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How to Induce Pacemaker-Mediated Tachycardia?

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Arrhythmia Induction in the EP Lab

Abstract

Pacemakers are devices that are used worldwide for bradyarrhythmias. They are robust devices that function properly from implantation to depletion of battery. Rarely malfunctions appear, one of them being pacemaker-mediated tachycardia in patients implanted with double-chamber devices when retrograde ventriculoatrial conduction is present. Retrograde ventriculoatrial conduction can be present in up to 50–70% of normal patients. In patients with a normal heart, usually it does not manifest clinically. Even in the case of an advanced AV block, retrograde VA conduction can still be present. Patients implanted with a cardiac device like pacemakers or defibrillators can exhibit ventriculoatrial conduction: 14% of patients with complete AV block and up to 80% of patients with sinus node disease. In patients with double-chamber pacemakers or double-chamber defibrillators, using an atrial sensing mode can serve as a second AV pathway and support reentry: antegrade pathway through the pacemaker and retrograde pathway through the AV node.

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References

  1. Westveer DC, Stewart JR, Goodfleish R, Gordon S, Timmis GC. Prevalence and significance of ventriculoatrial conduction. Pacing Clin Electrophysiol. 1984;7:784–9.

    Article  CAS  Google Scholar 

  2. Akhtar M, Damato AN, Batsford W, Ruskin JN. A comparative analysis of anterograde and retrograde conduction patterns in man. Circulation. 1975;52:766–78.

    Article  CAS  Google Scholar 

  3. Shenasa M, Gilbert CJ, Schmidt DH, Akhtar M. Procainamide and retrograde atrioventricular nodal conduction in man. Circulation. 1982;65:355–62.

    Article  CAS  Google Scholar 

  4. Richter S, Muessigbrodt A, Salmas J, Doering M, Wetzel M, Arya A, et al. Ventriculoatrial conduction and related pacemaker-mediated arrhythmias in patients implanted for atrioventricular block: an old problem revisited. Int J Cardiol. 2013;168:3300–8.

    Article  Google Scholar 

  5. Sadr-Ameli MA, Shenasa M, Lacombe P, Faugere G, Nadeau R. Effect of autonomic nervous system modulation on retrograde atrioventricular nodal conduction in the human heart. Cardiovasc Res. 1987;21:45–54.

    Article  CAS  Google Scholar 

  6. Hariman RJ, Pasquariello JL, Gomes JA, Holtzman R, El-Sherif N. Autonomic dependence of ventriculoatrial conduction. Am J Cardiol. 1985;56:285–91.

    Article  CAS  Google Scholar 

  7. Morady F, Nelson SD, Kou WH, Pratley R, Schmaltz S, De Buttleir M, et al. Electrophysiologic effects of epinephrine in humans. J Am Coll Cardiol. 1988;11:1235–44.

    Article  CAS  Google Scholar 

  8. Morady F, Kou WH, Kadish AH, Toivonen LK, Kushner JA, Schmaltz A. Epinephrine-induced reversal of verapamil’s electrophysiologic and therapeutic effects in patients with paroxysmal supraventricular tachycardia. Circulation. 1989;79:783–90.

    Article  CAS  Google Scholar 

  9. Cismaru G, Gusetu G, Muresan L, Rosu R, Andronache M, Matuz R, et al. Recovery of ventriculo-atrial conduction after adrenaline in patients implanted with pacemakers. Pacing Clin Electrophysiol. 2015;38:857–63.

    Article  Google Scholar 

  10. Adams CW. Retrograde atrial conduction with complete heart block following implantation of an internal ventricular pacemaker. Dis Chest. 1963;43:544–5.

    Article  CAS  Google Scholar 

  11. Castillo C, Samet P. Retrograde conduction in complete heart block. Br Heart J. 1967;29:553–8.

    Article  CAS  Google Scholar 

  12. Hayes DL, Furman S. Atrio-ventricular and ventriculo-atrial conduction times in patients undergoing pacemaker implant. Pacing Clin Electrophysiol. 1983;6:38–46.

    Article  CAS  Google Scholar 

  13. Touboul P, Huerta F, Delahaye JP. Retrograde conduction in complete atrioventricular block. Study using His bundle recordings. Br Heart J. 1976;38:706–11.

    Article  CAS  Google Scholar 

  14. Josephson ME. Clinical cardiac electrophysiology: techniques and interpretation. 4th ed. Philadelphia: Lippincott Williams and Wilkins; 2008. p. 106–7.

    Google Scholar 

  15. Akhtar M. Retrograde conduction in man. PACE. 1981;4:548–62.

    Article  CAS  Google Scholar 

  16. Kashani IA, Shakibi JG, Siassi B. Effect of verapamil on retrograde ventriculoatrial conduction in children. Jpn Heart J. 1980;21:485–90.

    Article  CAS  Google Scholar 

  17. Shanasa M, Denker S, Mahmud R, Lehmann M, Murthy VS, Akhtar M. Effect of verapamil on retrograde atrioventricular nodal conduction in the human heart. J Am Coll Cardiol. 1983;2:545–50.

    Article  Google Scholar 

  18. Reddy CP, Kuo CS. Effect of amiodarone on retrograde conduction and refractoriness of the His-Purkinje system in man. Br Heart J. 1984;51:648–53.

    Article  CAS  Google Scholar 

  19. Dougherty AH, Rinkenberger RL, Naccarelli GV. Effect of pharmacologic autonomic blockade on ventriculoatrial conduction. Am J Cardiol. 1986;57:1274–9.

    Article  CAS  Google Scholar 

  20. Den Dulk K, Lindemans FW, Bar FW, Wellens HJ. Pacemaker related tachycardias. Pacing Clin Electrophysiol. 1982;5:471–5.

    Article  Google Scholar 

  21. Bathen J, Gundersen T, Forfang K. Tachycardias related to atrial synchronous ventricular pacing. Pacing Clin Electrophysiol. 1982;5:471–5.

    Article  CAS  Google Scholar 

  22. Barold SS, Levine PA. Pacemaker repetitive nonreentrant ventriculoatrial synchronous rhythm. A review. J Interv Card Electrophysiol. 2001;5:45–58.

    Article  CAS  Google Scholar 

  23. Barold SS. Repetitive reentrant and nonreentrant ventriculoatrial synchrony in dual chamber pacing. Clin Cardiol. 1991;14:754–63.

    Article  CAS  Google Scholar 

  24. Bathen J, Gundersen T, Forfang K. Tachycardia related to atrial synchronous ventricular pacing. PACE. 1982;5:471–5.

    Article  CAS  Google Scholar 

  25. Frumin H, Furman S. Endless loop tachycardia started by an atrial premature complex in a patient with dual chamber pacemaker. J Am Coll Cardiol. 1985;5:707–10.

    Article  CAS  Google Scholar 

  26. Ausubel K, Gabry MD, Klementowicz PT, Furman S. Pacemaker-mediated endless loop tachycardia at rates below the upper rate limit. Am J Cardiol. 1988;61:465–7.

    Article  CAS  Google Scholar 

  27. Klementowicz P, Ausubel K, Furman S. The dynamic nature of ventriculoatrial conduction. PACE. 1988;11:1917–28.

    Article  Google Scholar 

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Gabriel, G. et al. (2019). How to Induce Pacemaker-Mediated Tachycardia?. In: Cismaru, G. (eds) Arrhythmia Induction in the EP Lab. Springer, Cham. https://doi.org/10.1007/978-3-319-92729-9_21

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  • DOI: https://doi.org/10.1007/978-3-319-92729-9_21

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-92728-2

  • Online ISBN: 978-3-319-92729-9

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