-associated tendinopathy: a critical review of the literature. Clin Infect Dis. 2003;36(11):1404.
Kang J. Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG. Mol Pharmacol. 2001;59(1):122–6.
Carroll M. Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis. Antimicrob Agents Chemother. 2013;57(8):3903–9.
Deshpande A. Community-associated clostridium difficile infection and antibiotics: a meta-analysis. J Antimicrob Chemother. 2013;68(9):1951.
Box SA. Sulphasalazine in the treatment of rheumatoid arthritis. Br J Rheumatol. 1997;36(3):382–6.
Farr M. Side effect profile of 200 patients with inflammatory arthritides treated with sulphasalazine. Drugs. 1986;32(Suppl 1):49–53.
Schroeder K. Is mesalamine safe? Gastroenterol Hepatol (NY). 2007;3(11):878–9.
Chaparro M. Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients. Inflamm Bowel Dis. 2013;19(7):1404–10.
Beaugerie L. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet. 2009;374(9701):1617–25.
Te HS. Hepatic effects of long-term methotrexate use in treatment of inflammatory bowel disease. Am J Gastroenterol. 2000;95(11):3150.
Burdmann EA. Cyclosporine nephrotoxicity. Semin Nephrol. 2003;23(5):465–76.
Hoorn EJ. The cacineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension. Nat Med. 2011;17(10):1304–9.
Eidelman BH. Neurologic complications of FK 506. Transplant Proc. 1991;23(6):3175–8.
Randomized trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejection. European FK506 Multicentre Liver Study Group. Lancet. 1994;344(8920):423–8.
Hojo M. Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature. 1999;397(6719):530–4.
Strangfield A. Treatment benefit or survival of the fittest: what drives the time-dependent decrease in serious infection rates under TNF inhibition and what does this imply for the individual patient? Ann Rheum Dis. 2011;70(11):1914–20.
Cheifetz A. The incidence and management of infusion reactions to infliximab: a large center experience. Am J Gastroenerol. 2003;98(6):1315–24.
Hastings R. Neutropenia in patients receiving anti-tumor necrosis factor therapy. Arthritis Care Res (Hoboken). 2010;62(6):764.
Cleynen I. Characteristics of skin lesions associated with anti-tumor necrosis factor therapy in patients with inflammatory bowel disease: a cohort study. Ann Intern Med. 2016;164(1):10–22.
Gabriel SE. Tumor necrosis factor inhibition: a part of the solution or a part of the problem of heart failure in rheumatoid arthritis? Arthritis Rheum. 2008 Mar;58(3):637–40.
Dreyer L. Risk of multiple sclerosis during tumour necrosis factor inhibitor treatment for arthritis: a population-based study from DANBIO and the Danish multiple sclerosis registry. Ann Rheum Dis. 2016;75(4):785–6.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Voss, K. (2019). What Are the Complications of Home IBD Medications?. In: Graham, A., Carlberg, D.J. (eds) Gastrointestinal Emergencies. Springer, Cham. https://doi.org/10.1007/978-3-319-98343-1_90
Download citation
DOI: https://doi.org/10.1007/978-3-319-98343-1_90
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-98342-4
Online ISBN: 978-3-319-98343-1
eBook Packages: MedicineMedicine (R0)