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Skin Bioengineering

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Kanerva’s Occupational Dermatology

Abstract

Noninvasive techniques provide useful and objective information on skin barrier efficiency, skin color, and skin structure in general; therefore, these techniques can be of support in investigating contact dermatitis and irritation in particular. However, their use can be sometimes cumbersome and complex especially in terms of standardization of measures and interpretation of results.

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References

  • Barel AO et al (1991) Non-invasive electrical measurements for evaluating the water content of the horny layer: comparison between capacitance and conductance measurements. In: Scott RC et al (eds) Prediction of percutaneous penetration: methods, measurements, modelling. IBC Technical Services Ltd., London, p 46

    Google Scholar 

  • Berardesca E (1997) EEMCO guidance for the assessment of stratum corneum hydration: electrical methods. Skin Res Technol 3:126–132

    Article  CAS  PubMed  Google Scholar 

  • Berardesca E, Borroni G (1995) Instrumental evaluation of cutaneous hydration. Clin Dermatol 13(4):323–327

    Article  CAS  PubMed  Google Scholar 

  • Berardesca E, Maibach HI (1988) Bioengineering and the patch test. Contact Dermatitis 18(1):3–9

    Article  CAS  PubMed  Google Scholar 

  • Berardesca E et al (1998) Differences in stratum corneum pH gradient when comparing white Caucasian and black African-American skin. Br J Dermatol 139(5):855–857

    Article  CAS  PubMed  Google Scholar 

  • Berardesca E, Leveque JL, Masson P (2002) EEMCO guidance for the measurement of skin microcirculation. Skin Pharmacol Appl Ski Physiol 15(6):442–456

    Article  Google Scholar 

  • Berardesca E, Loden M, Serup J, Masson P, Rodrigues L (2018) The revised EEMCO guidance for the in vivo measurement of water in the skin. Skin Res Technol. https://doi.org/10.1111/srt.12599 in press

    Article  PubMed  Google Scholar 

  • Berndt U, Hinnen U, Iliev D, Elsner P (1999) Is occupational irritant contact dermatitis predictable by cutaneous bioengineering methods? Results of the Swiss metalworkers’ eczema study (PROMETES). Dermatology 198(4):351–354

    Article  CAS  Google Scholar 

  • Bircher A et al (1994) Guidelines for measurement of cutaneous blood flow by laser Doppler flowmetry. A report from the standardization Group of the European Society of contact dermatitis. Contact Dermatitis 30(2):65–72

    Article  CAS  PubMed  Google Scholar 

  • Bornkessel A et al (2005) Investigation of a washing emulsion for sensitive skin-an application test. Skin Res Technol 11(1):53–60

    Article  CAS  PubMed  Google Scholar 

  • Distante F et al (2002) Intra- and inter- individual differences in sensitive skin. Cosmetic Toilet Mag 117(7):39–46

    Google Scholar 

  • EEC note for guidance: good clinical practice for trials on medicinal products in the European Community (1990) CPMP working party on efficacy of medicinal products. Pharmacol Toxicol 67(4):361–372

    Article  Google Scholar 

  • Ehlers C et al (2001) Comparison of two pH meters used for skin surface pH measurement: the pH meter “pH900” from Courage & Khazaka versus the pH meter “1140” from Mettler Toledo. Skin Res Technol 7(2):84–89

    Article  CAS  PubMed  Google Scholar 

  • Fluhr JW, Elias PM (2002) Stratum corneum pH: formation and function of the “Acid Mantle”. Exog Dermatol 1:163–175

    Article  CAS  Google Scholar 

  • Fluhr JW, Darlenski R, Angelova-Fischer I et al (2008) Skin irritation and sensitization: mechanisms and new approaches for risk assessment 1. Skin irritation. Skin Pharmacol Physiol 21:124–135

    CAS  Google Scholar 

  • Fullerton A et al (1996) Guidelines for measurement of skin colour and erythema. A report from the standardization Group of the European Society of contact dermatitis. Contact Dermatitis 35(1):1–10

    Article  CAS  PubMed  Google Scholar 

  • Issachar N et al (1997) pH measurements during lactic acid stinging test in normal and sensitive skin. Contact Dermatitis 36(3):152–155

    Article  CAS  PubMed  Google Scholar 

  • Issachar N et al (1998) Correlation between percutaneous penetration of methyl nicotinate and sensitive skin, using laser Doppler imaging. Contact Dermatitis 39(4):182–186

    Article  CAS  PubMed  Google Scholar 

  • John SM, Uter W, Schwanitz H (2000) Relevance of multiparametric skin bioengineering in a prospectively followed cohort of junior hairdressers. Contact Dermatitis 43:161–168

    Article  CAS  Google Scholar 

  • Kütting B, Uter W, Baumeister T, Schaller B, Weistenhöfer W, Drexler H (2010) Non-invasive bioengineering methods in an intervention study in 1020 male metal workers: results and implications for occupational dermatology. Contact Dermatitis 62(5):272–278

    Article  PubMed  Google Scholar 

  • Nilsson GE (1977) Measurement of water exchange through skin. Med Biol Eng Comput 15(3):209–218

    Article  CAS  PubMed  Google Scholar 

  • Parra JL, Paye M (2003) EEMCO guidance for the in vivo assessment of skin surface pH. Skin Pharmacol Appl Ski Physiol 16(3):188–202

    Article  CAS  Google Scholar 

  • Pinnagoda J et al (1989) Transepidermal water loss with and without sweat gland inactivation. Contact Dermatitis 21(1):16–22

    Article  CAS  PubMed  Google Scholar 

  • Pinnagoda J et al (1990) Guidelines for transepidermal water loss (TEWL) measurement. A report from the standardization Group of the European Society of contact dermatitis. Contact Dermatitis 22(3):164–178

    Article  CAS  PubMed  Google Scholar 

  • Robinson S, Robinsonc AH (1954) Chemical composition of sweat. Physiol Rev 34(2):202–220

    Article  CAS  PubMed  Google Scholar 

  • Rogiers V (2001) EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences. Skin Pharmacol Appl Ski Physiol 14(2):117–128

    Article  CAS  Google Scholar 

  • Villarama CD, Maibach H (2004) Sensitive skin and transepidermal water loss. In: Fluhr JW et al (eds) Bioengeneering of the skin: water and stratum corneum, 2nd edn. CRC Press, Boca Raton

    Google Scholar 

  • Wahlberg JE, Nilsson G (1984) Skin irritancy from propylene glycol. Acta Derm Venereol 64(4):286–290

    CAS  PubMed  Google Scholar 

  • Wilhelm KP, Cua A, Maibach H (1991) Skin aging. Effect on transepidermal water loss, stratum corneum hydration, skin surface pH, and casual sebum content. Arch Dermatol 127(12):1806–1809

    Article  CAS  PubMed  Google Scholar 

  • Wu Y et al (2003) Correlation between stinging, TEWL and capacitance. Skin Res Technol 9(2):90–93

    Article  PubMed  Google Scholar 

  • Yosipovitch G et al (1993) Skin surface pH in intertriginous areas in NIDDM patients. Possible correlation to candidal intertrigo. Diabetes Care 16(4):560–563

    Article  CAS  PubMed  Google Scholar 

  • Yosipovitch G et al (2004) Circadian and ultradian (12 h) variations of skin blood flow and barrier function in non-irritated and irritated skin-effect of topical corticosteroids. J Invest Dermatol 122(3):824–829

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. San Gallicano Dermatological Institute, Rome, Italy

    Enzo Berardesca & Cameli Norma

Authors
  1. Enzo Berardesca
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  2. Cameli Norma
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Corresponding author

Correspondence to Enzo Berardesca .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany

    Swen Malte John

  2. National Allergy Research Centre, Department of Dermatology and Allergy, Herlev-Gentofte University Hospital, Hellerup, Hellerup, Denmark

    Jeanne Duus Johansen

  3. Department of Dermatology and Allergology, VU University Medical Center, Amsterdam, The Netherlands

    Thomas Rustemeyer

  4. Department of Dermatology, University Hospital Jena, Jena, Germany

    Peter Elsner

  5. Department of Dermatology, University of California, San Francisco, CA, USA

    Howard I. Maibach

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Berardesca, E., Norma, C. (2020). Skin Bioengineering. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-68617-2_88

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  • DOI: https://doi.org/10.1007/978-3-319-68617-2_88

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-68615-8

  • Online ISBN: 978-3-319-68617-2

  • eBook Packages: MedicineReference Module Medicine

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