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Binder Jet Printing in Pharmaceutical Manufacturing

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3D Printing of Pharmaceuticals

Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series ((AAPS,volume 31))

Abstract

Binder jet printing is arguably the most successful three-dimensional printing (3DP) technology in the pharmaceutical industry to date. In 2015, the binder jet process was adapted as an alternative mass manufacturing technique to enable the production of Spritam® (the first 3D printed tablet) approved by the Food and Drug Administration (FDA). Binder jet printing is expected to continue making a widespread impact to formulation manufacture over the next decade. In particular, binder jet printing offers benefits of producing oral dosage forms with unique release characteristics ranging from fast-dissolving through to controlled-release platforms. This chapter aims to discuss the history and methodology of binder jet printing, pharmaceutical and medical applications, considerations for formulations development and advantages and disadvantages of such processes in the pharmaceutical space.

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Author information

Authors and Affiliations

  1. Department of Pharmaceutics, UCL School of Pharmacy, University College London, London, UK

    Sarah J. Trenfield, Christine M. Madla, Abdul W. Basit & Simon Gaisford

  2. FabRx Ltd., Ashford, Kent, UK

    Abdul W. Basit & Simon Gaisford

Authors
  1. Sarah J. Trenfield
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  2. Christine M. Madla
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  3. Abdul W. Basit
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  4. Simon Gaisford
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Corresponding author

Correspondence to Sarah J. Trenfield .

Editor information

Editors and Affiliations

  1. Department of Pharmaceutics, UCL School of Pharmacy, University College London, London, United Kingdom

    Abdul W. Basit

  2. Department of Pharmaceutics, UCL School of Pharmacy, University College London, London, United Kingdom

    Simon Gaisford

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© 2018 American Association of Pharmaceutical Scientists

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Trenfield, S.J., Madla, C.M., Basit, A.W., Gaisford, S. (2018). Binder Jet Printing in Pharmaceutical Manufacturing. In: Basit, A., Gaisford, S. (eds) 3D Printing of Pharmaceuticals. AAPS Advances in the Pharmaceutical Sciences Series, vol 31. Springer, Cham. https://doi.org/10.1007/978-3-319-90755-0_3

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