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Mesenchymal, Fibroosseous, and Cartilaginous Orbital Tumors

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Albert and Jakobiec's Principles and Practice of Ophthalmology

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Abstract

In this chapter, the “most common” mesenchymal tumors of the orbital soft tissues and the bones constituting the orbital perimeters will be discussed; these conditions follow the format of the World Health Organization’s (WHO) Working Group on the Classification of Tumors of the Soft Tissue and Bone from 2012. In comparison with other orbital neoplasms, and particularly with respect to orbital inflammations such as cellulitis, thyroid eye disease, and idiopathic orbital inflammation, mesenchymal tumors are rare from a clinical point of view.

The best way to triangulate on the appropriate diagnosis is to synthesize the maximal amount of information obtainable from a careful clinical history, clinical examination, and multiple diagnostic modalities, such as computed tomography, magnetic resonance imaging, ultrasonography, and Doppler ultrasonography, which reveals details of blood flow within the lesions. The age of the patient, the type of symptoms produced, and the overall configuration of the lesion on imaging studies are helpful pointers toward the likely diagnosis. Rare alternative diagnoses can, on occasion, foil the suspected preoperative diagnosis, so that only the careful analysis of histopathologic, immunohistochemistry, and cytogenetic fingerprints finally settles the issue.

Frederick A. Jakobiec is deceased.

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Author information

Authors and Affiliations

  1. Ophthalmic Consultants of Vermont, South Burlington, VT, USA

    Katherine A. Lane

  2. Oculoplastic and Orbital Surgery Service, Wills Eye Hospital, Philadelphia, PA, USA

    Jurij R. Bilyk

  3. David Glendenning Cogan Laboratory of Ophthalmic Pathology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Frederick A. Jakobiec

Authors
  1. Katherine A. Lane
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  2. Jurij R. Bilyk
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  3. Frederick A. Jakobiec
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Editor information

Editors and Affiliations

  1. Department of Ophthalmology, Oregon Health & Science University Department of Ophthalmology, Portland, OR, USA

    Daniel Albert

  2. Massachusetts Eye and Ear, Boston, MA, USA

    Joan Miller

  3. Department of Ophthalmology, University of Illinois at Chicago Department of Ophthalmology, Chicago, IL, USA

    Dimitri Azar

  4. Department of Ophthalmology, Harvard Medical School, Boston, MA, USA

    Lucy H. Young

Section Editor information

  1. No affiliation provided

    Eric Steele

  2. No affiliation provided

    John Ng

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Lane, K.A., Bilyk, J.R., Jakobiec, F.A. (2020). Mesenchymal, Fibroosseous, and Cartilaginous Orbital Tumors. In: Albert, D., Miller, J., Azar, D., Young, L.H. (eds) Albert and Jakobiec's Principles and Practice of Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-90495-5_66-1

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  • DOI: https://doi.org/10.1007/978-3-319-90495-5_66-1

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