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The German Baseline Series: Evolution and History of a National BLS

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Contact Dermatitis

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Abstract

The German Contact Dermatitis Research Group (DKG) has been developing recommendations since its foundation for patch testing with the Baseline Series and with supplementary special test series. The current test series are published on the website of the DKG (https://dkg.ivdk.org/testreihen.html). Since 1989 until December 2019, 26 updates and revisions of the German Baseline Series based on changing evidence were discussed and approved by the DKG including 51 haptens or mixes in 56 concentrations. The DKG recommends to apply this Baseline Series to all patients presenting for work-up of suspected contact sensitization.

Novel scientific evidence on the increase or decrease of sensitizations against certain contact allergens, on changes of the general or specific allergen exposure, and on appropriate test concentrations and vehicles trigger considerations for revision of this national Baseline Series. Furthermore, availability of licensed patch test allergens may influence the constitution of test preparations and their concentrations in DKG test series. Historic and recent revisions of the German Baseline series, supplementary special series, and work-related test recommendation thereof as well as differences with regard to the European Baseline series are presented.

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Author information

Authors and Affiliations

  1. Division of Allergology, Paul-Ehrlich-Institut, Langen, Germany

    V. Mahler

  2. Department of Dermatology, Universitäts-Hautklinik Mainz, Mainz, Germany

    D. Becker

Authors
  1. V. Mahler
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  2. D. Becker
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Corresponding author

Correspondence to V. Mahler .

Editor information

Editors and Affiliations

  1. Amtssygehuset Gentofte Dept. Dermatology, Hellerup, Denmark

    Jeanne Duus Johansen

  2. Federal Institute for Vaccines & Biomed, Paul Ehrlich Institut Federal Institute for Vaccines & Biomed, Langen, Bayern, Germany

    Vera Mahler

  3. Institut le Bel Labo. Dermatochimie, Strasbourg CX, France

    Jean-Pierre Lepoittevin

  4. Hautklinik, Städtische Kliniken Dortmund Klinikzentrum Mitte, Dortmund, Germany

    Peter J. Frosch

1 Electronic Supplementary Material

Table 1

Evolution of the German DKG Baseline Series (1989–2020): composition, concentrations, and vehicles of patch test substances contained in the German Standard Series regularly revised and updated by the German Contact Dermatitis Research Group (DKG). Abbreviations: pet. petrolatum, Aqu aqua, HICC hydroxyisohexyl 3-cyclohexene carboxaldehyde (DOCX 70 kb)

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Mahler, V., Becker, D. (2020). The German Baseline Series: Evolution and History of a National BLS. In: Johansen, J.D., Mahler, V., Lepoittevin, JP., Frosch, P.J. (eds) Contact Dermatitis. Springer, Cham. https://doi.org/10.1007/978-3-319-72451-5_65-1

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  • DOI: https://doi.org/10.1007/978-3-319-72451-5_65-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-72451-5

  • Online ISBN: 978-3-319-72451-5

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