Abstract
Skin color is determined by many factors (Table 1) of which melanocyte derived epidermal melanin is the most important. The melanocyte is a dendritic cell present in the basal layer of the epidermis with no desmosomes or tonofilaments. Melanocytes arise from the neural crest as melanoblasts and migrate to the dermis, hair follicles, leptomeninges, uveal tract, and retina. By the eighth week of intrauterine life, they start to migrate from the dermis to the epidermis and this process will be completed prior to birth (Nordlund and Ortonne 2006; Nordlund et al. 2006; Nordlund 2007; Ansty 2010; Yamaguchi and Hearing 2014).
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Yazdani, M. (2020). Pigment Disorders. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-68617-2_27
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DOI: https://doi.org/10.1007/978-3-319-68617-2_27
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