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Clinical Approaches to Male Factor Infertility

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Intracytoplasmic Sperm Injection

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Abstract

Over the last several decades, male fertility has declined significantly worldwide including in the United States. Much effort has primarily focused on identifying etiologies and targeting potential areas to improve semen parameters in the management of male factor infertility. In this chapter, we systematically and comprehensively discussed the evaluation and therapeutic options of male factor infertility in this modern era of intracytoplasmic sperm injection (ICSI).

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Abbreviations

ASA:

Antisperm antibodies

AUA:

American Urological Association

CASA:

Computer-aided sperm analysis

CBAVD:

Congenital bilateral absence of the vasa deferentia

CFTR:

Cystic fibrosis transmembrane conductance regulator

CLIA:

Clinical laboratory improvement amendments

FSH:

Follicle-stimulating-hormone

HOS:

Hypoosmotic swelling

ICSI:

Intracytoplasmic sperm injection

IUI:

Intrauterine insemination

IVF:

In vitro fertilization

LH:

Luteinizing hormone

MicroTESE:

Microscopic testicular sperm extraction

RCTs:

Randomized controlled trials

ROS:

Reactive oxygen species

SA:

Semen analysis

SPA:

Sperm penetration assay

TRUS:

Transrectral Ultrasonography

WHO:

World Health Organization

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Author information

Authors and Affiliations

  1. Department of Urology, University of Washington, Seattle, WA, USA

    Omer A. Raheem

  2. Department of Urology, University of California San Diego Health, San Diego, CA, USA

    Tung-Chin Hsieh

Authors
  1. Omer A. Raheem
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  2. Tung-Chin Hsieh
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Corresponding author

Correspondence to Tung-Chin Hsieh .

Editor information

Editors and Affiliations

  1. Center for Reproductive Medicine, Weill Cornell Medical College, New York, New York, USA

    Gianpiero D. Palermo

  2. Center for Advanced Genetics, San Clemente, California, USA

    E. Scott Sills

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Raheem, O.A., Hsieh, TC. (2018). Clinical Approaches to Male Factor Infertility. In: Palermo, G., Sills, E. (eds) Intracytoplasmic Sperm Injection. Springer, Cham. https://doi.org/10.1007/978-3-319-70497-5_9

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  • DOI: https://doi.org/10.1007/978-3-319-70497-5_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-70496-8

  • Online ISBN: 978-3-319-70497-5

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